| Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action HJ Kim, M Rowe, M Ren, JS Hong, PS Chen, DM Chuang Journal of Pharmacology and Experimental Therapeutics 321 (3), 892-901, 2007 | 630 | 2007 |
| Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes PS Chen, GS Peng, G Li, S Yang, X Wu, CC Wang, B Wilson, RB Lu, ... Molecular psychiatry 11 (12), 1116-1125, 2006 | 412 | 2006 |
| Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons X Wu, PS Chen, S Dallas, B Wilson, ML Block, CC Wang, H Kinyamu, ... International Journal of Neuropsychopharmacology 11 (8), 1123-1134, 2008 | 336 | 2008 |
| Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity PS Chen, CC Wang, CD Bortner, GS Peng, X Wu, H Pang, RB Lu, ... Neuroscience 149 (1), 203-212, 2007 | 295 | 2007 |
| Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia GS Peng, G Li, NS Tzeng, PS Chen, DM Chuang, YD Hsu, S Yang, ... Molecular Brain Research 134 (1), 162-169, 2005 | 211 | 2005 |
| Glycogen synthase kinase‐3 negatively regulates anti‐inflammatory interleukin‐10 for lipopolysaccharide‐induced iNOS/NO biosynthesis and RANTES production in microglial cells WC Huang, YS Lin, CY Wang, CC Tsai, HC Tseng, CL Chen, PJ Lu, ... Immunology 128 (1pt2), e275-e286, 2009 | 155 | 2009 |
| Treatment response and cognitive impairment in major depression: association with C-reactive protein HH Chang, IH Lee, PW Gean, SY Lee, MH Chi, YK Yang, RB Lu, PS Chen Brain, behavior, and immunity 26 (1), 90-95, 2012 | 130 | 2012 |
| Methods related to the treatment of neurodegenerative and inflammatory conditions JS Hong, L Qin, G Li, M Block, W Zhang, PS Chen, GS Peng US Patent 8,796,302, 2014 | 125 | 2014 |
| Correlation between body mass index and striatal dopamine transporter availability in healthy volunteers—a SPECT study PS Chen, YK Yang, TL Yeh, IH Lee, WJ Yao, NT Chiu, RB Lu Neuroimage 40 (1), 275-279, 2008 | 121 | 2008 |
| Clozapine protects dopaminergic neurons from inflammation-induced damage by inhibiting microglial overactivation X Hu, H Zhou, D Zhang, S Yang, L Qian, HM Wu, PS Chen, B Wilson, ... Journal of Neuroimmune Pharmacology 7, 187-201, 2012 | 119 | 2012 |
| The amygdala excitatory/inhibitory balance in a valproate-induced rat autism model HC Lin, PW Gean, CC Wang, YH Chan, PS Chen PLos one 8 (1), e55248, 2013 | 106 | 2013 |
| Arecoline, a major alkaloid of the areca nut, causes neurotoxicity through enhancement of oxidative stress and suppression of the antioxidant protective system YT Shih, PS Chen, CH Wu, YT Tseng, YC Wu, YC Lo Free Radical Biology and Medicine 49 (10), 1471-1479, 2010 | 101 | 2010 |
| Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4–6 are neuroprotective through inhibition of NADPH oxidase: potent regulators of microglia-mediated … S Yang, J Yang, Z Yang, P Chen, A Fraser, W Zhang, H Pang, X Gao, ... Journal of Pharmacology and Experimental Therapeutics 319 (2), 595-603, 2006 | 88 | 2006 |
| Different dimensions of social support for the caregivers of patients with schizophrenia: Main effect and stress‐buffering models TC Lee, YK Yang, PS Chen, NC Hung, SH Lin, FL Chang, SH Cheng Psychiatry and Clinical Neurosciences 60 (5), 546-550, 2006 | 87 | 2006 |
| High prevalence of metabolic disturbances in patients with bipolar disorder in Taiwan HH Chang, CH Chou, PS Chen, PW Gean, HC Huang, CY Lin, YK Yang, ... Journal of affective disorders 117 (1-2), 124-129, 2009 | 85 | 2009 |
| Decreased dopamine transporter availability in male smokers—a dual isotope SPECT study YK Yang, WJ Yao, TL Yeh, IH Lee, PS Chen, RB Lu, NT Chiu Progress in Neuro-Psychopharmacology and Biological Psychiatry 32 (1), 274-279, 2008 | 85 | 2008 |
| Associated alterations of striatal dopamine D2/D3 receptor and transporter binding in drug-naive patients with schizophrenia: a dual-isotope SPECT study YK Yang, L Yu, TL Yeh, NT Chiu, PS Chen, IH Lee American Journal of Psychiatry 161 (8), 1496-1498, 2004 | 82 | 2004 |
| Interaction of serotonin-related genes affects short-term antidepressant response in major depressive disorder E Lin, PS Chen, HH Chang, PW Gean, HC Tsai, YK Yang, RB Lu Progress in Neuro-Psychopharmacology and Biological Psychiatry 33 (7), 1167-1172, 2009 | 79 | 2009 |
| Glutamate preconditioning prevents neuronal death induced by combined oxygen–glucose deprivation in cultured cortical neurons CH Lin, PS Chen, PW Gean European journal of pharmacology 589 (1-3), 85-93, 2008 | 75 | 2008 |
| Greater availability of dopamine transporters in patients with major depression—a dual-isotope SPECT study YK Yang, TL Yeh, WJ Yao, IH Lee, PS Chen, NT Chiu, RB Lu Psychiatry Research: Neuroimaging 162 (3), 230-235, 2008 | 75 | 2008 |
