Follow
Daniel Czyzyk
Daniel Czyzyk
Yale University
Verified email at wesleyan.edu
Title
Cited by
Cited by
Year
Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory reponses after antecedent hypoglycemia
O Chan, H Cheng, R Herzog, D Czyzyk, W Zhu, A Wang, RJ McCrimmon, ...
Diabetes 57 (5), 1363-1370, 2008
1172008
Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia
W Zhu, D Czyzyk, SA Paranjape, L Zhou, A Horblitt, G Szabó, ...
American Journal of Physiology-Endocrinology and Metabolism 298 (5), E971-E977, 2010
712010
Increased GABAergic output in the ventromedial hypothalamus contributes to impaired hypoglycemic counterregulation in diabetic rats
O Chan, S Paranjape, D Czyzyk, A Horblitt, W Zhu, Y Ding, X Fan, ...
Diabetes 60 (5), 1582-1589, 2011
692011
Lipopolysaccharide Biosynthesis without the Lipids: Recognition Promiscuity of Escherichia coli Heptosyltransferase I
DJ Czyzyk, C Liu, EA Taylor
Biochemistry 50 (49), 10570-10572, 2011
282011
The Stories Tryptophans Tell: Exploring Protein Dynamics of Heptosyltransferase I from Escherichia coli
JM Cote, CA Ramirez-Mondragon, ZS Siegel, DJ Czyzyk, J Gao, ...
Biochemistry 56 (6), 886-895, 2017
182017
Escherichia coli Heptosyltransferase I: Investigation of Protein Dynamics of a GT-B Structural Enzyme
DJ Czyzyk, SS Sawant, CA Ramirez-Mondragon, MM Hingorani, ...
Biochemistry 52 (31), 5158-5160, 2013
172013
A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium
A Mukerjee, P Iyidogan, A Cstellanos-Gonzalez, A Cisneros, Jose, ...
Bioorganic & Medicinal Chemistry Letters 25 (10), 2065-2067, 2015
162015
Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors
DJ Czyzyk, M Valhondo, L Deiana, J Tirado-Rives, WL Jorgensen, ...
European journal of medicinal chemistry 183, 111673, 2019
92019
Synthesis, kinetics and inhibition of Escherichia coli Heptosyltransferase I by monosaccharide analogues of Lipid A
NK Nkosana, DJ Czyzyk, ZS Siegel, JM Cote, EA Taylor
Bioorganic & medicinal chemistry letters 28 (4), 594-600, 2018
92018
Novel allosteric covalent inhibitors of bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa identified by virtual screening
V Ruiz, DJ Czyzyk, M Valhondo, WL Jorgensen, KS Anderson
Bioorganic & medicinal chemistry letters 29 (11), 1413-1418, 2019
82019
Understanding the structural basis of species selective, stereospecific inhibition for Cryptosporidium and human thymidylate synthase
DJ Czyzyk, M Valhondo, WL Jorgensen, KS Anderson
FEBS letters 593 (15), 2069-2078, 2019
32019
Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitors
VG Ruiz, DJ Czyzyk, VP Kumar, WL Jorgensen, KS Anderson
Bioorganic & medicinal chemistry letters 30 (16), 127292, 2020
22020
Raid of Increased GABAergic Inhibition within the Ventromedial Hypothalamus in the Impaired Counterregulatory Response to Hypoglycemia in Diabetes
O Chan, SA Paranjape, D Czyzyk, M Seashore, W Zhu, Y Ding, X Fan, ...
Diabetes 58, A34-A34, 2009
22009
E. Coli Heptosyltransferase I: Exploring Function and Dynamics to Create Better Inhibitors for GT-B Enzymes
DJ Czyzyk, C Liu, SS Sawant, M Hingorani, EA Taylor
Biophysical Journal 104 (2), 61a, 2013
12013
Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic prot
VG Ruiza, DJ Czyzyk, VP Kumar, WL Jorgensen, KS Anderson
Bioorg. Med. Chem. Lett. 30 (16)), 2020
2020
Escherichia coli Heptosyltransferase I: Examining Protein Dynamics with Pyrene Excimer Fluorescence and Tryptophan‐Induced Quenching
CJS Hecht, JM Cote, DJ Czyzyk, EA Taylor
The FASEB Journal 32, 796.15-796.15, 2018
2018
Escherichia coli Heptosyltransferase I: Exploration of Kinetics and Dynamics of a GT-B Enzyme
DJ Czyzyk
Wesleyan University, 2015
2015
𝘌𝘴𝘤𝘩𝘦𝘳𝘪𝘤𝘩𝘪𝘢 𝘤𝘰𝘭𝘪 Heptosyltransferase I: Exploration of Kinetics and Dynamics of a GT-B Enzyme
DJ Czyzyk
2015
Lipopolysaccharide Biosynthesis Without the Lipids: Substrate Recognition for Escherichia coli HeptosyltransferaseI
DJ Czyzyk, C Liu, EA Taylor
2011
Heptosyltransferase I Lipid a Structure Activity Relationships (SAR)
DJ Czyzyk, EA Taylor
Biophysical Journal 100 (3), 219a, 2011
2011
The system can't perform the operation now. Try again later.
Articles 1–20