| Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interaction with actin A Ishijima, H Kojima, T Funatsu, M Tokunaga, H Higuchi, H Tanaka, ... Cell 92 (2), 161-171, 1998 | 629 | 1998 |
| In vivo Real-time Tracking of Single Quantum Dots Conjugated with Monoclonal Anti-HER2 Antibody in Tumors of Mice H Tada, H Higuchi, TM Wanatabe, N Ohuchi Cancer research 67 (3), 1138-1144, 2007 | 481 | 2007 |
| Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein S Toba, TM Watanabe, L Yamaguchi-Okimoto, YY Toyoshima, H Higuchi Proceedings of the National Academy of Sciences 103 (15), 5741-5745, 2006 | 407 | 2006 |
| Mechanics of single kinesin molecules measured by optical trapping nanometry H Kojima, E Muto, H Higuchi, T Yanagida Biophysical journal 73 (4), 2012-2022, 1997 | 391 | 1997 |
| Chemomechanical coupling of the forward and backward steps of single kinesin molecules M Nishiyama, H Higuchi, T Yanagida Nature Cell Biology 4 (10), 790-797, 2002 | 358 | 2002 |
| Dynein arms are oscillating force generators C Shingyoji, H Higuchi, M Yoshimura, E Katayama, T Yanagida Nature 393 (6686), 711-714, 1998 | 288 | 1998 |
| Multiple-and single-molecule analysis of the actomyosin motor by nanometer-piconewton manipulation with a microneedle: unitary steps and forces A Ishijima, H Kojima, H Higuchi, Y Harada, T Funatsu, T Yanagida Biophysical journal 70 (1), 383-400, 1996 | 277 | 1996 |
| Butanedione monoxime suppresses contraction and ATPase activity of rabbit skeletal muscle H Higuchi, S Takemori The Journal of Biochemistry 105 (4), 638-643, 1989 | 261 | 1989 |
| Single-molecule analysis of the actomyosin motor using nano-manipulation A Ishijima, Y Harada, H Kojima, T Funatsu, H Higuchi, T Yanagida Biochemical and biophysical research communications 199 (2), 1057-1063, 1994 | 254 | 1994 |
| Compliance of thin filaments in skinned fibers of rabbit skeletal muscle H Higuchi, T Yanagida, YE Goldman Biophysical journal 69 (3), 1000-1010, 1995 | 251 | 1995 |
| Laser tweezers in cell biology. Introduction MP Sheetz Methods in cell biology 55, xi-xii, 1998 | 230 | 1998 |
| A mutant of the motor protein kinesin that moves in both directions on microtubules SA Endow, H Higuchi Nature 406 (6798), 913-916, 2000 | 229 | 2000 |
| Alternate fast and slow stepping of a heterodimeric kinesin molecule K Kaseda, H Higuchi, K Hirose Nature Cell Biology 5 (12), 1079-1082, 2003 | 223 | 2003 |
| Mechanochemical coupling of two substeps in a single myosin V motor S Uemura, H Higuchi, AO Olivares, EM De La Cruz, S Ishiwata Nature structural & molecular biology 11 (9), 877-883, 2004 | 213 | 2004 |
| Processivity of the single-headed kinesin KIF1A through biased binding to tubulin Y Okada, H Higuchi, N Hirokawa Nature 424 (6948), 574-577, 2003 | 202 | 2003 |
| Substeps within the 8-nm step of the ATPase cycle of single kinesin molecules M Nishiyama, E Muto, Y Inoue, T Yanagida, H Higuchi Nature cell biology 3 (4), 425-428, 2001 | 198 | 2001 |
| Nonlinear elasticity and an 8-nm working stroke of single myosin molecules in myofilaments M Kaya, H Higuchi Science 329 (5992), 686-689, 2010 | 192 | 2010 |
| Elastic filaments in skeletal muscle revealed by selective removal of thin filaments with plasma gelsolin. T Funatsu, H Higuchi, S Ishiwata The Journal of cell biology 110 (1), 53-62, 1990 | 176 | 1990 |
| Extensible and less-extensible domains of connectin filaments in stretched vertebrate skeletal muscle sarcomeres as detected by immunofluorescence and immunoelectron microscopy … Y Itoh, T Suzuki, S Kimura, K Ohashi, H Higuchi, H Sawada, T Shimizu, ... The Journal of Biochemistry 104 (4), 504-508, 1988 | 165 | 1988 |
| Connectin filaments link thick filaments and Z lines in frog skeletal muscle as revealed by immunoelectron microscopy. K Maruyama, T Yoshioka, H Higuchi, K Ohashi, S Kimura, R Natori The Journal of cell biology 101 (6), 2167-2172, 1985 | 161 | 1985 |
Takashi FunatsuProfessor, Graduate School of Pharmaceutical Sciences, The University of TokyoVerified email at mol.f.u-tokyo.ac.jp
