| Phage antibodies: filamentous phage displaying antibody variable domains J McCafferty, AD Griffiths, G Winter, DJ Chiswell nature 348 (6301), 552-554, 1990 | 3993 | 1990 |
| Reshaping human antibodies for therapy L Riechmann, M Clark, H Waldmann, G Winter Nature 332 (6162), 323-327, 1988 | 3578 | 1988 |
| Replacing the complementarity-determining regions in a human antibody with those from a mouse PT Jones, PH Dear, J Foote, MS Neuberger, G Winter Nature 321 (6069), 522-525, 1986 | 3045 | 1986 |
| By-passing immunization: human antibodies from V-gene libraries displayed on phage JD Marks, HR Hoogenboom, TP Bonnert, J McCafferty, AD Griffiths, ... Journal of molecular biology 222 (3), 581-597, 1991 | 2852 | 1991 |
| Making antibodies by phage display technology G Winter, AD Griffiths, RE Hawkins, HR Hoogenboom Annual review of immunology 12 (1), 433-455, 1994 | 2568 | 1994 |
| Making antibody fragments using phage display libraries T Clackson, HR Hoogenboom, AD Griffiths, G Winter Nature 352 (6336), 624-628, 1991 | 2477 | 1991 |
| " Diabodies": small bivalent and bispecific antibody fragments. P Holliger, T Prospero, G Winter Proceedings of the National Academy of Sciences 90 (14), 6444-6448, 1993 | 2232 | 1993 |
| Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli ES Ward, D Güssow, AD Griffiths, PT Jones, G Winter Nature 341 (6242), 544-546, 1989 | 2202 | 1989 |
| Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains HR Hoogenboom, AD Griffiths, KS Johnson, DJ Chiswell, P Hudson, ... Nucleic acids research 19 (15), 4133-4137, 1991 | 1712 | 1991 |
| Man-made antibodies G Winter, C Milstein Nature 349 (6307), 293-299, 1991 | 1702 | 1991 |
| Hydrogen bonding and biological specificity analysed by protein engineering AR Fersht, JP Shi, J Knill-Jones, DM Lowe, AJ Wilkinson, DM Blow, ... Nature 314 (6008), 235-238, 1985 | 1339 | 1985 |
| Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. R Orlandi, DH Güssow, PT Jones, G Winter Proceedings of the National Academy of Sciences 86 (10), 3833-3837, 1989 | 1313 | 1989 |
| By-passing immunisation: human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro HR Hoogenboom, G Winter Journal of molecular biology 227 (2), 381-388, 1992 | 1177* | 1992 |
| Reshaping human antibodies: grafting an antilysozyme activity M Verhoeyen, C Milstein, G Winter Science 239 (4847), 1534-1536, 1988 | 1148 | 1988 |
| By–passing immunization: building high affinity human antibodies by chain shuffling JD Marks, AD Griffiths, M Malmqvist, TP Clackson, JM Bye, G Winter Bio/technology 10 (7), 779-783, 1992 | 1064 | 1992 |
| Selection of phage antibodies by binding affinity: mimicking affinity maturation RE Hawkins, SJ Russell, G Winter Journal of molecular biology 226 (3), 889-896, 1992 | 1032 | 1992 |
| The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops IM Tomlinson, G Walter, JD Marks, MB Llewelyn, G Winter Journal of molecular biology 227 (3), 776-798, 1992 | 981 | 1992 |
| The binding site for C1q on IgG AR Duncan, G Winter Nature 332 (6166), 738-740, 1988 | 928 | 1988 |
| Antibody fragments from a ‘single pot’phage display library as immunochemical reagents. A Nissim, HR Hoogenboom, IM Tomlinson, G Flynn, C Midgley, D Lane, ... The EMBO journal 13 (3), 692-698, 1994 | 924 | 1994 |
| Antibody framework residues affecting the conformation of the hypervariable loops J Foote, G Winter Journal of molecular biology 224 (2), 487-499, 1992 | 905 | 1992 |
