| Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives L Baldi, DL Hacker, M Adam, FM Wurm Biotechnology letters 29, 677-684, 2007 | 385 | 2007 |
| Critical Role for Lysines 21 and 22 in Signal-induced, Ubiquitin-mediated Proteolysis of IkB-α (∗) L Baldi, K Brown, G Franzoso, U Siebenlist Journal of Biological Chemistry 271 (1), 376-379, 1996 | 278 | 1996 |
| CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56lck Complexes A Arcaro, C Grégoire, TR Bakker, L Baldi, M Jordan, L Goffin, ... The Journal of experimental medicine 194 (10), 1485-1495, 2001 | 257 | 2001 |
| Transient gene expression in suspension HEK‐293 cells: application to large‐scale protein production L Baldi, N Muller, S Picasso, R Jacquet, P Girard, HP Thanh, E Derow, ... Biotechnology progress 21 (1), 148-153, 2005 | 184 | 2005 |
| Recombinant therapeutic protein production in cultivated mammalian cells: current status and future prospects M Matasci, DL Hacker, L Baldi, FM Wurm Drug discovery today: technologies 5 (2-3), e37-e42, 2008 | 153 | 2008 |
| DNA delivery with hyperbranched polylysine: A comparative study with linear and dendritic polylysine Z Kadlecova, Y Rajendra, M Matasci, L Baldi, DL Hacker, FM Wurm, ... Journal of controlled release 169 (3), 276-288, 2013 | 136 | 2013 |
| A simple high-yielding process for transient gene expression in CHO cells Y Rajendra, D Kiseljak, L Baldi, DL Hacker, FM Wurm Journal of biotechnology 153 (1-2), 22-26, 2011 | 128 | 2011 |
| Comparative study on the in vitro cytotoxicity of linear, dendritic, and hyperbranched polylysine analogues Z Kadlecova, L Baldi, D Hacker, FM Wurm, HA Klok Biomacromolecules 13 (10), 3127-3137, 2012 | 126 | 2012 |
| The PiggyBac transposon enhances the frequency of CHO stable cell line generation and yields recombinant lines with superior productivity and stability M Matasci, L Baldi, DL Hacker, FM Wurm Biotechnology and bioengineering 108 (9), 2141-2150, 2011 | 123 | 2011 |
| Sustained activation and tumor targeting of NKT cells using a CD1d–anti-HER2–scFv fusion protein induce antitumor effects in mice K Stirnemann, JF Romero, L Baldi, B Robert, V Cesson, GS Besra, ... The Journal of clinical investigation 118 (3), 994-1005, 2008 | 101 | 2008 |
| Valproic acid enhances recombinant mRNA and protein levels in transiently transfected Chinese hamster ovary cells S Wulhfard, L Baldi, DL Hacker, F Wurm Journal of biotechnology 148 (2-3), 128-132, 2010 | 93 | 2010 |
| Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells DL Hacker, D Kiseljak, Y Rajendra, S Thurnheer, L Baldi, FM Wurm Protein expression and purification 92 (1), 67-76, 2013 | 90 | 2013 |
| Specific recognition of the viral protein UL18 by CD85j/LIR-1/ILT2 on CD8+ T cells mediates the non-MHC-restricted lysis of human cytomegalovirus-infected cells D Saverino, F Ghiotto, A Merlo, S Bruno, L Battini, M Occhino, M Maffei, ... The Journal of Immunology 172 (9), 5629-5637, 2004 | 80 | 2004 |
| The signal response of IκBα is regulated by transferable N-and C-terminal domains K Brown, G Franzoso, L Baldi, L Carlson, L Mills, YC Lin, S Gerstberger, ... Molecular and cellular biology, 1997 | 64 | 1997 |
| Comparison of three transposons for the generation of highly productive recombinant CHO cell pools and cell lines S Balasubramanian, Y Rajendra, L Baldi, DL Hacker, FM Wurm Biotechnology and bioengineering 113 (6), 1234-1243, 2016 | 63 | 2016 |
| High-titer, serum-free production of adeno-associated virus vectors by polyethyleneimine-mediated plasmid transfection in mammalian suspension cells M Hildinger, L Baldi, M Stettler, FM Wurm Biotechnology letters 29, 1713-1721, 2007 | 60 | 2007 |
| Rapid recombinant protein production from piggyBac transposon-mediated stable CHO cell pools S Balasubramanian, M Matasci, Z Kadlecova, L Baldi, DL Hacker, ... Journal of biotechnology 200, 61-69, 2015 | 59 | 2015 |
| Natural anti-FcεRIα autoantibodies may interfere with diagnostic tests for autoimmune urticaria JM Pachlopnik, MP Horn, M Fux, M Dahinden, M Mandallaz, ... Journal of autoimmunity 22 (1), 43-51, 2004 | 51 | 2004 |
| Innovative, non-stirred bioreactors in scales from milliliters up to 1000 liters for suspension cultures of cells using disposable bags and containers–a Swiss contribution S Werner, D Hacker, L Baldi, R Tanner, M Kühner, G Broccard, C Bürkie, ... Chimia 64 (11), 819-819, 2010 | 50 | 2010 |
| Role of non‐specific DNA in reducing coding DNA requirement for transient gene expression with CHO and HEK‐293E cells Y Rajendra, D Kiseljak, S Manoli, L Baldi, DL Hacker, FM Wurm Biotechnology and bioengineering 109 (9), 2271-2278, 2012 | 46 | 2012 |
F.M. WurmSwiss Federal Institute of Technology Lausanne (EPFL)Email confirmado em epfl.ch
