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D Posthuma
D Posthuma
VU University & VU University Medical Centre
Email confirmado em vu.nl - Página inicial
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Biological insights from 108 schizophrenia-associated genetic loci
C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ...
Nature 511 (7510), 421-427, 2014
73312014
Functional mapping and annotation of genetic associations with FUMA
K Watanabe, E Taskesen, A Van Bochoven, D Posthuma
Nature communications 8 (1), 1826, 2017
26762017
MAGMA: generalized gene-set analysis of GWAS data
CA de Leeuw, JM Mooij, T Heskes, D Posthuma
PLoS computational biology 11 (4), e1004219, 2015
25282015
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ...
Nature genetics 42 (2), 105-116, 2010
24762010
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ...
Nature genetics 42 (2), 105-116, 2010
24762010
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
24602018
Meta-analysis of the heritability of human traits based on fifty years of twin studies
TJC Polderman, B Benyamin, CA De Leeuw, PF Sullivan, ...
Nature genetics 47 (7), 702-709, 2015
23012015
Genome-wide association study identifies five new schizophrenia loci
Nature genetics 43 (10), 969-976, 2011
19862011
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
IE Jansen, JE Savage, K Watanabe, J Bryois, DM Williams, S Steinberg, ...
Nature genetics 51 (3), 404-413, 2019
18232019
Genome-wide association analysis identifies 13 new risk loci for schizophrenia
S Ripke, C O'dushlaine, K Chambert, JL Moran, AK Kähler, S Akterin, ...
Nature genetics 45 (10), 1150-1159, 2013
17192013
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
M Liu, Y Jiang, R Wedow, Y Li, DM Brazel, F Chen, G Datta, ...
Nature genetics 51 (2), 237-244, 2019
14332019
Genome-wide association study identifies 74 loci associated with educational attainment
A Okbay, JP Beauchamp, MA Fontana, JJ Lee, TH Pers, CA Rietveld, ...
Nature 533 (7604), 539-542, 2016
13652016
Genome-wide association study identifies 30 loci associated with bipolar disorder
EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ...
Nature genetics 51 (5), 793-803, 2019
13512019
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ...
Science 360 (6395), eaap8757, 2018
13472018
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
12932015
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Nature genetics 42 (5), 441-447, 2010
11002010
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
JE Savage, PR Jansen, S Stringer, K Watanabe, J Bryois, CA De Leeuw, ...
Nature genetics 50 (7), 912-919, 2018
10522018
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ...
Nature 604 (7906), 502-508, 2022
10502022
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ...
Cell 179 (7), 1469-1482. e11, 2019
10032019
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
CA Rietveld, SE Medland, J Derringer, J Yang, T Esko, NW Martin, ...
science 340 (6139), 1467-1471, 2013
9802013
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