Jim Ray
Jim Ray
Washington University, Merck, Envoy Therapeutics, Takeda, MD Anderson
Email confirmado em mdanderson.org
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A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
B De Strooper, W Annaert, P Cupers, P Saftig, K Craessaerts, JS Mumm, ...
Nature 398 (6727), 518-522, 1999
24621999
A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1
JS Mumm, EH Schroeter, MT Saxena, A Griesemer, X Tian, DJ Pan, ...
Molecular cell 5 (2), 197-206, 2000
9902000
On the role of soluble ribonucleic acid in coding for amino acids
F Chapeville, F Lipmann, G Von Ehrenstein, B Weisblum, WJ Ray Jr, ...
Proceedings of the National Academy of Sciences of the United States of …, 1962
4371962
CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family
WJ Ray, G Bain, M Yao, DI Gottlieb
Journal of Biological Chemistry 272 (30), 18702-18708, 1997
3611997
Cell surface presenilin-1 participates in the γ-secretase-like proteolysis of Notch
WJ Ray, M Yao, J Mumm, EH Schroeter, P Saftig, M Wolfe, DJ Selkoe, ...
Journal of Biological Chemistry 274 (51), 36801-36807, 1999
3261999
Retinoic acid promotes neural and represses mesodermal gene expression in mouse embryonic stem cells in culture
G Bain, WJ Ray, M Yao, DI Gottlieb
Biochemical and biophysical research communications 223 (3), 691-694, 1996
3201996
From embryonal carcinoma cells to neurons: the P19 pathway
G Bain, WJ Ray, M Yao, DI Gottlieb
Bioessays 16 (5), 343-348, 1994
2921994
Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation
L Ma, MA Seager, M Wittmann, M Jacobson, D Bickel, M Burno, K Jones, ...
Proceedings of the National Academy of Sciences 106 (37), 15950-15955, 2009
2812009
Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male …
KH Clodfelter, MG Holloway, P Hodor, SH Park, WJ Ray, DJ Waxman
Molecular endocrinology 20 (6), 1333-1351, 2006
2072006
Evidence for a physical interaction between presenilin and Notch
WJ Ray, M Yao, P Nowotny, J Mumm, W Zhang, JY Wu, R Kopan, ...
Proceedings of the National Academy of Sciences 96 (6), 3263-3268, 1999
2031999
Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid β-protein generation
W Xia, WJ Ray, BL Ostaszewski, T Rahmati, WT Kimberly, MS Wolfe, ...
Proceedings of the National Academy of Sciences 97 (16), 9299-9304, 2000
1832000
Inhibition of calcineurin-mediated endocytosis and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid β oligomer-induced synaptic disruption
WQ Zhao, F Santini, R Breese, D Ross, XD Zhang, DJ Stone, M Ferrer, ...
Journal of Biological Chemistry 285 (10), 7619-7632, 2010
1732010
Identification of genetic pathways activated by the androgen receptor during the induction of proliferation in the ventral prostate gland
PV Nantermet, J Xu, Y Yu, P Hodor, D Holder, S Adamski, MA Gentile, ...
Journal of Biological Chemistry 279 (2), 1310-1322, 2004
1522004
LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease
J Majercak, WJ Ray, A Espeseth, A Simon, XP Shi, C Wolffe, K Getty, ...
Proceedings of the National Academy of Sciences 103 (47), 17967-17972, 2006
1002006
A simple procedure for removing contaminating aldehydes and peroxides from aqueous solutions of polyethylene glycols and of nonionic detergents that are based on the …
WJ Ray Jr, JM Puvathingal
Analytical biochemistry 146 (2), 307-312, 1985
911985
Androgen-mediated improvement of body composition and muscle function involves a novel early transcriptional program including IGF1, mechano growth factor, and induction of β …
MA Gentile, PV Nantermet, RL Vogel, R Phillips, D Holder, P Hodor, ...
Journal of molecular endocrinology 44 (1), 55, 2010
852010
[57] Photochemical oxidation
WJ Ray Jr
Methods in enzymology 11, 490-497, 1967
841967
Androgenic induction of growth and differentiation in the rodent uterus involves the modulation of estrogen-regulated genetic pathways
PV Nantermet, P Masarachia, MA Gentile, B Pennypacker, J Xu, D Holder, ...
Endocrinology 146 (2), 564-578, 2005
792005
Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging
AA Podtelezhnikov, KQ Tanis, M Nebozhyn, WJ Ray, DJ Stone, ...
PloS one 6 (12), e29610, 2011
762011
The muscarinic M1 receptor positive allosteric modulator PQCA improves cognitive measures in rat, cynomolgus macaque, and rhesus macaque
JM Uslaner, D Eddins, V Puri, CE Cannon, J Sutcliffe, CS Chew, ...
Psychopharmacology 225 (1), 21-30, 2013
722013
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