Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory reponses after antecedent hypoglycemia O Chan, H Cheng, R Herzog, D Czyzyk, W Zhu, A Wang, RJ McCrimmon, ... Diabetes 57 (5), 1363-1370, 2008 | 117 | 2008 |
Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia W Zhu, D Czyzyk, SA Paranjape, L Zhou, A Horblitt, G Szabó, ... American Journal of Physiology-Endocrinology and Metabolism 298 (5), E971-E977, 2010 | 71 | 2010 |
Increased GABAergic output in the ventromedial hypothalamus contributes to impaired hypoglycemic counterregulation in diabetic rats O Chan, S Paranjape, D Czyzyk, A Horblitt, W Zhu, Y Ding, X Fan, ... Diabetes 60 (5), 1582-1589, 2011 | 69 | 2011 |
Lipopolysaccharide Biosynthesis without the Lipids: Recognition Promiscuity of Escherichia coli Heptosyltransferase I DJ Czyzyk, C Liu, EA Taylor Biochemistry 50 (49), 10570-10572, 2011 | 28 | 2011 |
The Stories Tryptophans Tell: Exploring Protein Dynamics of Heptosyltransferase I from Escherichia coli JM Cote, CA Ramirez-Mondragon, ZS Siegel, DJ Czyzyk, J Gao, ... Biochemistry 56 (6), 886-895, 2017 | 18 | 2017 |
Escherichia coli Heptosyltransferase I: Investigation of Protein Dynamics of a GT-B Structural Enzyme DJ Czyzyk, SS Sawant, CA Ramirez-Mondragon, MM Hingorani, ... Biochemistry 52 (31), 5158-5160, 2013 | 17 | 2013 |
A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium A Mukerjee, P Iyidogan, A Cstellanos-Gonzalez, A Cisneros, Jose, ... Bioorganic & Medicinal Chemistry Letters 25 (10), 2065-2067, 2015 | 16 | 2015 |
Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors DJ Czyzyk, M Valhondo, L Deiana, J Tirado-Rives, WL Jorgensen, ... European journal of medicinal chemistry 183, 111673, 2019 | 9 | 2019 |
Synthesis, kinetics and inhibition of Escherichia coli Heptosyltransferase I by monosaccharide analogues of Lipid A NK Nkosana, DJ Czyzyk, ZS Siegel, JM Cote, EA Taylor Bioorganic & medicinal chemistry letters 28 (4), 594-600, 2018 | 9 | 2018 |
Novel allosteric covalent inhibitors of bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa identified by virtual screening V Ruiz, DJ Czyzyk, M Valhondo, WL Jorgensen, KS Anderson Bioorganic & medicinal chemistry letters 29 (11), 1413-1418, 2019 | 8 | 2019 |
Understanding the structural basis of species selective, stereospecific inhibition for Cryptosporidium and human thymidylate synthase DJ Czyzyk, M Valhondo, WL Jorgensen, KS Anderson FEBS letters 593 (15), 2069-2078, 2019 | 3 | 2019 |
Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitors VG Ruiz, DJ Czyzyk, VP Kumar, WL Jorgensen, KS Anderson Bioorganic & medicinal chemistry letters 30 (16), 127292, 2020 | 2 | 2020 |
Raid of Increased GABAergic Inhibition within the Ventromedial Hypothalamus in the Impaired Counterregulatory Response to Hypoglycemia in Diabetes O Chan, SA Paranjape, D Czyzyk, M Seashore, W Zhu, Y Ding, X Fan, ... Diabetes 58, A34-A34, 2009 | 2 | 2009 |
E. Coli Heptosyltransferase I: Exploring Function and Dynamics to Create Better Inhibitors for GT-B Enzymes DJ Czyzyk, C Liu, SS Sawant, M Hingorani, EA Taylor Biophysical Journal 104 (2), 61a, 2013 | 1 | 2013 |
Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic prot VG Ruiza, DJ Czyzyk, VP Kumar, WL Jorgensen, KS Anderson Bioorg. Med. Chem. Lett. 30 (16)), 2020 | | 2020 |
Escherichia coli Heptosyltransferase I: Examining Protein Dynamics with Pyrene Excimer Fluorescence and Tryptophan‐Induced Quenching CJS Hecht, JM Cote, DJ Czyzyk, EA Taylor The FASEB Journal 32, 796.15-796.15, 2018 | | 2018 |
Escherichia coli Heptosyltransferase I: Exploration of Kinetics and Dynamics of a GT-B Enzyme DJ Czyzyk Wesleyan University, 2015 | | 2015 |
𝘌𝘴𝘤𝘩𝘦𝘳𝘪𝘤𝘩𝘪𝘢 𝘤𝘰𝘭𝘪 Heptosyltransferase I: Exploration of Kinetics and Dynamics of a GT-B Enzyme DJ Czyzyk | | 2015 |
Lipopolysaccharide Biosynthesis Without the Lipids: Substrate Recognition for Escherichia coli HeptosyltransferaseI DJ Czyzyk, C Liu, EA Taylor | | 2011 |
Heptosyltransferase I Lipid a Structure Activity Relationships (SAR) DJ Czyzyk, EA Taylor Biophysical Journal 100 (3), 219a, 2011 | | 2011 |