| Structure and function of the polymeric mucins in airways mucus DJ Thornton, K Rousseau, MA McGuckin Annu. Rev. Physiol. 70, 459-486, 2008 | 918 | 2008 |
| Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis CK Heazlewood, MC Cook, R Eri, GR Price, SB Tauro, D Taupin, ... PLoS medicine 5 (3), e54, 2008 | 815 | 2008 |
| Muc5b is required for airway defence MG Roy, A Livraghi-Butrico, AA Fletcher, MM McElwee, SE Evans, ... Nature 505 (7483), 412-416, 2014 | 752 | 2014 |
| From mucins to mucus: toward a more coherent understanding of this essential barrier DJ Thornton, JK Sheehan Proceedings of the American Thoracic Society 1 (1), 54-61, 2004 | 471 | 2004 |
| Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B S Kirkham, JK Sheehan, D Knight, PS Richardson, DJ Thornton Biochemical Journal 361 (3), 537-546, 2002 | 429 | 2002 |
| Muc5ac: a critical component mediating the rejection of enteric nematodes SZ Hasnain, CM Evans, M Roy, AL Gallagher, KN Kindrachuk, L Barron, ... Journal of Experimental Medicine 208 (5), 893-900, 2011 | 322 | 2011 |
| Respiratory mucins: identification of core proteins and glycoforms DJ Thornton, I Carlstedt, M Howard, PL Devine, MR Price, JK Sheehan Biochemical Journal 316 (3), 967-975, 1996 | 237 | 1996 |
| Identification of two glycoforms of the MUC5B mucin in human respiratory mucus: evidence for a cysteine-rich sequence repeated within the molecule DJ Thornton, M Howard, N Khan, JK Sheehan Journal of Biological Chemistry 272 (14), 9561-9566, 1997 | 232 | 1997 |
| Mucin gene deficiency in mice impairs host resistance to an enteric parasitic infection SZ Hasnain, H Wang, JE Ghia, N Haq, Y Deng, A Velcich, RK Grencis, ... Gastroenterology 138 (5), 1763-1771. e5, 2010 | 220 | 2010 |
| Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? M Kesimer, S Kirkham, RJ Pickles, AG Henderson, NE Alexis, G DeMaria, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 296 (1 …, 2009 | 210 | 2009 |
| Mucins: the frontline defence of the lung C Ridley, DJ Thornton Biochemical Society Transactions 46 (5), 1099-1106, 2018 | 184 | 2018 |
| Calcium-dependent protein interactions in MUC5B provide reversible cross-links in salivary mucus BDE Raynal, TE Hardingham, JK Sheehan, DJ Thornton Journal of Biological Chemistry 278 (31), 28703-28710, 2003 | 184 | 2003 |
| Salivary mucin MG1 is comprised almost entirely of different glycosylated forms of the MUC5B gene product DJ Thornton, N Khan, R Mehrotra, M Howard, JK Sheehan, E Veerman, ... Glycobiology 9 (3), 293-302, 1999 | 181 | 1999 |
| The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation FR Svedberg, SL Brown, MZ Krauss, L Campbell, C Sharpe, M Clausen, ... Nature immunology 20 (5), 571-580, 2019 | 167 | 2019 |
| MUC5B is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease S Kirkham, U Kolsum, K Rousseau, D Singh, J Vestbo, DJ Thornton American journal of respiratory and critical care medicine 178 (10), 1033-1039, 2008 | 162 | 2008 |
| Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix AJ Reardon, M Le Goff, MD Briggs, D McLeod, JK Sheehan, DJ Thornton, ... Journal of biological chemistry 275 (3), 2123-2129, 2000 | 158 | 2000 |
| Analysis of respiratory mucus glycoproteins in asthma: a detailed study from a patient who died in status asthmaticus. JK Sheehan, PS Richardson, DC Fung, M Howard, DJ Thornton American journal of respiratory cell and molecular biology 13 (6), 748-756, 1995 | 155 | 1995 |
| Mucus glycoproteins from ‘normal’human tracheobronchial secretion DJ Thornton, JR Davies, M Kraayenbrink, PS Richardson, JK Sheehan, ... Biochemical journal 265 (1), 179-186, 1990 | 153 | 1990 |
| Particle tracking microrheology of purified gastrointestinal mucins P Georgiades, PDA Pudney, DJ Thornton, TA Waigh Biopolymers 101 (4), 366-377, 2014 | 148 | 2014 |
| Cystic fibrosis: an inherited disease affecting mucin-producing organs C Ehre, C Ridley, DJ Thornton The international journal of biochemistry & cell biology 52, 136-145, 2014 | 145 | 2014 |
Richard GrencisProfessor of immunology, Manchester UniversityVerified email at manchester.ac.uk
