Ma. Xenia G. Ilagan
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The canonical Notch signaling pathway: unfolding the activation mechanism
R Kopan, MXG Ilagan
Cell 137 (2), 216-233, 2009
30192009
γ-Secretase: proteasome of the membrane?
R Kopan, MXG Ilagan
Nature reviews Molecular cell biology 5 (6), 499-504, 2004
6482004
A presenilin dimer at the core of the γ-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis
EH Schroeter, MXG Ilagan, AL Brunkan, S Hecimovic, Y Li, M Xu, ...
Proceedings of the National Academy of Sciences 100 (22), 13075-13080, 2003
2562003
SnapShot: notch signaling pathway
MXG Ilagan, R Kopan
Cell 128 (6), 1246. e1-1246. e2, 2007
1732007
Analysis of Notch function in presomitic mesoderm suggests a γ-secretase-independent role for presenilins in somite differentiation
SS Huppert, MXG Ilagan, B De Strooper, R Kopan
Developmental cell 8 (5), 677-688, 2005
1592005
Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes
KL Arnett, M Hass, DG McArthur, MXG Ilagan, JC Aster, R Kopan, ...
Nature structural & molecular biology 17 (11), 1312, 2010
1172010
γ-Secretase composed of PS1/Pen2/Aph1a can cleave notch and amyloid precursor protein in the absence of nicastrin
G Zhao, Z Liu, MXG Ilagan, R Kopan
Journal of Neuroscience 30 (5), 1648-1656, 2010
1112010
Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2
JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao, AS Kim, LM Bloyet, ...
Cell host & microbe 28 (3), 475-485. e5, 2020
1072020
Quantitative dissection of the Notch: CSL interaction: insights into the Notch-mediated transcriptional switch
OY Lubman, MXG Ilagan, R Kopan, D Barrick
Journal of molecular biology 365 (3), 577-589, 2007
1032007
Real-time imaging of notch activation with a luciferase complementation-based reporter
MXG Ilagan, S Lim, M Fulbright, D Piwnica-Worms, R Kopan
Science signaling 4 (181), rs7-rs7, 2011
812011
The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development
Z Liu, S Chen, S Boyle, Y Zhu, A Zhang, DR Piwnica-Worms, MXG Ilagan, ...
Developmental cell 25 (6), 585-598, 2013
732013
An overview of notch signaling in adult tissue renewal and maintenance
C Sato, G Zhao, XG Ilagan
Current Alzheimer Research 9 (2), 227-240, 2012
502012
Structural analysis uncovers lipid-binding properties of Notch ligands
CR Chillakuri, D Sheppard, MXG Ilagan, LR Holt, F Abbott, S Liang, ...
Cell reports 5 (4), 861-867, 2013
442013
Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor
KS Yang, MXG Ilagan, D Piwnica-Worms, LJ Pike
Journal of Biological Chemistry 284 (12), 7474-7482, 2009
442009
Thermodynamic analysis of the CSL· Notch interaction: distribution of binding energy of the Notch RAM region to the CSL β-trefoil domain and the mode of competition with the …
SE Johnson, MXG Ilagan, R Kopan, D Barrick
Journal of Biological Chemistry 285 (9), 6681-6692, 2010
432010
Differential developmental expression and cell type specificity of Dictyostelium catalases and their response to oxidative stress and UV-light
MXU Garcia, C Foote, S Van Es, PN Devreotes, S Alexander, H Alexander
Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1492 (2-3 …, 2000
402000
RNF4-dependent oncogene activation by protein stabilization
JJ Thomas, M Abed, J Heuberger, R Novak, Y Zohar, APB Lopez, ...
Cell reports 16 (12), 3388-3400, 2016
322016
Differential developmental expression of the repB and repD Xeroderma pigmentosum related DNA helicase genes from Dictyostelium discoideum
SK Lee, SL Yu, MX Garcia, H Alexander, S Alexander
Nucleic acids research 25 (12), 2365-2374, 1997
271997
The Dictyostelium discoideum prespore-specific catalase B functions to control late development and to protect spore viability
MXU Garcia, H Alexander, D Mahadeo, DA Cotter, S Alexander
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1641 (1), 55-64, 2003
222003
Selective blockade of transport via SERCA inhibition: the answer for oncogenic forms of Notch?
MXG Ilagan, R Kopan
Cancer cell 23 (3), 267-269, 2013
202013
O sistema não pode efectuar a operação agora. Tente novamente mais tarde.
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