Christine A. Iacobuzio-Donahue
Christine A. Iacobuzio-Donahue
Verified email at mskcc.org - Homepage
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Year
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
37322008
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ...
Science 324 (5933), 1457-1461, 2009
26632009
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
S Yachida, S Jones, I Bozic, T Antal, R Leary, B Fu, M Kamiyama, ...
Nature 467 (7319), 1114-1117, 2010
22292010
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ...
cell 144 (1), 27-40, 2011
18742011
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ...
Nature 475 (7354), 106-109, 2011
1737*2011
A draft map of the human proteome
MS Kim, SM Pinto, D Getnet, RS Nirujogi, SS Manda, R Chaerkady, ...
Nature 509 (7502), 575-581, 2014
17162014
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
15352012
Whole genomes redefine the mutational landscape of pancreatic cancer
N Waddell, M Pajic, AM Patch, DK Chang, KS Kassahn, P Bailey, ...
Nature 518 (7540), 495-501, 2015
15172015
Genomic analyses identify molecular subtypes of pancreatic cancer
P Bailey, DK Chang, K Nones, AL Johns, AM Patch, MC Gingras, ...
Nature 531 (7592), 47-52, 2016
14742016
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
PJ Campbell, S Yachida, LJ Mudie, PJ Stephens, ED Pleasance, ...
Nature 467 (7319), 1109-1113, 2010
12562010
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
AD Rhim, PE Oberstein, DH Thomas, ET Mirek, CF Palermo, SA Sastra, ...
Cancer cell 25 (6), 735-747, 2014
11352014
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1-2), 324-338, 2015
9042015
DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer
CA Iacobuzio-Donahue, B Fu, S Yachida, M Luo, H Abe, CM Henderson, ...
Journal of clinical oncology 27 (11), 1806, 2009
8592009
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ...
Science 324 (5924), 217-217, 2009
7782009
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers
G Feldmann, S Dhara, V Fendrich, D Bedja, R Beaty, M Mullendore, ...
Cancer research 67 (5), 2187-2196, 2007
7722007
Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis
Y Miyamoto, A Maitra, B Ghosh, U Zechner, P Argani, ...
Cancer cell 3 (6), 565-576, 2003
7382003
Virtual microdissection identifies distinct tumor-and stroma-specific subtypes of pancreatic ductal adenocarcinoma
RA Moffitt, R Marayati, EL Flate, KE Volmar, SGH Loeza, KA Hoadley, ...
Nature genetics 47 (10), 1168, 2015
7242015
Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression
RE Wilentz, CA Iacobuzio-Donahue, P Argani, DM McCarthy, JL Parsons, ...
Cancer research 60 (7), 2002-2006, 2000
6932000
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene …
P Argani, C Iacobuzio-Donahue, B Ryu, C Rosty, M Goggins, RE Wilentz, ...
Clinical cancer research 7 (12), 3862-3868, 2001
5912001
Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease
G He, W Luo, P Li, C Remmers, WJ Netzer, J Hendrick, K Bettayeb, ...
Nature 467 (7311), 95-98, 2010
555*2010
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