| De novo design of bioactive protein switches RA Langan, SE Boyken, AH Ng, JA Samson, G Dods, AM Westbrook, ... Nature 572 (7768), 205-210, 2019 | 249 | 2019 |
| Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs K Kundert, JE Lucas, KE Watters, C Fellmann, AH Ng, BM Heineike, ... Nature communications 10 (1), 2127, 2019 | 166 | 2019 |
| Biophysical constraints arising from compositional context in synthetic gene networks E Yeung, AJ Dy, KB Martin, AH Ng, D Del Vecchio, JL Beck, JJ Collins, ... Cell systems 5 (1), 11-24. e12, 2017 | 122 | 2017 |
| Modular and tunable biological feedback control using a de novo protein switch AH Ng, TH Nguyen, M Gómez-Schiavon, G Dods, RA Langan, SE Boyken, ... Nature 572 (7768), 265-269, 2019 | 114 | 2019 |
| Design and analysis of a proportional-integral-derivative controller with biological molecules M Chevalier, M Gómez-Schiavon, AH Ng, H El-Samad Cell systems 9 (4), 338-353. e10, 2019 | 88 | 2019 |
| Fine-tuning of photoautotrophic protein production by combining promoters and neutral sites in the cyanobacterium Synechocystis sp. strain PCC 6803 AH Ng, BM Berla, HB Pakrasi Applied and environmental microbiology 81 (19), 6857-6863, 2015 | 78 | 2015 |
| A toolkit for rapid modular construction of biological circuits in mammalian cells JP Fonseca, AR Bonny, GR Kumar, AH Ng, J Town, QC Wu, E Aslankoohi, ... ACS synthetic biology 8 (11), 2593-2606, 2019 | 53 | 2019 |
| Optogenetic control reveals differential promoter interpretation of transcription factor nuclear translocation dynamics SY Chen, LC Osimiri, M Chevalier, LJ Bugaj, TH Nguyen, RA Greenstein, ... Cell systems 11 (4), 336-353. e24, 2020 | 48 | 2020 |
| Robust, tunable genetic memory from protein sequestration combined with positive feedback T Shopera, WR Henson, A Ng, YJ Lee, K Ng, TS Moon Nucleic acids research 43 (18), 9086-9094, 2015 | 47 | 2015 |
| Multidimensional characterization of parts enhances modeling accuracy in genetic circuits M Gómez-Schiavon, G Dods, H El-Samad, AH Ng ACS Synthetic Biology 9 (11), 2917-2926, 2020 | 15 | 2020 |
| Modeling the effects of compositional context on promoter activity in an E. coli extract based transcription-translation system E Yeung, A Ng, J Kim, ZZ Sun, RM Murray 53rd IEEE Conference on Decision and Control, 5405-5412, 2014 | 14 | 2014 |
| The Effect of Compositional Context on Synthetic Gene Networks E Yeung, AJ Dy, KB Martin, AH Ng, D Del Vecchio, JL Beck, JJ Collins, ... bioRxiv, 083329, 2016 | 5 | 2016 |
| Analysis of localized cAMP perturbations within a tissue reveal the effects of a local, dynamic gap junction state on ERK signaling JP Fonseca, E Aslankoohi, AH Ng, M Chevalier PLOS Computational Biology 18 (3), e1009873, 2022 | 4 | 2022 |
| Accurate prediction of genetic circuit behavior requires multidimensional characterization of parts G Dods, M Gómez-Schiavon, H El-Samad, AH Ng bioRxiv, 2020.05. 30.122077, 2020 | 4 | 2020 |
| Competitive Displacement of De Novo Designed HeteroDimers Can Reversibly Control Protein–Protein Interactions and Implement Feedback in Synthetic Circuits TH Nguyen, G Dods, M Gómez-Schiavon, M Wu, Z Chen, R Kibler, ... GEN Biotechnology 1 (1), 91-100, 2022 | 3 | 2022 |
| A degron-based bioPROTAC for controlling signaling in CAR T cells M Kim University of California, San Francisco, 2023 | 1 | 2023 |
| Caged-degron-based molecular feedback circuits and methods of using the same D Baker, S Boyken, ELS Hana, M Lajoie, R Langan, A Ng US Patent App. 17/419,236, 2022 | 1 | 2022 |
| De novo design of protein switches for tunable control of protein degradation R Langan, A Ng, S Boyken, M Lajoie, ELS Hana, D Baker US Patent App. 17/419,413, 2022 | 1 | 2022 |
| Synthetic transcriptional synergy AH Ng, H El-Samad Science 364 (6440), 531-532, 2019 | 1 | 2019 |
| Controlling cellular behavior using feed-forward circuits A Westbrook, AH Ng, ELS Hana US Patent App. 18/034,045, 2023 | | 2023 |
Hana El-SamadUniveresity of California, San FranciscoEmail confirmado em ucsf.edu
