| Purified Argonaute2 and an siRNA form recombinant human RISC FV Rivas, NH Tolia, JJ Song, JP Aragon, J Liu, GJ Hannon, L Joshua-Tor Nature structural & molecular biology 12 (4), 340-349, 2005 | 1007 | 2005 |
| The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes JJ Song, J Liu, NH Tolia, J Schneiderman, SK Smith, RA Martienssen, ... Nature Structural & Molecular Biology 10 (12), 1026-1032, 2003 | 837 | 2003 |
| Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi EBPJ Yigit, YPKM Bei, CCGTNH Chen, LMS Joshua-Tor, MJMCC Simard Cell 127 (4), 747-758, 2006 | 792 | 2006 |
| Slicer and the argonautes NH Tolia, L Joshua-Tor Nature chemical biology 3 (1), 36-43, 2007 | 682 | 2007 |
| Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum NH Tolia, EJ Enemark, BKL Sim, L Joshua-Tor Cell 122 (2), 183-193, 2005 | 384 | 2005 |
| Strategies for protein coexpression in Escherichia coli NH Tolia, L Joshua-Tor Nature methods 3 (1), 55-64, 2006 | 329 | 2006 |
| Argonaute slicing is required for heterochromatic silencing and spreading DV Irvine, M Zaratiegui, NH Tolia, DB Goto, DH Chitwood, MW Vaughn, ... Science 313 (5790), 1134-1137, 2006 | 263 | 2006 |
| Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion AS Nasamu, S Glushakova, I Russo, B Vaupel, A Oksman, AS Kim, ... Science 358 (6362), 518-522, 2017 | 186 | 2017 |
| Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC JD Batchelor, JA Zahm, NH Tolia Nature structural & molecular biology 18 (8), 908-914, 2011 | 172 | 2011 |
| Allosteric activation of ADAMTS13 by von Willebrand factor J Muia, J Zhu, G Gupta, SL Haberichter, KD Friedman, HB Feys, ... Proceedings of the National Academy of Sciences 111 (52), 18584-18589, 2014 | 161 | 2014 |
| Protein-based antigen presentation platforms for nanoparticle vaccines B Nguyen, NH Tolia npj Vaccines 6 (1), 70, 2021 | 155 | 2021 |
| Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance AJ Gasparrini, JL Markley, H Kumar, B Wang, L Fang, S Irum, CT Symister, ... Communications biology 3 (1), 241, 2020 | 155 | 2020 |
| Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC JD Batchelor, BM Malpede, NS Omattage, GT DeKoster, ... PLoS pathogens 10 (1), e1003869, 2014 | 126 | 2014 |
| Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes J Park, AJ Gasparrini, MR Reck, CT Symister, JL Elliott, JP Vogel, ... Nature chemical biology 13 (7), 730-736, 2017 | 123 | 2017 |
| Data publication with the structural biology data grid supports live analysis PA Meyer, S Socias, J Key, E Ransey, EC Tjon, A Buschiazzo, M Lei, ... Nature communications 7 (1), 10882, 2016 | 116 | 2016 |
| Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii MS Behnke, A Khan, EJ Lauron, JR Jimah, Q Wang, NH Tolia, LD Sibley PLoS genetics 11 (8), e1005434, 2015 | 111 | 2015 |
| Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein E Chen, ND Salinas, Y Huang, F Ntumngia, MD Plasencia, ML Gross, ... Proceedings of the National Academy of Sciences 113 (22), 6277-6282, 2016 | 101 | 2016 |
| A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites AM Guggisberg, J Park, RL Edwards, ML Kelly, DM Hodge, NH Tolia, ... Nature communications 5 (1), 4467, 2014 | 90 | 2014 |
| Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion M Koch, KE Wright, O Otto, M Herbig, ND Salinas, NH Tolia, TJ Satchwell, ... Proceedings of the National Academy of Sciences 114 (16), 4225-4230, 2017 | 89 | 2017 |
| Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175 E Chen, MM Paing, N Salinas, BKL Sim, NH Tolia PLoS pathogens 9 (5), e1003390, 2013 | 78 | 2013 |
Edwin ChenHarvard UniversityVerified email at partners.org
