Multistep protein unfolding during nanopore translocation D Rodriguez-Larrea, H Bayley Nature nanotechnology 8 (4), 288-295, 2013 | 323 | 2013 |
The emerging landscape of single-molecule protein sequencing technologies JA Alfaro, P Bohländer, M Dai, M Filius, CJ Howard, XF Van Kooten, ... Nature methods 18 (6), 604-617, 2021 | 277 | 2021 |
Single-molecule site-specific detection of protein phosphorylation with a nanopore CB Rosen, D Rodriguez-Larrea, H Bayley Nature biotechnology 32 (2), 179-181, 2014 | 268 | 2014 |
Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF NG Housden, JTS Hopper, N Lukoyanova, D Rodriguez-Larrea, ... Science 340 (6140), 1570-1574, 2013 | 138 | 2013 |
Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy R Perez-Jimenez, J Li, P Kosuri, I Sanchez-Romero, AP Wiita, ... Nature structural & molecular biology 16 (8), 890-896, 2009 | 119 | 2009 |
Role of solvation barriers in protein kinetic stability D Rodriguez-Larrea, S Minning, TV Borchert, JM Sanchez-Ruiz Journal of molecular biology 360 (3), 715-724, 2006 | 104 | 2006 |
Structural basis of human triosephosphate isomerase deficiency: mutation E104D is related to alterations of a conserved water network at the dimer interface C Rodriguez-Almazan, R Arreola, D Rodriguez-Larrea, B Aguirre-López, ... Journal of Biological Chemistry 283 (34), 23254-23263, 2008 | 98 | 2008 |
Natural selection for kinetic stability is a likely origin of correlations between mutational effects on protein energetics and frequencies of amino acid occurrences in … R Godoy-Ruiz, F Ariza, D Rodriguez-Larrea, R Perez-Jimenez, ... Journal of molecular biology 362 (5), 966-978, 2006 | 84 | 2006 |
Protein co-translocational unfolding depends on the direction of pulling D Rodriguez-Larrea, H Bayley Nature communications 5 (1), 4841, 2014 | 68 | 2014 |
Between-species variation in the kinetic stability of TIM proteins linked to solvation-barrier free energies M Costas, D Rodríguez-Larrea, L De Maria, TV Borchert, A Gómez-Puyou, ... Journal of molecular biology 385 (3), 924-937, 2009 | 58 | 2009 |
Three-way interaction between 14-3-3 proteins, the N-terminal region of tyrosine hydroxylase, and negatively charged membranes Ø Halskau, M Ying, A Baumann, R Kleppe, D Rodriguez-Larrea, B Almås, ... Journal of Biological Chemistry 284 (47), 32758-32769, 2009 | 56 | 2009 |
Engineering proteins with tunable thermodynamic and kinetic stabilities AL Pey, D Rodriguez‐Larrea, S Bomke, S Dammers, R Godoy‐Ruiz, ... Proteins: Structure, Function, and Bioinformatics 71 (1), 165-174, 2008 | 56 | 2008 |
Label-free, multiplexed, single-molecule analysis of protein–DNA complexes with nanopores G Celaya, J Perales-Calvo, A Muga, F Moro, D Rodriguez-Larrea ACS nano 11 (6), 5815-5825, 2017 | 39 | 2017 |
Modulation of buried ionizable groups in proteins with engineered surface charge AL Pey, D Rodriguez-Larrea, JA Gavira, B Garcia-Moreno, ... Journal of the American Chemical Society 132 (4), 1218-1219, 2010 | 35 | 2010 |
Force-clamp spectroscopy detects residue co-evolution in enzyme catalysis R Perez-Jimenez, AP Wiita, D Rodriguez-Larrea, P Kosuri, JA Gavira, ... Journal of Biological Chemistry 283 (40), 27121-27129, 2008 | 34 | 2008 |
Role of conservative mutations in protein multi-property adaptation D Rodriguez-Larrea, R Perez-Jimenez, I Sanchez-Romero, ... Biochemical Journal 429 (2), 243-249, 2010 | 27 | 2010 |
Proteolytic scanning calorimetry: a novel methodology that probes the fundamental features of protein kinetic stability G Tur-Arlandis, D Rodriguez-Larrea, B Ibarra-Molero, JM Sanchez-Ruiz Biophysical Journal 98 (6), L12-L14, 2010 | 27 | 2010 |
Using multi-objective computational design to extend protein promiscuity M Suarez, P Tortosa, MM Garcia-Mira, D Rodríguez-Larrea, ... Biophysical chemistry 147 (1-2), 13-19, 2010 | 25 | 2010 |
Energetic and structural consequences of desolvation/solvation barriers to protein folding/unfolding assessed from experimental unfolding rates D Rodriguez-Larrea, B Ibarra-Molero, JM Sanchez-Ruiz Biophysical journal 91 (5), L48-L50, 2006 | 24 | 2006 |
Protein–protein interactions at an enzyme–substrate interface: Characterization of transient reaction intermediates throughout a full catalytic cycle of Escherichia coli … A Negri, D Rodríguez‐Larrea, E Marco, A Jiménez‐Ruiz, ... Proteins: Structure, Function, and Bioinformatics 78 (1), 36-51, 2010 | 22 | 2010 |