John Reichard
John Reichard
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Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1
JF Reichard, GT Motz, A Puga
Nucleic acids research 35 (21), 7074-7086, 2007
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
Effects of arsenic exposure on DNA methylation and epigenetic gene regulation
JF Reichard, A Puga
Epigenomics 2 (1), 87-104, 2010
Long term low-dose arsenic exposure induces loss of DNA methylation
JF Reichard, M Schnekenburger, A Puga
Biochemical and biophysical research communications 352 (1), 188-192, 2007
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data
A Koleti, R Terryn, V Stathias, C Chung, DJ Cooper, JP Turner, D Vidović, ...
Nucleic acids research 46 (D1), D558-D566, 2018
4-Hydroxynonenal and malondialdehyde hepatic protein adducts in rats treated with carbon tetrachloride: immunochemical detection and lobular localization
DP Hartley, KL Kolaja, J Reichard, DR Petersen
Toxicology and applied pharmacology 161 (1), 23-33, 1999
Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs
MA Sartor, M Schnekenburger, JL Marlowe, JF Reichard, Y Wang, Y Fan, ...
Environmental Health Perspectives 117 (7), 1139-1146, 2009
Arsenic toxicology: translating between experimental models and human pathology
JC States, A Barchowsky, IL Cartwright, JF Reichard, BW Futscher, ...
Environmental health perspectives 119 (10), 1356-1363, 2011
BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite
JF Reichard, MA Sartor, A Puga
Journal of biological chemistry 283 (33), 22363-22370, 2008
Mode of action and dose–response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study
RA Budinsky, D Schrenk, T Simon, M Van den Berg, JF Reichard, ...
Critical reviews in toxicology 44 (1), 83-119, 2014
Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes
S Kann, M Huang, C Estes, JF Reichard, MA Sartor, Y Xia, A Puga
Molecular pharmacology 68 (2), 336-346, 2005
Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor
JF Reichard, TP Dalton, HG Shertzer, A Puga
Dose-Response 3 (3), dose-response. 003.03. 003, 2005
Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status
S Kann, C Estes, JF Reichard, M Huang, MA Sartor, S Schwemberger, ...
Toxicological sciences 87 (2), 365-384, 2005
Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver
JF Reichard, V Vasiliou, DR Petersen
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2000
Toxicokinetic and toxicodynamic considerations when deriving health-based exposure limits for pharmaceuticals
JF Reichard, MA Maier, BD Naumann, AM Pecquet, T Pfister, R Sandhu, ...
Regulatory Toxicology and Pharmacology 79, S67-S78, 2016
Connecting omics signatures of diseases, drugs, and mechanisms of actions with iLINCS
M Pilarczyk, M Kouril, B Shamsaei, J Vasiliauskas, W Niu, N Mahi, ...
BioRxiv, 826271, 2019
Connecting omics signatures and revealing biological mechanisms with iLINCS
M Pilarczyk, M Fazel-Najafabadi, M Kouril, B Shamsaei, J Vasiliauskas, ...
Nature communications 13 (1), 4678, 2022
Genome-wide signatures of transcription factor activity: connecting transcription factors, disease, and small molecules
J Chen, Z Hu, M Phatak, J Reichard, JM Freudenberg, S Sivaganesan, ...
PLoS computational biology 9 (9), e1003198, 2013
Characterization of multidrug resistance-associated protein 2 in the hepatocellular disposition of 4-hydroxynonenal
JF Reichard, JA Doorn, F Simon, MS Taylor, DR Petersen
Archives of biochemistry and biophysics 411 (2), 243-250, 2003
Update: Mode of action (MOA) for liver tumors induced by oral exposure to 1, 4-dioxane
ML Dourson, J Higginbotham, J Crum, H Burleigh-Flayer, P Nance, ...
Regulatory Toxicology and Pharmacology 88, 45-55, 2017
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