| VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1 MI Capurro, LK Greenfield, A Prashar, S Xia, M Abdullah, H Wong, ... Nature microbiology 4 (8), 1411-1423, 2019 | 96 | 2019 |
| Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells AP Wong, S Chin, S Xia, J Garner, CE Bear, J Rossant nature protocols 10 (3), 363-381, 2015 | 79 | 2015 |
| Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia S Ahmadi, Z Bozoky, M Di Paola, S Xia, C Li, AP Wong, L Wellhauser, ... NPJ genomic medicine 2 (1), 12, 2017 | 69 | 2017 |
| ORKAMBI-mediated rescue of mucociliary clearance in cystic fibrosis primary respiratory cultures is enhanced by arginine uptake, arginase inhibition, and promotion of nitric … YS Wu, J Jiang, S Ahmadi, A Lew, O Laselva, S Xia, C Bartlett, W Ip, ... Molecular Pharmacology 96 (4), 515-525, 2019 | 46 | 2019 |
| SLC6A14, an amino acid transporter, modifies the primary CF defect in fluid secretion S Ahmadi, S Xia, YS Wu, M Di Paola, R Kissoon, C Luk, F Lin, K Du, ... Elife 7, e37963, 2018 | 37 | 2018 |
| Generation of functional ciliated cholangiocytes from human pluripotent stem cells M Ogawa, JX Jiang, S Xia, D Yang, A Ding, O Laselva, M Hernandez, ... Nature communications 12 (1), 6504, 2021 | 25 | 2021 |
| A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients JX Jiang, L Wellhauser, O Laselva, I Utkina, Z Bozoky, T Gunawardena, ... Stem cell reports 16 (11), 2825-2837, 2021 | 24 | 2021 |
| Augmentation of cystic fibrosis transmembrane conductance regulator function in human bronchial epithelial cells via SLC6A14-dependent amino acid uptake. Implications for … S Ahmadi, YS Wu, M Li, W Ip, A Lloyd-Kuzik, M Di Paola, K Du, S Xia, ... American journal of respiratory cell and molecular biology 61 (6), 755-764, 2019 | 15 | 2019 |
| An organoid model to assay the role of CFTR in the human epididymis epithelium SH Leir, S Yin, JL Kerschner, S Xia, S Ahmadi, C Bear, A Harris Cell and tissue research 381, 327-336, 2020 | 14 | 2020 |
| Conversion of human and mouse fibroblasts into lung-like epithelial cells AP Wong, S Shojaie, Q Liang, S Xia, M Di Paola, S Ahmadi, C Bilodeau, ... Scientific reports 9 (1), 9027, 2019 | 12 | 2019 |
| High-throughput functional analysis of CFTR and other apically localized proteins in iPSC-derived human intestinal organoids S Xia, Z Bozóky, M Di Paola, O Laselva, S Ahmadi, JX Jiang, AL Pitstick, ... Cells 10 (12), 3419, 2021 | 8 | 2021 |
| Stage‐Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function SY Ngan, HT Quach, O Laselva, EN Huang, M Mangos, S Xia, CE Bear, ... Current Protocols 2 (1), e341, 2022 | 7 | 2022 |
| Perspectives on the translation of in-vitro studies to precision medicine in Cystic Fibrosis MP Dumas, S Xia, CE Bear, F Ratjen EBioMedicine 73, 2021 | 7 | 2021 |
| Modeling lung cell development using human pluripotent stem cells SY Ngan, H Quach, J Dierolf, O Laselva, JA Lee, E Huang, M Mangos, ... bioRxiv, 2021.07. 16.452691, 2021 | 6 | 2021 |
| High-throughput functional analysis of CFTR and other apically localized channels in iPSC derived intestinal organoids S Xia, Z Bozóky, O Laselva, M Di Paola, S Ahmadi, JX Jiang, A Pitstick, ... bioRxiv, 2021.07. 07.451180, 2021 | 5 | 2021 |
| A new platform for high-throughput therapy testing on iPSC-derived, immature airway from Cystic Fibrosis Patients JX Jiang, L Wellhauser, O Laselva, I Utkina, Z Bozoky, T Gunawardena, ... bioRxiv, 2021.07. 05.451013, 2021 | 3 | 2021 |
| SLC6A14 Modifies Fluid Secretory Capacity of Cystic Fibrosis Affected Epithelium by Enhancing CFTR Channel Function S Ahmadi, C Luk, S Xia, M Di Paola, T Chung, J Rommens, C Bear Biophysical Journal 108 (2), 19a-20a, 2015 | 2 | 2015 |
| SLC6A14 Enhances CFTR Channel Activity in the Cystic Fibrosis Affected Lung Epithelium S Ahmadi, S Xia, M Di Paola, W Ip, J Rommens, T Gonska, CE Bear Biophysical Journal 110 (3), 452a, 2016 | 1 | 2016 |
| Benchmarking organ-specific responses to therapies in tissues differentiated from Cystic Fibrosis patient derived iPSCs A Daoud, S Xia, O Laselva, JX Jiang, C Bear bioRxiv, 2024.03. 13.584768, 2024 | | 2024 |
| A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines S Xia, M Di Paola, NL Jones, CE Bear JoVE (Journal of Visualized Experiments), e63528, 2022 | | 2022 |
