Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate MP Hall, J Unch, BF Binkowski, MP Valley, BL Butler, MG Wood, P Otto, ... ACS chemical biology 7 (11), 1848-1857, 2012 | 1496 | 2012 |
NanoLuc complementation reporter optimized for accurate measurement of protein interactions in cells AS Dixon, MK Schwinn, MP Hall, K Zimmerman, P Otto, TH Lubben, ... ACS chemical biology 11 (2), 400-408, 2016 | 1061 | 2016 |
CRISPR-mediated tagging of endogenous proteins with a luminescent peptide MK Schwinn, T Machleidt, K Zimmerman, CT Eggers, AS Dixon, R Hurst, ... ACS chemical biology 13 (2), 467-474, 2018 | 298 | 2018 |
Novel genetically encoded biosensors using firefly luciferase F Fan, BF Binkowski, BL Butler, PF Stecha, MK Lewis, KV Wood ACS chemical biology 3 (6), 346-351, 2008 | 237 | 2008 |
Correcting errors in synthetic DNA through consensus shuffling BF Binkowski, KE Richmond, J Kaysen, MR Sussman, PJ Belshaw Nucleic acids research 33 (6), e55-e55, 2005 | 144 | 2005 |
A luminescent biosensor with increased dynamic range for intracellular cAMP BF Binkowski, BL Butler, PF Stecha, CT Eggers, P Otto, K Zimmerman, ... ACS chemical biology 6 (11), 1193-1197, 2011 | 124 | 2011 |
Engineered luciferases for molecular sensing in living cells B Binkowski, F Fan, K Wood Current opinion in biotechnology 20 (1), 14-18, 2009 | 101 | 2009 |
Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use B Binkowski, LP Encell, M Hall, MB Robers, MR Slater, KV Wood, ... US Patent 8,669,103, 2014 | 84 | 2014 |
Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate. ACS Chem Biol 7: 1848–1857 MP Hall, J Unch, BF Binkowski, MP Valley, BL Butler, MG Wood, P Otto, ... | 68 | 2012 |
KRAS is vulnerable to reversible switch-II pocket engagement in cells JD Vasta, DM Peacock, Q Zheng, JA Walker, Z Zhang, CA Zimprich, ... Nature chemical biology 18 (6), 596-604, 2022 | 57 | 2022 |
Luminescent biosensors for real-time monitoring of intracellular cAMP BF Binkowski, F Fan, KV Wood Signal Transduction Protocols, 263-271, 2011 | 45 | 2011 |
Real-time detection of CTL function reveals distinct patterns of caspase activation mediated by Fas versus granzyme B J Li, SK Figueira, ACA Vrazo, BF Binkowski, BL Butler, Y Tabata, ... The Journal of Immunology 193 (2), 519-528, 2014 | 43 | 2014 |
Imaging proteolytic activity in live cells and animal models S Galbán, YH Jeon, BM Bowman, J Stevenson, KA Sebolt, LM Sharkey, ... PLoS One 8 (6), e66248, 2013 | 43 | 2013 |
Method of error reduction in nucleic acid populations PJ Belshaw, MR Sussman, F Cerrina, JH Kaysen, BF Binkowski, ... US Patent 7,820,412, 2010 | 38 | 2010 |
Permuted and nonpermuted luciferase biosensors B Binkowski, F Fan, S Wigdal, KV Wood, MG Wood US Patent 9,359,635, 2016 | 33 | 2016 |
Solid‐Phase Synthesis of Dihydrovirginiamycin S1, a Streptogramin B Antibiotic A Shaginian, MC Rosen, BF Binkowski, PJ Belshaw Chemistry–A European Journal 10 (17), 4334-4340, 2004 | 31 | 2004 |
Three efficient methods for preparation of coelenterazine analogues A Shakhmin, MP Hall, JR Walker, T Machleidt, BF Binkowski, KV Wood, ... Chemistry–A European Journal 22 (30), 10369-10375, 2016 | 30 | 2016 |
Live cell evaluation of granzyme delivery and death receptor signaling in tumor cells targeted by human natural killer cells AC Vrazo, AE Hontz, SK Figueira, BL Butler, JM Ferrell, BF Binkowski, J Li, ... Blood, The Journal of the American Society of Hematology 126 (8), e1-e10, 2015 | 28 | 2015 |
Mutant protease biosensors with enhanced detection characteristics B Binkowski, B Butler, LP Encell, F Fan, H Brad, P Otto, G Vidugiris, ... US Patent 8,735,559, 2014 | 27 | 2014 |
Spatial photorelease of oligonucleotides, using a safety-catch photolabile linker ST Flickinger, M Patel, BF Binkowski, AM Lowe, MH Li, C Kim, F Cerrina, ... Organic Letters 8 (11), 2357-2360, 2006 | 26 | 2006 |