|AMPAR removal underlies Aβ-induced synaptic depression and dendritic spine loss|
H Hsieh, J Boehm, C Sato, T Iwatsubo, T Tomita, S Sisodia, R Malinow
Neuron 52 (5), 831-843, 2006
|Tau kinetics in neurons and the human central nervous system|
C Sato, NR Barthélemy, KG Mawuenyega, BW Patterson, BA Gordon, ...
Neuron 97 (6), 1284-1298. e7, 2018
|Notch signaling in the regulation of stem cell self-renewal and differentiation|
J Liu, C Sato, M Cerletti, A Wagers
Current topics in developmental biology 92, 367-409, 2010
|C-terminal fragment of presenilin is the molecular target of a dipeptidic γ-secretase-specific inhibitor DAPT (N-[N-(3, 5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl …|
Y Morohashi, T Kan, Y Tominari, H Fuwa, Y Okamura, N Watanabe, ...
Journal of Biological Chemistry 281 (21), 14670-14676, 2006
|A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease|
NR Barthélemy, Y Li, N Joseph-Mathurin, BA Gordon, J Hassenstab, ...
Nature medicine 26 (3), 398-407, 2020
|Structure of the catalytic pore of γ-secretase probed by the accessibility of substituted cysteines|
C Sato, Y Morohashi, T Tomita, T Iwatsubo
Journal of Neuroscience 26 (46), 12081-12088, 2006
|The C-terminal PAL motif and transmembrane domain 9 of presenilin 1 are involved in the formation of the catalytic pore of the γ-secretase|
C Sato, S Takagi, T Tomita, T Iwatsubo
Journal of Neuroscience 28 (24), 6264-6271, 2008
|Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease|
NR Barthélemy, K Horie, C Sato, RJ Bateman
Journal of Experimental Medicine 217 (11), 2020
|Pen-2 is incorporated into the γ-secretase complex through binding to transmembrane domain 4 of presenilin 1|
N Watanabe, T Tomita, C Sato, T Kitamura, Y Morohashi, T Iwatsubo
Journal of Biological Chemistry 280 (51), 41967-41975, 2005
|Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer’s disease and PET amyloid-positive patient identification|
NR Barthélemy, RJ Bateman, C Hirtz, P Marin, F Becher, C Sato, ...
Alzheimer's research & therapy 12 (1), 1-11, 2020
|Presenilin: RIP and beyond|
MR Hass, C Sato, R Kopan, G Zhao
Seminars in cell & developmental biology 20 (2), 201-210, 2009
|Aβ42 overproduction associated with structural changes in the catalytic pore of γ-secretase: common effects of Pen-2 N-terminal elongation and fenofibrate|
N Isoo, C Sato, H Miyashita, M Shinohara, N Takasugi, Y Morohashi, ...
Journal of Biological Chemistry 282 (17), 12388-12396, 2007
|Tau phosphorylation rates measured by mass spectrometry differ in the intracellular brain vs. extracellular cerebrospinal fluid compartments and are differentially affected by …|
NR Barthélemy, N Mallipeddi, P Moiseyev, C Sato, RJ Bateman
Frontiers in aging neuroscience 11, 121, 2019
|Participation of transmembrane domain 1 of presenilin 1 in the catalytic pore structure of the γ-secretase|
S Takagi, A Tominaga, C Sato, T Tomita, T Iwatsubo
Journal of Neuroscience 30 (47), 15943-15950, 2010
|An overview of notch signaling in adult tissue renewal and maintenance|
C Sato, G Zhao, XG Ilagan
Current Alzheimer Research 9 (2), 227-240, 2012
|SILK studies—capturing the turnover of proteins linked to neurodegenerative diseases|
RW Paterson, A Gabelle, BP Lucey, NR Barthélemy, CA Leckey, C Hirtz, ...
Nature Reviews Neurology 15 (7), 419-427, 2019
|TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading|
Y Xu, S Du, JA Marsh, K Horie, C Sato, A Ballabio, CM Karch, ...
Molecular psychiatry, 1-15, 2020
|CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer’s disease|
K Horie, NR Barthelemy, C Sato, RJ Bateman
Brain 144 (2), 515-527, 2021
|Loss of RBPj in postnatal excitatory neurons does not cause neurodegeneration or memory impairments in aged mice|
C Sato, M Turkoz, JT Dearborn, DF Wozniak, R Kopan, MR Hass
PloS one 7 (10), e48180, 2012
|Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain|
K Horie, NR Barthélemy, N Mallipeddi, Y Li, EE Franklin, RJ Perrin, ...
Acta neuropathologica communications 8 (1), 1-14, 2020