Robert B Darnell
Robert B Darnell
Professor, Rockefeller University; Investigator, HHMI; Founding Director, NY Genome Center
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FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
JC Darnell, SJ Van Driesche, C Zhang, KYS Hung, A Mele, CE Fraser, ...
Cell 146 (2), 247-261, 2011
Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps
SW Chi, JB Zang, A Mele, RB Darnell
Nature 460 (7254), 479-486, 2009
De novo gene disruptions in children on the autistic spectrum
I Iossifov, M Ronemus, D Levy, Z Wang, I Hakker, J Rosenbaum, ...
Neuron 74 (2), 285-299, 2012
HITS-CLIP yields genome-wide insights into brain alternative RNA processing
DD Licatalosi, A Mele, JJ Fak, J Ule, M Kayikci, SW Chi, TA Clark, ...
Nature 456 (7221), 464-469, 2008
Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome
V Brown, P Jin, S Ceman, JC Darnell, WT O'Donnell, SA Tenenbaum, ...
Cell 107 (4), 477-487, 2001
CLIP identifies Nova-regulated RNA networks in the brain
J Ule, KB Jensen, M Ruggiu, A Mele, A Ule, RB Darnell
Science 302 (5648), 1212-1215, 2003
Paraneoplastic syndromes involving the nervous system
RB Darnell, JB Posner
New England Journal of Medicine 349 (16), 1543-1554, 2003
A call for transparent reporting to optimize the predictive value of preclinical research
SC Landis, SG Amara, K Asadullah, CP Austin, R Blumenstein, ...
Nature 490 (7419), 187-191, 2012
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
JC Darnell, KB Jensen, P Jin, V Brown, ST Warren, RB Darnell
Cell 107 (4), 489-499, 2001
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
H Fei, HJ Okano, C Li, GH Lee, C Zhao, R Darnell, JM Friedman
Proceedings of the National Academy of Sciences 94 (13), 7001-7005, 1997
RNA processing and its regulation: global insights into biological networks
DD Licatalosi, RB Darnell
Nature Reviews Genetics 11 (1), 75-87, 2010
A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
S Ke, EA Alemu, C Mertens, EC Gantman, JJ Fak, A Mele, B Haripal, ...
Genes & development 29 (19), 2037-2053, 2015
Vaccine breakthrough infections with SARS-CoV-2 variants
E Hacisuleyman, C Hale, Y Saito, NE Blachere, M Bergh, EG Conlon, ...
New England Journal of Medicine 384 (23), 2212-2218, 2021
CLIP: a method for identifying protein–RNA interaction sites in living cells
J Ule, K Jensen, A Mele, RB Darnell
Methods 37 (4), 376-386, 2005
An RNA map predicting Nova-dependent splicing regulation
J Ule, G Stefani, A Mele, M Ruggiu, X Wang, B Taneri, T Gaasterland, ...
Nature 444 (7119), 580-586, 2006
Nova regulates brain-specific splicing to shape the synapse
J Ule, A Ule, J Spencer, A Williams, JS Hu, M Cline, H Wang, T Clark, ...
Nature genetics 37 (8), 844-852, 2005
Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells
ML Albert, M Jegathesan, RB Darnell
Nature immunology 2 (11), 1010-1017, 2001
Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability
KB Jensen, BK Dredge, G Stefani, R Zhong, RJ Buckanovich, HJ Okano, ...
Neuron 25 (2), 359-371, 2000
Tumor-specific killer cells in paraneoplastic cerebellar degeneration
ML Albert, JC Darnell, A Bender, LM Francisco, N Bhardwaj, RB Darnell
Nature medicine 4 (11), 1321-1324, 1998
Assembly and diploid architecture of an individual human genome via single-molecule technologies
M Pendleton, R Sebra, AWC Pang, A Ummat, O Franzen, T Rausch, ...
Nature methods 12 (8), 780-786, 2015
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