| Rational design of α-helical antimicrobial peptides with enhanced activities and specificity/therapeutic index Y Chen, CT Mant, SW Farmer, REW Hancock, ML Vasil, RS Hodges Journal of biological chemistry 280 (13), 12316-12329, 2005 | 697 | 2005 |
| Interactions of Bacterial Cationic Peptide Antibiotics with Outer and Cytoplasmic Membranes ofPseudomonas aeruginosa L Zhang, P Dhillon, H Yan, S Farmer, REW Hancock Antimicrobial agents and chemotherapy 44 (12), 3317-3321, 2000 | 427 | 2000 |
| Dissociation of antimicrobial and hemolytic activities in cyclic peptide diastereomers by systematic alterations in amphipathicity LH Kondejewski, M Jelokhani-Niaraki, SW Farmer, B Lix, CM Kay, ... Journal of Biological Chemistry 274 (19), 13181-13192, 1999 | 307 | 1999 |
| Screening and characterization of surface-tethered cationic peptides for antimicrobial activity K Hilpert, M Elliott, H Jenssen, J Kindrachuk, CD Fjell, J Körner, ... Chemistry & biology 16 (1), 58-69, 2009 | 273 | 2009 |
| Interaction of aminoglycosides with the outer membranes and purified lipopolysaccharide and OmpF porin of Escherichia coli RE Hancock, SW Farmer, ZS Li, K Poole Antimicrobial agents and chemotherapy 35 (7), 1309-1314, 1991 | 241 | 1991 |
| Antimicrobial constituents of Rhus glabra G Saxena, AR McCutcheon, S Farmer, GHN Towers, REW Hancock Journal of ethnopharmacology 42 (2), 95-99, 1994 | 238 | 1994 |
| Gramicidin S is active against both gram‐positive and gram‐negative bacteria LH Kondejewski, SW Farmer, DS Wishart, REW HANCOCK, RS Hodges International journal of peptide and protein research 47 (6), 460-466, 1996 | 226 | 1996 |
| Modulation of structure and antibacterial and hemolytic activity by ring size in cyclic gramicidin S analogs LH Kondejewski, SW Farmer, DS Wishart, CM Kay, REW Hancock, ... Journal of Biological Chemistry 271 (41), 25261-25268, 1996 | 218 | 1996 |
| Antibacterial and antifungal polyine compounds from Glehnia littoralis ssp. leiocarpa H Matsuura, G Saxena, SW Farmer, REW Hancock, GHN Towers Planta medica 62 (03), 256-259, 1996 | 128 | 1996 |
| Conversion of Pseudomonas aeruginosa to the phenotype characteristic of strains from patients with cystic fibrosis DP Speert, SW Farmer, ME Campbell, JM Musser, RK Selander, S Kuo Journal of clinical microbiology 28 (2), 188-194, 1990 | 119 | 1990 |
| Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures A Baghela, OM Pena, AH Lee, B Baquir, R Falsafi, A An, SW Farmer, ... EBioMedicine 75, 2022 | 107 | 2022 |
| Use of specific dyes in the detection of antimicrobial compounds from crude plant extracts using a thin layer chromatography agar overlay technique G Saxena, S Farmer, GHN Towers, REW Hancock Phytochemical analysis 6 (3), 125-129, 1995 | 100 | 1995 |
| Optimization of microbial specificity in cyclic peptides by modulation of hydrophobicity within a defined structural framework LH Kondejewski, DL Lee, M Jelokhani-Niaraki, SW Farmer, ... Journal of Biological Chemistry 277 (1), 67-74, 2002 | 96 | 2002 |
| Diastereoisomeric analogues of gramicidin S: structure, biological activity and interaction with lipid bilayers M Jelokhani-Niaraki, LH Kondejewski, SW Farmer, REW Hancock, ... Biochemical Journal 349 (3), 747-755, 2000 | 82 | 2000 |
| Influence of outer membrane mutations on susceptibility of Escherichia coli to the dibasic macrolide azithromycin S Farmer, Z Li, REW Hancock Journal of Antimicrobial Chemotherapy 29 (1), 27-33, 1992 | 81 | 1992 |
| Use of a pilin gene probe to study molecular epidemiology of Pseudomonas aeruginosa DP Speert, ME Campbell, SW Farmer, K Volpel, AM Joffe, W Paranchych Journal of clinical microbiology 27 (11), 2589-2593, 1989 | 72 | 1989 |
| Interaction of cationic peptides with bacterial membranes S Fidai, SW Farmer, REW Hancock Antibacterial Peptide Protocols, 187-204, 1997 | 59 | 1997 |
| Mechanism of uptake of deglucoteicoplanin amide derivatives across outer membranes of Escherichia coli and Pseudomonas aeruginosa RE Hancock, SW Farmer Antimicrobial agents and chemotherapy 37 (3), 453-456, 1993 | 58 | 1993 |
| Antimicrobial compounds from Alnus rubra G Saxena, S Farmer, REW Hancock, GHN Towers International journal of pharmacognosy 33 (1), 33-36, 1995 | 56 | 1995 |
| Purification and partial characterization of the OmpA family of proteins of Pasteurella haemolytica PJ Mahasreshti, GL Murphy, JH Wyckoff 3rd, S Farmer, RE Hancock, ... Infection and immunity 65 (1), 211-218, 1997 | 49 | 1997 |
Robert E. W. HancockUniversity of British ColumbiaVerified email at hancocklab.com
