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George Koob
George Koob
Director, National Institute on Alcohol Abuse and Alcoholism
Email confirmado em nih.gov
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Neurocircuitry of addiction
GF Koob, ND Volkow
Neuropsychopharmacology 35 (1), 217-238, 2010
61162010
Drug addiction, dysregulation of reward, and allostasis
GF Koob, M Le Moal
Neuropsychopharmacology 24 (2), 97-129, 2001
37132001
Drug abuse: hedonic homeostatic dysregulation
GF Koob, ML Moal
Science 278 (5335), 52-58, 1997
35111997
Neurobiology of addiction: a neurocircuitry analysis
GF Koob, ND Volkow
The Lancet Psychiatry 3 (8), 760-773, 2016
30462016
Drugs of abuse: anatomy, pharmacology and function of reward pathways
GF Koob
Trends in pharmacological sciences 13, 177-184, 1992
29141992
Cellular and molecular mechanisms of drug dependence
GF Koob, FE Bloom
Science 242 (4879), 715-723, 1988
27801988
Neurobiologic advances from the brain disease model of addiction
ND Volkow, GF Koob, AT McLellan
New England Journal of Medicine 374 (4), 363-371, 2016
20122016
Addiction and the brain antireward system
GF Koob, M Le Moal
Annu. Rev. Psychol. 59, 29-53, 2008
16982008
Neuroscience of addiction
GF Koob, PP Sanna, FE Bloom
Neuron 21 (3), 467-476, 1998
13421998
Transition from moderate to excessive drug intake: change in hedonic set point
SH Ahmed, GF Koob
Science 282 (5387), 298-300, 1998
12771998
A role for brain stress systems in addiction
GF Koob
Neuron 59 (1), 11-34, 2008
12192008
Plasticity of reward neurocircuitry and the'dark side'of drug addiction
GF Koob, M Le Moal
Nature neuroscience 8 (11), 1442-1444, 2005
11542005
Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress
TL Bale, A Contarino, GW Smith, R Chan, LH Gold, PE Sawchenko, ...
Nature genetics 24 (4), 410-414, 2000
10372000
Stress, dysregulation of drug reward pathways, and the transition to drug dependence
G Koob, MJ Kreek
American journal of psychiatry 164 (8), 1149-1159, 2007
10362007
Neurobiological similarities in depression and drug dependence: a self-medication hypothesis
A Markou, TR Kosten, GF Koob
Neuropsychopharmacology 18 (3), 135-174, 1998
10331998
Corticotropin releasing factor receptor 1–deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development
GW Smith, JM Aubry, F Dellu, A Contarino, LM Bilezikjian, LH Gold, ...
Neuron 20 (6), 1093-1102, 1998
10121998
Neurobiology of addiction
GF Koob
Focus 9 (1), 55-65, 2011
9642011
Corticotropin releasing factor produces behavioural activation in rats
RE Sutton, GF Koob, M Le Moal, J Rivier, W Vale
Nature 297 (5864), 331-333, 1982
9611982
Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens
DCS Roberts, GF Koob, P Klonoff, HC Fibiger
Pharmacology Biochemistry and Behavior 12 (5), 781-787, 1980
9591980
Dopamine, schizophrenia, mania, and depression: toward a unified hypothesis of cortico-striatopallido-thalamic function
NR Swerdlow, GF Koob
Behavioral and brain sciences 10 (2), 197-208, 1987
9221987
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