Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor binding JM Seckler, MD Barkley, PL Wintrode Biophysical journal 100 (1), 144-153, 2011 | 49 | 2011 |
Advances in D-amino acids in neurological research JM Seckler, SJ Lewis International journal of molecular sciences 21 (19), 7325, 2020 | 38 | 2020 |
Solution structural dynamics of HIV-1 reverse transcriptase heterodimer JM Seckler, KJ Howard, MD Barkley, PL Wintrode Biochemistry 48 (32), 7646-7655, 2009 | 37 | 2009 |
Voltage-gated potassium channel proteins and stereoselective S-nitroso-l-cysteine signaling B Gaston, L Smith, J Bosch, J Seckler, D Kunze, J Kiselar, N Marozkina, ... JCI insight 5 (18), 2020 | 25 | 2020 |
Glutathione ethyl ester reverses the deleterious effects of fentanyl on ventilation and arterial blood-gas chemistry while prolonging fentanyl-induced analgesia MW Jenkins, F Khalid, SM Baby, WJ May, AP Young, JN Bates, F Cheng, ... Scientific reports 11 (1), 6985, 2021 | 23 | 2021 |
d-Cystine di(m)ethyl ester reverses the deleterious effects of morphine on ventilation and arterial blood gas chemistry while promoting antinociception B Gaston, SM Baby, WJ May, AP Young, A Grossfield, JN Bates, ... Scientific reports 11 (1), 10038, 2021 | 22 | 2021 |
The interplay of structure and dynamics: Insights from a survey of HIV‐1 reverse transcriptase crystal structures JM Seckler, N Leioatts, H Miao, A Grossfield Proteins: Structure, Function, and Bioinformatics 81 (10), 1792-1801, 2013 | 22 | 2013 |
Detection of trace concentrations of S-nitrosothiols by means of a capacitive sensor JM Seckler, NM Meyer, ST Burton, JN Bates, B Gaston, SJ Lewis PLoS One 12 (10), e0187149, 2017 | 20 | 2017 |
Systemic administration of tempol attenuates the cardiorespiratory depressant effects of fentanyl S Baby, R Gruber, J Discala, V Puskovic, N Jose, F Cheng, M Jenkins, ... Frontiers in Pharmacology 12, 690407, 2021 | 18 | 2021 |
Possible roles of permafrost melting, atmospheric transport, and solar irradiance in the development of major coronavirus and influenza pandemics AM Hofmeister, JM Seckler, GM Criss International Journal of Environmental Research and Public Health 18 (6), 3055, 2021 | 18 | 2021 |
Nitrosyl factors play a vital role in the ventilatory depressant effects of fentanyl in unanesthetized rats JM Seckler, A Grossfield, WJ May, PM Getsy, SJ Lewis Biomedicine & Pharmacotherapy 146, 112571, 2022 | 17 | 2022 |
NADPH diaphorase detects S-nitrosylated proteins in aldehyde-treated biological tissues JM Seckler, J Shen, THJ Lewis, MA Abdulameer, K Zaman, LA Palmer, ... Scientific reports 10 (1), 21088, 2020 | 17 | 2020 |
S-nitroso-L-cysteine stereoselectively blunts the adverse effects of morphine on breathing and arterial blood gas chemistry while promoting analgesia PM Getsy, AP Young, JN Bates, SM Baby, JM Seckler, A Grossfield, ... Biomedicine & Pharmacotherapy 153, 113436, 2022 | 11 | 2022 |
D-cysteine ethyl ester and D-cystine dimethyl ester reverse the deleterious effects of morphine on arterial blood-gas chemistry and Alveolar-arterial gradient in anesthetized rats PM Getsy, AP Young, A Grossfield, JM Seckler, CG Wilson, B Gaston, ... Respiratory physiology & neurobiology 302, 103912, 2022 | 11 | 2022 |
S-Nitroso-L-Cysteine stereoselectively blunts the deleterious effects of fentanyl on breathing while augmenting antinociception in freely-moving rats PM Getsy, SM Baby, RB Gruber, B Gaston, THJ Lewis, A Grossfield, ... Frontiers in Pharmacology 13, 892307, 2022 | 9 | 2022 |
Cyclic compression increases F508 Del CFTR expression in ciliated human airway epithelium N Marozkina, J Bosch, C Cotton, L Smith, J Seckler, K Zaman, S Rehman, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 317 (2 …, 2019 | 7 | 2019 |
The ventilatory depressant actions but not the antinociceptive effects of morphine are blunted in rats receiving intravenous infusion of L-cysteine ethyl ester THJ Lewis, WJ May, AP Young, JN Bates, SM Baby, PM Getsy, RM Ryan, ... Biomedicine & Pharmacotherapy 156, 113939, 2022 | 6 | 2022 |
Compositions and methods for stimulating ventilatory and/or respiratory drive SJ Lewis, MW Jenkins, JM Seckler US Patent App. 17/696,204, 2023 | 1 | 2023 |
Hypoxia releases S-nitrosocysteine from carotid body glomus cells—relevance to expression of the hypoxic ventilatory response JM Seckler, PM Getsy, WJ May, B Gaston, SM Baby, THJ Lewis, JN Bates, ... Frontiers in Pharmacology 14, 1250154, 2023 | 1 | 2023 |
A Novel Capacitive Biosensor for the Detection of Small Molecule S-Nitrosothiols NM Meyer, S Burton, JN Bates, B Gaston, SJ Lewis, JM Seckler Biophysical Journal 112 (3), 457a, 2017 | 1 | 2017 |