Luca Pellegrini
Luca Pellegrini
Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK
Verified email at cam.ac.uk - Homepage
TitleCited byYear
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin
L Pellegrini, DF Burke, F von Delft, B Mulloy, TL Blundell
Nature 407 (6807), 1029, 2000
7922000
Insights into DNA recombination from the structure of a RAD51–BRCA2 complex
L Pellegrini, SY David, T Lo, S Anand, MY Lee, TL Blundell, ...
Nature 420 (6913), 287, 2002
6892002
Structure of serum response factor core bound to DNA
L Pellegrini, S Tan, TJ Richmond
Nature 376 (6540), 490, 1995
3691995
Role of heparan sulfate in fibroblast growth factor signalling: a structural view
L Pellegrini
Current opinion in structural biology 11 (5), 629-634, 2001
3252001
Crystal structure of an Xrcc4–DNA ligase IV complex
BL Sibanda, SE Critchlow, J Begun, XY Pei, SP Jackson, TL Blundell, ...
Nature Structural & Molecular Biology 8 (12), 1015-1019, 2001
2822001
Full‐length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2
DS Shin, L Pellegrini, DS Daniels, B Yelent, L Craig, D Bates, SY David, ...
The EMBO journal 22 (17), 4566-4576, 2003
2732003
Interaction with the BRCA2 C terminus protects RAD51–DNA filaments from disassembly by BRC repeats
OR Davies, L Pellegrini
Nature structural & molecular biology 14 (6), 475, 2007
1782007
An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis
S Klinge, J Hirst, JD Maman, T Krude, L Pellegrini
Nature structural & molecular biology 14 (9), 875, 2007
1532007
The Crystal Structure of Fibroblast Growth Factor (FGF) 19 Reveals Novel Features of the FGF Family and Offers a Structural Basis for Its Unusual Receptor Affinity,
NJ Harmer, L Pellegrini, D Chirgadze, J Fernandez-Recio, TL Blundell
Biochemistry 43 (3), 629-640, 2004
1452004
A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome
AC Simon, JC Zhou, RL Perera, F van Deursen, C Evrin, ME Ivanova, ...
Nature 510 (7504), 293, 2014
1242014
Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2
SY David, E Sonoda, S Takeda, CLH Huang, L Pellegrini, TL Blundell, ...
Molecular cell 12 (4), 1029-1041, 2003
1242003
Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)–FGF receptor–heparin complex
NJ Harmer, LL Ilag, B Mulloy, L Pellegrini, CV Robinson, TL Blundell
Journal of molecular biology 339 (4), 821-834, 2004
1192004
Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer
T Lo, L Pellegrini, AR Venkitaraman, TL Blundell
DNA repair 2 (9), 1015-1028, 2003
1182003
3D architecture of DNA Pol α reveals the functional core of multi‐subunit replicative polymerases
S Klinge, R Núñez‐Ramírez, O Llorca, L Pellegrini
The EMBO Journal 28 (13), 1978-1987, 2009
942009
Emerging functions of BRCA2 in DNA recombination
L Pellegrini, A Venkitaraman
Trends in biochemical sciences 29 (6), 310-316, 2004
932004
Smarcal1-mediated fork reversal triggers Mre11-dependent degradation of nascent DNA in the absence of Brca2 and stable Rad51 nucleofilaments
AM Kolinjivadi, V Sannino, A De Antoni, K Zadorozhny, M Kilkenny, ...
Molecular cell 67 (5), 867-881. e7, 2017
892017
A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange
MKK Shivji, OR Davies, JM Savill, DL Bates, L Pellegrini, ...
Nucleic acids research 34 (14), 4000-4011, 2006
782006
Structure of an Xrcc4–DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode
AS Doré, N Furnham, OR Davies, BL Sibanda, DY Chirgadze, ...
DNA repair 5 (3), 362-368, 2006
772006
Structure of the heterodimeric core primase
SH Lao-Sirieix, RK Nookala, P Roversi, SD Bell, L Pellegrini
Nature structural & molecular biology 12 (12), 1137, 2005
692005
A molecular model for the role of SYCP3 in meiotic chromosome organisation
JL Syrjänen, L Pellegrini, OR Davies
Elife 3, e02963, 2014
682014
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Articles 1–20