Keiichi Konoki
Keiichi Konoki
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Voltage-gated ion channels and gating modifier toxins
WA Catterall, S Cestèle, V Yarov-Yarovoy, HY Frank, K Konoki, T Scheuer
Toxicon 49 (2), 124-141, 2007
Sodium channel mutation leading to saxitoxin resistance in clams increases risk of PSP
VM Bricelj, L Connell, K Konoki, SP MacQuarrie, T Scheuer, WA Catterall, ...
Nature 434 (7034), 763-767, 2005
Chemical structures of amphidinols 5 and 6 isolated from marine dinoflagellate Amphidinium klebsii and their cholesterol-dependent membrane disruption
GK Paul, N Matsumori, K Konoki, M Murata, K Tachibana
Journal of Marine Biotechnology 5 (2-3), 0124-0128, 1997
Sites of proteolytic processing and noncovalent association of the distal C-terminal domain of CaV1. 1 channels in skeletal muscle
JT Hulme, K Konoki, TWC Lin, MA Gritsenko, DG Camp, DJ Bigelow, ...
Proceedings of the National Academy of Sciences 102 (14), 5274-5279, 2005
First identification of 5, 11-dideoxytetrodotoxin in marine animals, and characterization of major fragment ions of tetrodotoxin and its analogs by high resolution ESI-MS/MS
M Yotsu-Yamashita, Y Abe, Y Kudo, R Ritson-Williams, VJ Paul, K Konoki, ...
Marine drugs 11 (8), 2799-2813, 2013
Cholesterol-independent membrane disruption caused by triterpenoid saponins
M Hu, K Konoki, K Tachibana
Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 1299 (2 …, 1996
Total synthesis and biological evaluation of (+)‐neopeltolide and its analogues
H Fuwa, A Saito, S Naito, K Konoki, M Yotsu‐Yamashita, M Sasaki
Chemistry–A European Journal 15 (46), 12807-12818, 2009
Complex formation of amphotericin B in sterol-containing membranes as evidenced by surface plasmon resonance
R Mouri, K Konoki, N Matsumori, T Oishi, M Murata
Biochemistry 47 (30), 7807-7815, 2008
β-Adrenergic–regulated phosphorylation of the skeletal muscle CaV1. 1 channel in the fight-or-flight response
MA Emrick, M Sadilek, K Konoki, WA Catterall
Proceedings of the National Academy of Sciences 107 (43), 18712-18717, 2010
Isolation and structural determination of two novel phlorotannins from the brown alga Ecklonia kurome Okamura, and their radical scavenging activities
M Yotsu-Yamashita, S Kondo, S Segawa, YC Lin, H Toyohara, H Ito, ...
Marine Drugs 11 (1), 165-183, 2013
Isolation and structural determination of the first 8-epi-type tetrodotoxin analogs from the newt, Cynops ensicauda popei, and comparison of tetrodotoxin analogs profiles of …
Y Kudo, T Yasumoto, K Konoki, Y Cho, M Yotsu-Yamashita
Marine drugs 10 (3), 655-667, 2012
Synthesis and identification of proposed biosynthetic intermediates of saxitoxin in the cyanobacterium Anabaena circinalis (TA04) and the dinoflagellate Alexandrium tamarense …
S Tsuchiya, Y Cho, K Konoki, K Nagasawa, Y Oshima, ...
Organic & Biomolecular Chemistry 12 (19), 3016-3020, 2014
Concise Synthesis and Biological Assessment of (+)‐Neopeltolide and a 16‐Member Stereoisomer Library of 8, 9‐Dehydroneopeltolide: Identification of Pharmacophoric Elements
H Fuwa, M Kawakami, K Noto, T Muto, Y Suga, K Konoki, ...
Chemistry–A European Journal 19 (25), 8100-8110, 2013
Optimization of simultaneous analysis of tetrodotoxin, 4-epitetrodotoxin, 4, 9-anhydrotetrodotoxin, and 5, 6, 11-trideoxytetrodotoxin by hydrophilic interaction liquid …
M Yotsu-Yamashita, JH Jang, Y Cho, K Konoki
Forensic Toxicology 29 (1), 61-64, 2011
Inhibition of Maitotoxin‐Induced Ca2+ Influx in Rat Glioma C6 Cells by Brevetoxins and Synthetic Fragments of Maitotoxin
K Konoki, M Hashimoto, T Nonomura, M Sasaki, M Murata, K Tachibana
Journal of neurochemistry 70 (1), 409-416, 1998
Effects of lipid constituents on membrane-permeabilizing activity of amphidinols
N Morsy, T Houdai, K Konoki, N Matsumori, T Oishi, M Murata
Bioorganic & medicinal chemistry 16 (6), 3084-3090, 2008
Differential binding of tetrodotoxin and its derivatives to voltage‐sensitive sodium channel subtypes (Nav1.1 to Nav1.7)
T Tsukamoto, Y Chiba, M Wakamori, T Yamada, S Tsunogae, Y Cho, ...
British journal of pharmacology 174 (21), 3881-3892, 2017
Convergent synthesis and biological activity of the WXYZA′ B′ C′ ring system of maitotoxin
T Oishi, F Hasegawa, K Torikai, K Konoki, N Matsumori, M Murata
Organic letters 10 (16), 3599-3602, 2008
C5–C10 directly bonded tetrodotoxin analogues: possible biosynthetic precursors of tetrodotoxin from newts
Y Kudo, Y Yamashita, D Mebs, Y Cho, K Konoki, T Yasumoto, ...
Angewandte Chemie International Edition 53 (52), 14546-14549, 2014
Isolation of 6-Deoxytetrodotoxin from the Pufferfish, Takifugu pardalis, and a Comparison of the Effects of the C-6 and C-11 Hydroxy Groups of Tetrodotoxin on Its …
Y Kudo, J Finn, K Fukushima, S Sakugawa, Y Cho, K Konoki, ...
Journal of Natural Products 77 (4), 1000-1004, 2014
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