Transcriptional pause release is a rate-limiting step for somatic cell reprogramming L Liu, Y Xu, M He, M Zhang, F Cui, L Lu, M Yao, W Tian, C Benda, ... Cell Stem Cell 15 (5), 574-588, 2014 | 82 | 2014 |
Direct quality control of glycoengineered erythropoietin variants T Čaval, W Tian, Z Yang, H Clausen, AJR Heck Nature Communications 9 (1), 3342, 2018 | 74 | 2018 |
Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions S Wang, Y Mao, Y Narimatsu, Z Ye, W Tian, CK Goth, E Lira-Navarrete, ... Journal of Biological Chemistry 293 (19), 7408-7422, 2018 | 71 | 2018 |
The hypoxia-inducible factor renders cancer cells more sensitive to vitamin C-induced toxicity W Tian, Y Wang, Y Xu, X Guo, B Wang, L Sun, L Liu, F Cui, Q Zhuang, ... Journal of Biological Chemistry 289 (6), 3339-3351, 2014 | 64 | 2014 |
The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells W Tian, Z Ye, S Wang, MA Schulz, J Van Coillie, L Sun, YH Chen, ... Nature communications 10 (1), 1785, 2019 | 59 | 2019 |
Targeted Analysis of Lysosomal Directed Proteins and Their Sites of Mannose-6-phosphate Modification*[S] T Čaval, J Zhu, W Tian, S Remmelzwaal, Z Yang, H Clausen, AJR Heck Molecular & Cellular Proteomics 18 (1), 16-27, 2019 | 41 | 2019 |
Generation of knockout rabbits using transcription activator-like effector nucleases Y Wang, N Fan, J Song, J Zhong, X Guo, W Tian, Q Zhang, F Cui, L Li, ... Cell regeneration 3, 1-9, 2014 | 41 | 2014 |
Glycoengineering design options for IgG1 in CHO cells using precise gene editing MA Schulz, W Tian, Y Mao, J Van Coillie, L Sun, JS Larsen, YH Chen, ... Glycobiology 28 (7), 542-549, 2018 | 38 | 2018 |
Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element J Xu, B Wang, Y Xu, L Sun, W Tian, D Shukla, R Barod, J Grillari, ... Oncogene 31 (8), 1065-1072, 2012 | 38 | 2012 |
EDEM1's mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity L Lamriben, ME Oster, T Tamura, W Tian, Z Yang, H Clausen, DN Hebert Journal of Biological Chemistry 293 (36), 13932-13945, 2018 | 35 | 2018 |
Induced pluripotent stem cells with NOTCH1 gene mutation show impaired differentiation into smooth muscle and endothelial cells: Implications for bicuspid aortic valve-related … J Jiao, W Tian, P Qiu, EL Norton, MM Wang, YE Chen, B Yang The Journal of thoracic and cardiovascular surgery 156 (2), 515-522. e1, 2018 | 34 | 2018 |
Mechanism and site of action of big dynorphin on ASIC1a CB Borg, N Braun, SA Heusser, Y Bay, D Weis, I Galleano, C Lund, ... Proceedings of the National Academy of Sciences 117 (13), 7447-7454, 2020 | 32 | 2020 |
Urine as a source of stem cells C Benda, T Zhou, X Wang, W Tian, J Grillari, HF Tse, R Grillari-Voglauer, ... Mesenchymal Stem Cells-Basics and Clinical Application I, 19-32, 2013 | 26 | 2013 |
Activity of N-acylneuraminate-9-phosphatase (NANP) is not essential for de novo sialic acid biosynthesis AP Willems, L Sun, MA Schulz, W Tian, A Ashikov, M van Scherpenzeel, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (10), 1471-1479, 2019 | 25 | 2019 |
Solving the puzzle of Parkinson’s disease using induced pluripotent stem cells P Zhao, Z Luo, W Tian, J Yang, DP Ibanez, Z Huang, MD Tortorella, ... Experimental Biology and Medicine 239 (11), 1421-1432, 2014 | 24 | 2014 |
E2F1 in renal cancer: Mr Hyde disguised as Dr Jekyll? W Tian, F Cui, MA Esteban The Journal of pathology 231 (2), 143-146, 2013 | 11 | 2013 |
The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase ISB Larsen, L Povolo, L Zhou, W Tian, KJ Mygind, J Hintze, C Jiang, ... Proceedings of the National Academy of Sciences 120 (21), e2302584120, 2023 | 8 | 2023 |
Engineering mammalian cells to produce plant-specific N-glycosylation on proteins JS Larsen, RTG Karlsson, W Tian, MA Schulz, A Matthes, H Clausen, ... Glycobiology 30 (8), 528-538, 2020 | 7 | 2020 |
Development of a bispecific immune engager using a recombinant malaria protein MA Nordmaj, ME Roberts, ES Sachse, R Dagil, AP Andersen, N Skeltved, ... Cell death & disease 12 (4), 353, 2021 | 6 | 2021 |
A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution YH Chen, W Tian, M Yasuda, Z Ye, M Song, U Mandel, C Kristensen, ... Frontiers in Bioengineering and Biotechnology 11, 1128371, 2023 | 2 | 2023 |