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Alexandra O. Silva
Alexandra O. Silva
Biomolecular Structure and Function, IBMC/i3S
Email confirmado em ibmc.up.pt
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Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity
A Mesquita, M Weinberger, A Silva, B Sampaio-Marques, B Almeida, ...
Proceedings of the National Academy of Sciences 107 (34), 15123-15128, 2010
3382010
SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy
B Sampaio-Marques, C Felgueiras, A Silva, M Rodrigues, S Tenreiro, ...
Autophagy 8 (10), 14-13, 2012
154*2012
NO-mediated apoptosis in yeast
B Almeida, S Buttner, S Ohlmeier, A Silva, A Mesquita, ...
Journal of cell science 120 (18), 3279-3288, 2007
1462007
Drug-induced apoptosis in yeast
B Almeida, A Silva, A Mesquita, B Sampaio-Marques, F Rodrigues, ...
BBA Mol Cell Res 1783 (7), 1436-1448, 2008
822008
Systemic macrophage and neutrophil destruction by secondary necrosis induced by a bacterial exotoxin in a Gram‐negative septicaemia
A Do Vale, C Costa‐Ramos, A Silva, DSP Silva, F Gärtner, ...
Cellular microbiology 9 (4), 988-1003, 2007
692007
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a specific substrate of yeast metacaspase
A Silva, B Almeida, B Sampaio-Marques, MIR Reis, S Ohlmeier, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (12), 2044-2049, 2011
572011
Yeast chronological lifespan and proteotoxic stress: is autophagy good or bad?
B Sampaio-Marques, C Felgueiras, A Silva, F Rodrigues, P Ludovico
Biochemical Society Transactions 39 (5), 1466-1470, 2011
382011
Polyglutamine expansion diseases: More than simple repeats
A Silva, AV de Almeida, S Macedo-Ribeiro
Journal of Structural Biology 201 (2), 139-154, 2018
352018
CLASP2 binding to curved microtubule tips promotes flux and stabilizes kinetochore attachments
H Girão, N Okada, TA Rodrigues, AO Silva, AC Figueiredo, Z Garcia, ...
Journal of Cell Biology 219 (2), e201905080, 2019
322019
Involvement of yeast HSP90 isoforms in response to stress and cell death induced by acetic acid
A Silva, B Sampaio-Marques, A Fernandes, L Carreto, F Rodrigues, ...
PLoS One 8 (8), e71294, 2013
322013
MIRRAGGE–minimum information required for reproducible AGGregation experiments
PM Martins, S Navarro, A Silva, MF Pinto, Z Sárkány, F Figueiredo, ...
Frontiers in molecular neuroscience 13, 582488, 2020
192020
Accurate prediction of protein beta-aggregation with generalized statistical potentials
G Orlando, A Silva, S Macedo-Ribeiro, D Raimondi, W Vranken
Bioinformatics 36 (7), 2076-2081, 2020
192020
Polyglutamine-independent features in ataxin-3 aggregation and pathogenesis of Machado-Joseph disease
AL Carvalho, A Silva, S Macedo-Ribeiro
Polyglutamine Disorders, 275-288, 2018
182018
Ser or Leu: structural snapshots of mistranslation in Candida albicans
A Silva, Z Sárkány, PJB Pereira, S Macedo-Ribeiro
Frontiers in Molecular Biosciences 1, 27, 2014
152014
Distribution of Amyloid‐Like and Oligomeric Species from Protein Aggregation Kinetics
A Silva, B Almeida, JS Fraga, P Taboada, PM Martins, S Macedo‐Ribeiro
Angewandte Chemie International Edition 56 (45), 14042-14045, 2017
142017
Molecular basis of pyruvate kinase deficiency among Tunisians: description of new mutations affecting coding and noncoding regions in the PKLR gene
M Jaouani, L Manco, M Kalai, L Chaouch, K Douzi, A Silva, S Macedo, ...
International journal of laboratory hematology 39 (2), 223-231, 2017
112017
A genuine mycobacterial thermophile: Mycobacterium hassiacum growth, survival and GpgS stability at near-pasteurization temperatures
S Alarico, D Nunes-Costa, A Silva, M Costa, S Macedo-Ribeiro, ...
Microbiology 166 (5), 474-483, 2020
72020
Probing the occurrence of soluble oligomers through amyloid aggregation scaling laws
A Silva, Z Sárkány, JS Fraga, P Taboada, S Macedo-Ribeiro, PM Martins
Biomolecules 8 (4), 108, 2018
72018
Genetic code ambiguity modulates the activity of a C. albicans MAP kinase linked to cell wall remodeling
JS Fraga, Z Sárkány, A Silva, I Correia, PJB Pereira, S Macedo-Ribeiro
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (6), 654-661, 2019
62019
Drug repurposing of dopaminergic drugs to inhibit Ataxin-3 aggregation
F Figueiredo, Z Sárkány, A Silva, D Vilasboas-Campos, P Maciel, ...
Biomedicine & Pharmacotherapy 165, 115258, 2023
22023
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Artigos 1–20