|CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis|
BZ Qian, J Li, H Zhang, T Kitamura, J Zhang, LR Campion, EA Kaiser, ...
Nature 475 (7355), 222-225, 2011
|Immune cell promotion of metastasis|
T Kitamura, BZ Qian, JW Pollard
Nature Reviews Immunology 15 (2), 73-86, 2015
|CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages|
T Kitamura, BZ Qian, D Soong, L Cassetta, R Noy, G Sugano, Y Kato, J Li, ...
Journal of Experimental Medicine 212 (7), 1043-1059, 2015
|SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion|
T Kitamura, K Kometani, H Hashida, A Matsunaga, H Miyoshi, H Hosogi, ...
Nature genetics 39 (4), 467-475, 2007
|Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling|
M Sonoshita, M Aoki, H Fuwa, K Aoki, H Hosogi, Y Sakai, H Hashida, ...
Cancer cell 19 (1), 125-137, 2011
|Stromal fibroblasts activated by tumor cells promote angiogenesis in mouse gastric cancer|
X Guo, H Oshima, T Kitmura, MM Taketo, M Oshima
Journal of Biological Chemistry 283 (28), 19864-19871, 2008
|Inactivation of chemokine (CC motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model|
T Kitamura, T Fujishita, P Loetscher, L Revesz, H Hashida, ...
Proceedings of the National Academy of Sciences 107 (29), 13063-13068, 2010
|Proinsulin C-peptide rapidly stimulates mitogen-activated protein kinases in Swiss 3T3 fibroblasts: requirement of protein kinase C, phosphoinositide 3-kinase and pertussis …|
T KITAMURA, K KIMURA, BD JUNG, K MAKONDO, S OKAMOTO, ...
Biochemical Journal 355 (1), 123-129, 2001
|Proinsulin C-peptide increases nitric oxide production by enhancing mitogen-activated protein-kinase-dependent transcription of endothelial nitric oxide synthase in aortic …|
T Kitamura, K Kimura, K Makondo, DT Furuya, M Suzuki, T Yoshida, ...
Diabetologia 46 (12), 1698-1705, 2003
|Targeting tumor-associated macrophages as a potential strategy to enhance the response to immune checkpoint inhibitors|
L Cassetta, T Kitamura
Frontiers in cell and developmental biology 6, 38, 2018
|Proinsulin C-peptide activates cAMP response element-binding proteins through the p38 mitogen-activated protein kinase pathway in mouse lung capillary endothelial cells|
T Kitamura, K Kimura, BD Jung, K Makondo, N Sakane, T Yoshida, ...
Biochemical Journal 366 (3), 737-744, 2002
|Induction and down-regulation of Sox17 and its possible roles during the course of gastrointestinal tumorigenesis|
YC Du, H Oshima, K Oguma, T Kitamura, H Itadani, T Fujimura, YS Piao, ...
Gastroenterology 137 (4), 1346-1357, 2009
|Monocytes differentiate to immune suppressive precursors of metastasis-associated macrophages in mouse models of metastatic breast cancer|
T Kitamura, D Doughty-Shenton, L Cassetta, S Fragkogianni, D Brownlie, ...
Frontiers in immunology 8, 2004, 2018
|Macrophage targeting: opening new possibilities for cancer immunotherapy|
L Cassetta, T Kitamura
Immunology 155 (3), 285-293, 2018
|Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling|
S Arimura, A Matsunaga, T Kitamura, K Aoki, M Aoki, MM Taketo
Gastroenterology 137 (2), 629-638, 2009
|Targeting macrophage-recruiting chemokines as a novel therapeutic strategy to prevent the progression of solid tumors|
D Argyle, T Kitamura
Frontiers in immunology 9, 2629, 2018
|Therapeutic potential of chemokine signal inhibition for metastatic breast cancer|
T Kitamura, JW Pollard
Pharmacological research 100, 266-270, 2015
|In vivo subcellular resolution optical imaging in the lung reveals early metastatic proliferation and motility|
D Entenberg, C Rodriguez-Tirado, Y Kato, T Kitamura, JW Pollard, ...
Intravital 4 (3), 1-11, 2015
|Keeping out the bad guys: gateway to cellular target therapy|
T Kitamura, MM Taketo
Cancer research 67 (21), 10099-10102, 2007
|Hepatocyte growth factor activates endothelial nitric oxide synthase by Ca2+-and phosphoinositide 3-kinase/Akt-dependent phosphorylation in aortic endothelial cells|
K Makondo, K Kimura, N Kitamura, T Kitamura, D Yamaji, BD Jung, ...
Biochemical Journal 374 (1), 63-69, 2003