BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem, ... Nature, 2015 | 904 | 2015 |
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level DE Bauer, SC Kamran, S Lessard, J Xu, Y Fujiwara, C Lin, Z Shao, ... Science 342 (6155), 253-257, 2013 | 667 | 2013 |
Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes Y Gao, E Smith, E Ker, P Campbell, E Cheng, S Zou, S Lin, L Wang, ... Developmental cell 22 (3), 573-584, 2012 | 100 | 2012 |
ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets LA Truman, KL Bentley, EC Smith, SA Massaro, DG Gonzalez, ... The American journal of pathology 180 (4), 1715-1725, 2012 | 96 | 2012 |
Chronic myelogenous leukemia–initiating cells require Polycomb group protein EZH2 H Xie, C Peng, J Huang, BE Li, W Kim, EC Smith, Y Fujiwara, J Qi, ... Cancer Discovery 6 (11), 1237-1247, 2016 | 89 | 2016 |
MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation EC Smith, JN Thon, MT Devine, S Lin, VP Schulz, Y Guo, SA Massaro, ... Blood 120 (11), 2317-2329, 2012 | 72 | 2012 |
Myocardin Related Transcription Factors Promote Megakaryocyte Maturation and Platelet Formation EC Smith YALE UNIVERSITY, 2012 | 70* | 2012 |
Hemoglobin genetics: recent contributions of GWAS and gene editing EC Smith, SH Orkin Human Molecular Genetics, ddw170, 2016 | 53 | 2016 |
Induction of megakaryocyte differentiation drives nuclear accumulation and transcriptional function of MKL1 via actin polymerization and RhoA activation EC Smith, AM Teixeira, RC Chen, L Wang, Y Gao, KL Hahn, DS Krause Blood 121 (7), 1094-1101, 2013 | 49 | 2013 |
Strict in vivo specificity of the Bcl11a erythroid enhancer EC Smith, S Luc, DM Croney, MB Woodworth, LC Greig, Y Fujiwara, ... Blood 128 (19), 2338-2342, 2016 | 46 | 2016 |
Hinge residue I174 is critical for proper dNTP selection by DNA polymerase β J Yamtich, D Starcevic, J Lauper, E Smith, I Shi, S Rangarajan, J Jaeger, ... Biochemistry 49 (11), 2326-2334, 2010 | 32 | 2010 |
Crispr-Cas9 Saturating Mutagenesis Reveals an Achilles Heel in the BCL11A Erythroid Enhancer for Fetal Hemoglobin Induction (by Genome Editing) DE Bauer, MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, ... Blood 126 (23), 638-638, 2015 | 7 | 2015 |
Identification of BCL11A structure-function domains for fetal hemoglobin silencing DE Bauer, C Peng, EC Smith, SH Orkin Blood 122 (21), 435-435, 2013 | 4 | 2013 |
Fine-Mapping and Genome Editing Reveal An Essential Erythroid Enhancer At The HbF-Associated BCL11A Locus SC Kamran, S Lessard, J Xu, Y Fujiwara, C Lin, Z Shao, MC Canver, ... Blood 122 (21), 437-437, 2013 | 2 | 2013 |
HHS Public Access MC Canver, EC Smith, F Sher, L Pinello, NE Sanjana, O Shalem Nature 527 (7577), 192-197, 2015 | | 2015 |
MKL2 Functions in the Absence of MKL1 to Promote Megakaryocyte Maturation EC Smith, JN Thon, SA Massaro, JE Italiano, D Krause Blood 118 (21), 2336-2336, 2011 | | 2011 |
Modeling Megakaryopoiesis and Leukemogenesis Using Human and Murine Embryonic Stem Cells SA Massaro, EC Smith, M Iacovino, M Kyba, D Krause Blood 116 (21), 2502-2502, 2010 | | 2010 |
Serum Response Factor Is An Essential Transcription Factor in Megakaryocytic Maturation. S Halene, Y Gao, K Hahn, E Smith, S Lin, AS Perkins, D Krause Blood 114 (22), 3652-3652, 2009 | | 2009 |