Juan José Galano Frutos
Juan José Galano Frutos
Ph. D. in Biochemistry and Molecular Biology, University of Zaragoza
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Antimicrobial susceptibility and resistance patterns among Helicobacter pylori strains from The Gambia, West Africa
O Secka, DE Berg, M Antonio, T Corrah, M Tapgun, R Walton, V Thomas, ...
Antimicrobial agents and chemotherapy 57 (3), 1231-1237, 2013
Improved Flavodoxin Inhibitors with Potential Therapeutic Effects against Helicobacter pylori Infection
JJ Galano, M Alías, R Pérez, A Velázquez-Campoy, PS Hoffman, ...
Journal of Medicinal Chemistry 56 (15), 6248-6258, 2013
Design, Synthesis, and Efficacy Testing of Nitroethylene- and 7-Nitrobenzoxadiazol-Based Flavodoxin Inhibitors against Helicobacter pylori Drug-Resistant Clinical Strains …
S Salillas, M Alías, V Michel, A Mahía, A Lucía, L Rodrigues, J Bueno, ...
Journal of Medicinal Chemistry 62 (13), 6102-6115, 2019
Molecular dynamics simulations for genetic interpretation in protein coding regions: where we are, where to go and when
JJ Galano-Frutos, H García-Cebollada, J Sancho
Briefings in Bioinformatics 22 (1), 3-19, 2021
Accurate calculation of Barnase and SNase folding energetics using short molecular dynamics simulations and an atomistic model of the unfolded ensemble: Evaluation of force …
JJ Galano-Frutos, J Sancho
Journal of Chemical Information and Modeling 59 (10), 4350-4360, 2019
Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position
JA Gálvez, R Clavería-Gimeno, JJ Galano-Frutos, J Sancho, ...
European Journal of Medicinal Chemistry 171, 401-419, 2019
Protein haploinsufficiency drivers identify MYBPC3 variants that cause hypertrophic cardiomyopathy
C Suay-Corredera, MR Pricolo, E Herrero-Galán, D Velázquez-Carreras, ...
Journal of Biological Chemistry, 2021
Insights into immune evasion of human metapneumovirus: novel 180- and 111-nucleotide duplications within viral G gene throughout 2014-2017 seasons in Barcelona, Spain.
M Piñana, J Vila, C Maldonado, JJ Galano-Frutos, M Valls, J Sancho, ...
Journal of Clinical Virology, 2020
Protein haploinsufficiency drivers identify MYBPC3 mutations that cause hypertrophic cardiomyopathy
C Suay-Corredera, MR Pricolo, E Herrero-Galan, D Velazquez-Carreras, ...
MedRxiv, 2020
Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability
A Mahía, S Peña-Díaz, S Navarro, JJ Galano-Frutos, I Pallarés, J Pujols, ...
Bioorganic Chemistry 117, 105472, 2021
New variant (Val597Ile) in transmembrane region of the TSH receptor with human chorionic gonadotropin hypersensitivity in familial gestational hyperthyroidism
P Caron, S Broussaud, JJ Galano‐Frutos, J Sancho, F Savagner
Clinical Endocrinology 93 (3), 339-345, 2020
A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of Aβ1–42, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus …
A Mahía, M Conde-Giménez, S Salillas, I Pallarés, JJ Galano-Frutos, ...
Analytical and bioanalytical chemistry 411 (1), 251-265, 2019
Direct examination of the relevance for folding, binding and electron transfer of a conserved protein folding intermediate
E Lamazares, S Vega, P Ferreira, M Medina, JJ Galano-Frutos, ...
Physical Chemistry Chemical Physics 19 (29), 19021-19031, 2017
The mechanism of water/ion exchange at a protein surface: a weakly bound chloride in Helicobacter pylori apoflavodoxin
JJ Galano-Frutos, MC Morón, J Sancho
Physical Chemistry Chemical Physics 17 (43), 28635-28646, 2015
Selective Targeting of Human and Animal Pathogens of the Helicobacter Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies
S Salillas, JJ Galano-Frutos, A Mahía, R Maity, M Conde-Giménez, ...
International Journal of Molecular Sciences 22 (18), 10137, 2021
QSAR Models for Prediction of Binding and Inhibitory Properties of [(E)-2- R-vinyl]benzene Derivatives with Therapeutic Effects against Helicobacter pylori.
JJ Galano, J Sancho
Medicinal Chemistry 4 (1), 306-312, 2013
A look at the face of the molten globule: Structural model of the Helicobacter pylori apoflavodoxin ensemble at acidic pH
JJ Galano‐Frutos, R Torreblanca, H García‐Cebollada, J Sancho
Protein Science 31 (11), e4445, 2022
Accurate and efficient constrained molecular dynamics of polymers through Newton's method and special purpose code
L López-Villellas, CC Kjelgaard Mikkelsen, JJ Galano-Frutos, ...
bioRxiv, 2022
Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine Hydroxylase
M Conde-Giménez, JJ Galano-Frutos, M Galiana-Cameo, A Mahía, ...
International Journal of Molecular Sciences 23 (9), 4502, 2022
PirePred: An Accurate Online Consensus Tool to Interpret Newborn Screening–Related Genetic Variants in Structural Context
JJ Galano-Frutos, H García-Cebollada, A López, M Rosell, X de la Cruz, ...
The Journal of Molecular Diagnostics 24 (4), 406-425, 2022
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