Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL) M Duvic, R Talpur, X Ni, C Zhang, P Hazarika, C Kelly, JH Chiao, JF Reilly, ... Blood 109 (1), 31-39, 2007 | 1307 | 2007 |
Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes G Garcia-Manero, H Yang, C Bueso-Ramos, A Ferrajoli, J Cortes, ... Blood, The Journal of the American Society of Hematology 111 (3), 1060-1066, 2008 | 553 | 2008 |
Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study E Galanis, KA Jaeckle, MJ Maurer, JM Reid, MM Ames, JS Hardwick, ... Journal of clinical oncology 27 (12), 2052-2058, 2009 | 405 | 2009 |
Importin β–mediated nuclear import of fibroblast growth factor receptor: role in cell proliferation JF Reilly, PA Maher The Journal of cell biology 152 (6), 1307-1312, 2001 | 280 | 2001 |
Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis JM Redwine, B Kosofsky, RE Jacobs, D Games, JF Reilly, JH Morrison, ... Proceedings of the National Academy of Sciences 100 (3), 1381-1386, 2003 | 233 | 2003 |
Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis E Benedettini, LM Sholl, M Peyton, J Reilly, C Ware, L Davis, N Vena, ... The American journal of pathology 177 (1), 415-423, 2010 | 208 | 2010 |
Adult mouse brain gene expression patterns bear an embryologic imprint MA Zapala, I Hovatta, JA Ellison, L Wodicka, JA Del Rio, R Tennant, ... Proceedings of the National Academy of Sciences 102 (29), 10357-10362, 2005 | 207 | 2005 |
Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma VR Fantin, A Loboda, CP Paweletz, RC Hendrickson, JW Pierce, JA Roth, ... Cancer research 68 (10), 3785-3794, 2008 | 206 | 2008 |
Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model JF Reilly, D Games, RE Rydel, S Freedman, D Schenk, WG Young, ... Proceedings of the National Academy of Sciences 100 (8), 4837-4842, 2003 | 206 | 2003 |
Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks D Palmieri, PR Lockman, FC Thomas, E Hua, J Herring, E Hargrave, ... Clinical Cancer Research 15 (19), 6148-6157, 2009 | 176 | 2009 |
Regulation of astrocyte GFAP expression by TGF‐β1 and FGF‐2 JF Reilly, PA Maher, VG Kumari Glia 22 (2), 202-210, 1998 | 139 | 1998 |
Downregulation of Notch pathway by a γ-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model CL Efferson, CT Winkelmann, C Ware, T Sullivan, S Giampaoli, ... Cancer research 70 (6), 2476-2484, 2010 | 113 | 2010 |
Alterations in fibroblast growth factor receptor expression following brain injury JF Reilly, VG Kumari Experimental neurology 140 (2), 139-150, 1996 | 96 | 1996 |
MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor BS Pan, GKY Chan, M Chenard, A Chi, LJ Davis, SV Deshmukh, JB Gibbs, ... Cancer research 70 (4), 1524-1533, 2010 | 91 | 2010 |
Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer W Zhang, J Zhu, CL Efferson, C Ware, J Tammam, M Angagaw, J Laskey, ... Cancer research 69 (18), 7466-7472, 2009 | 91 | 2009 |
Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia J Tammam, C Ware, C Efferson, J O'neil, S Rao, X Qu, J Gorenstein, ... British journal of pharmacology 158 (5), 1183-1195, 2009 | 88 | 2009 |
Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14: characterization of a new receptor binding partner JF Reilly, G Mickey, PA Maher Journal of Biological Chemistry 275 (11), 7771-7778, 2000 | 80 | 2000 |
Phase I study of accelerated conformal radiotherapy for stage I non–small-cell lung cancer in patients with pulmonary dysfunction: CALGB 39904 JA Bogart, L Hodgson, SL Seagren, AW Blackstock, X Wang, R Lenox, ... Journal of clinical oncology 28 (2), 202-206, 2010 | 74 | 2010 |
Ligand dependent and independent internalization and nuclear translocation of fibroblast growth factor (FGF) receptor 1 JF Reilly, E Mizukoshi, PA Maher DNA and cell biology 23 (9), 538-548, 2004 | 69 | 2004 |
Discovery of a 5H-Benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer JD Katz, JP Jewell, DJ Guerin, J Lim, CJ Dinsmore, SV Deshmukh, ... Journal of medicinal chemistry 54 (12), 4092-4108, 2011 | 60 | 2011 |