Use of pharmaco‐metabonomics for early prediction of acetaminophen‐induced hepatotoxicity in humans JH Winnike, Z Li, FA Wright, JM Macdonald, TM O'connell, PB Watkins Clinical Pharmacology & Therapeutics 88 (1), 45-51, 2010 | 179 | 2010 |
Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation RD Fannin, M Russo, TM O'connell, K Gerrish, JH Winnike, J Macdonald, ... Hepatology 51 (1), 227-236, 2010 | 112 | 2010 |
Effects of a prolonged standardized diet on normalizing the human metabolome JH Winnike, MG Busby, PB Watkins, TM O’Connell The American journal of clinical nutrition 90 (6), 1496-1501, 2009 | 87 | 2009 |
Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease BU Bradford, TM O'connell, J Han, O Kosyk, S Shymonyak, PK Ross, ... Toxicology and applied pharmacology 232 (2), 236-243, 2008 | 81 | 2008 |
Comparison of GC-MS and GC× GC-MS in the analysis of human serum samples for biomarker discovery JH Winnike, X Wei, KJ Knagge, SD Colman, SG Gregory, X Zhang Journal of proteome research 14 (4), 1810-1817, 2015 | 80 | 2015 |
Metabolomic analysis of cancer cachexia reveals distinct lipid and glucose alterations TM O’Connell, F Ardeshirpour, SA Asher, JH Winnike, X Yin, J George, ... Metabolomics 4 (3), 216, 2008 | 56 | 2008 |
Metabolome-based signature of disease pathology in MS SL Andersen, FBS Briggs, JH Winnike, Y Natanzon, S Maichle, ... Multiple sclerosis and related disorders, 2019 | 47 | 2019 |
Metabolomics analysis of hormone-responsive and triple-negative breast cancer cell responses to paclitaxel identify key metabolic differences DA Stewart, JH Winnike, SL McRitchie, RF Clark, WW Pathmasiri, ... Journal of proteome research 15 (9), 3225-3240, 2016 | 47 | 2016 |
High-throughput nuclear magnetic resonance metabolomic footprinting for tissue engineering C Seagle, MA Christie, JH Winnike, RE McClelland, JW Ludlow, ... Tissue Engineering Part C: Methods 14 (2), 107-118, 2008 | 27 | 2008 |
Cancer cachexia’s metabolic signature in a murine model confirms a distinct entity H Der-Torossian, SA Asher, JH Winnike, A Wysong, X Yin, MS Willis, ... Metabolomics 9 (3), 730-739, 2013 | 26 | 2013 |
Stable Isotope-Resolved Metabolomic Differences between Hormone-Responsive and Triple-Negative Breast Cancer Cell Lines JH Winnike, DA Stewart, WW Pathmasiri, SL McRitchie, SJ Sumner International journal of breast cancer 2018, 2018 | 25 | 2018 |
Stable isotope resolved metabolomics of primary human hepatocytes reveals a stressed phenotype JH Winnike, P Pediaditakis, JE Wolak, RE McClelland, PB Watkins, ... Metabolomics 8 (1), 34-49, 2012 | 17 | 2012 |
Noninvasive fluxomics in mammals by nuclear magnetic resonance spectroscopy J Wolak, K Rahimi-Keshari, RE Jeffries, MP Joy, A Todd, P Pediatitakis, ... The handbook of metabolomics, 321-392, 2012 | 9 | 2012 |
Fluxomics by NMR spectroscopy from cells to organisms focusing on liver AP Tikunov, JH Winnike, K Tech, RE Jeffries, CT Semelka, J Martin, ... Current Metabolomics 1 (2), 128-159, 2013 | 8 | 2013 |
Triple negative breast cancer: Metabolomics and flux analysis to identify targets for drug development DA Stewart, J Winnike, S McRitchie, W Pathmasiri, S Sumner Cancer Research 75 (15 Supplement), 1836-1836, 2015 | 2 | 2015 |
The metabolomics of acetaminophen toxicity observed in human biofluids and cultured primary human hepatocytes JH Winnike The University of North Carolina at Chapel Hill, 2010 | 1 | 2010 |
Metabolomic analysis of urine and liver after chronic alcohol treatment in C57BL/6J mice BU Bradford, J Han, O Kosyk, S Shymonyak, J Winnike, H Kono, ... HEPATOLOGY 46 (4), 811A-811A, 2007 | 1 | 2007 |
Relationship in Broccoli Between Genetic Mapping and Small Molecule Profiling Using NMR Spectroscopy K Knagge, G Yousef, J Winnike, K Blankenship, A Thomas, A Brown The FASEB Journal 31 (1_supplement), 766.11-766.11, 2017 | | 2017 |
Integrated metabolomic and transcriptomic profiles of males with multiple sclerosis SA Cote, SG Gregory, J Winnike, K Knagge, O Ilkayeva, T O'Connell, ... MULTIPLE SCLEROSIS JOURNAL 22, 9-10, 2016 | | 2016 |
Metabolomic Effects of Acetaminophen on Human Biofluids JH Winnike University of North Carolina at Chapel Hill, 2005 | | 2005 |