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Yan Jouroukhin
Yan Jouroukhin
Email confirmado em jhmi.edu
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A neuronal microtubule-interacting agent, NAPVSIPQ, reduces tau pathology and enhances cognitive function in a mouse model of Alzheimer's disease
Y Matsuoka, Y Jouroukhin, AJ Gray, L Ma, C Hirata-Fukae, HF Li, L Feng, ...
Journal of Pharmacology and Experimental Therapeutics 325 (1), 146-153, 2008
2632008
NAP protects memory, increases soluble tau and reduces tau hyperphosphorylation in a tauopathy model
N Shiryaev, Y Jouroukhin, E Giladi, E Polyzoidou, NC Grigoriadis, ...
Neurobiology of disease 34 (2), 381-388, 2009
1422009
NAP (davunetide) modifies disease progression in a mouse model of severe neurodegeneration: protection against impairments in axonal transport
Y Jouroukhin, R Ostritsky, Y Assaf, G Pelled, E Giladi, I Gozes
Neurobiology of disease 56, 79-94, 2013
1002013
Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory
N Amram, G Hacohen-Kleiman, S Sragovich, A Malishkevich, J Katz, ...
Molecular psychiatry 21 (10), 1467-1476, 2016
802016
MCT1 deletion in oligodendrocyte lineage cells causes late-onset hypomyelination and axonal degeneration
T Philips, YA Mironova, Y Jouroukhin, J Chew, S Vidensky, MH Farah, ...
Cell reports 34 (2), 2021
702021
DISC1 in astrocytes influences adult neurogenesis and hippocampus-dependent behaviors in mice
CE Terrillion, B Abazyan, Z Yang, J Crawford, AV Shevelkin, Y Jouroukhin, ...
Neuropsychopharmacology 42 (11), 2242-2251, 2017
562017
Behavioral sequelae of astrocyte dysfunction: focus on animal models of schizophrenia
M Xia, S Abazyan, Y Jouroukhin, M Pletnikov
Schizophrenia research 176 (1), 72-82, 2016
562016
Adolescent Δ9-tetrahydrocannabinol exposure and astrocyte-specific genetic vulnerability converge on nuclear factor-κB–cyclooxygenase-2 signaling to impair memory in adulthood
Y Jouroukhin, X Zhu, AV Shevelkin, Y Hasegawa, B Abazyan, A Saito, ...
Biological psychiatry 85 (11), 891-903, 2019
452019
DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders
Y Jouroukhin, Y Kageyama, V Misheneva, A Shevelkin, S Andrabi, ...
Translational psychiatry 8 (1), 76, 2018
372018
AAH2 gene is not required for dopamine-dependent neurochemical and behavioral abnormalities produced by Toxoplasma infection in mouse
R McFarland, ZT Wang, Y Jouroukhin, Y Li, O Mychko, I Coppens, J Xiao, ...
Behavioural brain research 347, 193-200, 2018
292018
D-NAP prophylactic treatment in the SOD mutant mouse model of amyotrophic lateral sclerosis: review of discovery and treatment of tauopathy
Y Jouroukhin, R Ostritsky, I Gozes
Journal of Molecular Neuroscience 48, 597-602, 2012
222012
Expression of mutant DISC1 in Purkinje cells increases their spontaneous activity and impairs cognitive and social behaviors in mice
AV Shevelkin, CE Terrillion, BN Abazyan, TJ Kajstura, YA Jouroukhin, ...
Neurobiology of disease 103, 144-153, 2017
192017
3R tau expression modifies behavior in transgenic mice
N Shiryaev, Y Jouroukhin, I Gozes
Journal of neuroscience research 88 (12), 2727-2735, 2010
162010
Astrocyte DISC1 contributes to cognitive function in a brain region-dependent manner
AV Shevelkin, CE Terrillion, Y Hasegawa, OA Mychko, Y Jouroukhin, ...
Human molecular genetics 29 (17), 2936-2950, 2020
152020
Molecular neuroimaging of post-injury plasticity
Y Jouroukhin, BAS Nonyane, AA Gilad, G Pelled
Journal of Molecular Neuroscience 54, 630-638, 2014
122014
Cell type-specific effects of mutant DISC1: a proteomics study
M Xia, JAC Broek, Y Jouroukhin, J Schoenfelder, S Abazyan, ...
Complex Psychiatry 2 (1), 28-36, 2016
82016
DISC1 signaling in cocaine addiction: Towards molecular mechanisms of co-morbidity
A Gancarz, Y Jouroukhin, A Saito, A Shevelkin, LE Mueller, A Kamiya, ...
Neuroscience research 105, 70-74, 2016
72016
Deficient mitochondrial respiration in astrocytes impairs trace fear conditioning and increases naloxone‐precipitated aversion in morphine‐dependent mice
K Murlanova, Y Jouroukhin, S Huseynov, O Pletnikova, MJ Morales, ...
Glia 70 (7), 1289-1300, 2022
42022
Overexpression of truncated human DISC1 induces appearance of hindbrain oligodendroglia in the forebrain during development
P Katsel, P Fam, W Tan, S Khan, C Yang, Y Jouroukhin, S Rudchenko, ...
Schizophrenia bulletin 44 (3), 515-524, 2018
42018
Modeling gene–environment interaction in schizophrenia
Y Jouroukhin, R McFarland, Y Ayhan, MV Pletnikov
Handbook of Behavioral Neuroscience 23, 345-360, 2016
32016
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Artigos 1–20