| A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine NC Wu, SJ Zost, AJ Thompson, D Oyen, CM Nycholat, R McBride, ... PLoS pathogens 13 (10), e1006682, 2017 | 240 | 2017 |
| A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein J Tan, BK Sack, D Oyen, I Zenklusen, L Piccoli, S Barbieri, M Foglierini, ... Nature medicine 24 (4), 401-407, 2018 | 193 | 2018 |
| Electron-microscopy-based epitope mapping defines specificities of polyclonal antibodies elicited during HIV-1 BG505 envelope trimer immunization M Bianchi, HL Turner, B Nogal, CA Cottrell, D Oyen, M Pauthner, ... Immunity 49 (2), 288-300. e8, 2018 | 173 | 2018 |
| Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein D Oyen, JL Torres, U Wille-Reece, CF Ockenhouse, D Emerling, ... Proceedings of the National Academy of Sciences 114 (48), E10438-E10445, 2017 | 130 | 2017 |
| Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts D Oyen, JL Torres, CA Cottrell, C Richter King, IA Wilson, AB Ward Science advances 4 (10), eaau8529, 2018 | 68 | 2018 |
| Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates CA Cottrell, J van Schooten, CA Bowman, M Yuan, D Oyen, M Shin, ... PLoS pathogens 16 (8), e1008753, 2020 | 59 | 2020 |
| Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway D Oyen, RB Fenwick, RL Stanfield, HJ Dyson, PE Wright Journal of the American Chemical Society 137 (29), 9459-9468, 2015 | 52 | 2015 |
| Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition D Oyen, V Srinivasan, J Steyaert, JN Barlow Journal of molecular biology 407 (1), 138-148, 2011 | 44 | 2011 |
| Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum T Pholcharee, D Oyen, Y Flores-Garcia, G Gonzalez-Paez, Z Han, ... Nature communications 12 (1), 1063, 2021 | 36 | 2021 |
| Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihydrofolate reductase of Escherichia coli D Oyen, R Wechselberger, V Srinivasan, J Steyaert, JN Barlow Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (10), 2147-2157, 2013 | 34 | 2013 |
| Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein D Oyen, JL Torres, PC Aoto, Y Flores-Garcia, Š Binter, T Pholcharee, ... PLoS pathogens 16 (3), e1008373, 2020 | 31 | 2020 |
| Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion D Oyen, RB Fenwick, PC Aoto, RL Stanfield, IA Wilson, HJ Dyson, ... Journal of the American Chemical Society 139 (32), 11233-11240, 2017 | 28 | 2017 |
| Diverse antibody responses to conserved structural motifs in Plasmodium falciparum circumsporozoite protein T Pholcharee, D Oyen, JL Torres, Y Flores-Garcia, GM Martin, ... Journal of molecular biology 432 (4), 1048-1063, 2020 | 27 | 2020 |
| Slow dynamics of tryptophan–water networks in proteins RB Fenwick, D Oyen, HJ Dyson, PE Wright Journal of the American Chemical Society 140 (2), 675-682, 2018 | 26 | 2018 |
| Functional human IgA targets a conserved site on malaria sporozoites J Tan, H Cho, T Pholcharee, LS Pereira, S Doumbo, D Doumtabe, ... Science translational medicine 13 (599), eabg2344, 2021 | 23 | 2021 |
| A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum N Beutler, T Pholcharee, D Oyen, Y Flores-Garcia, RS MacGill, E Garcia, ... PLoS pathogens 18 (3), e1010409, 2022 | 18 | 2022 |
| A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity E Thai, G Costa, A Weyrich, R Murugan, D Oyen, Y Flores-Garcia, K Prieto, ... Journal of Experimental Medicine 217 (11), e20200061, 2020 | 18 | 2020 |
| Structural delineation and phase-dependent activation of the costimulatory CD27: CD70 complex W Liu, Z Maben, C Wang, KC Lindquist, M Li, V Rayannavar, IL Armenta, ... Journal of Biological Chemistry 297 (4), 2021 | 13 | 2021 |
| Multi-probe relaxation dispersion measurements increase sensitivity to protein dynamics RB Fenwick, D Oyen, PE Wright Physical Chemistry Chemical Physics 18 (8), 5789-5798, 2016 | 13 | 2016 |
| Modeling of Hidden Structures Using Sparse Chemical Shift Data from NMR Relaxation Dispersion RB Fenwick, D Oyen, H van den Bedem, HJ Dyson, PE Wright Biophysical Journal 120 (2), 296-305, 2021 | 5 | 2021 |
Nicholas C. WuUniversity of Illinois at Urbana-ChampaignVerified email at illinois.edu
