R. Bryn Fenwick
R. Bryn Fenwick
Ambry Genetics
Verified email at ambrygen.com - Homepage
TitleCited byYear
Weak long-range correlated motions in a surface patch of ubiquitin involved in molecular recognition
RB Fenwick, S Esteban-Martín, B Richter, D Lee, KFA Walter, ...
Journal of the American Chemical Society 133 (27), 10336-10339, 2011
1412011
Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR
RB Fenwick, H van den Bedem, JS Fraser, PE Wright
Proceedings of the National Academy of Sciences 111 (4), E445-E454, 2014
962014
Understanding biomolecular motion, recognition, and allostery by use of conformational ensembles
RB Fenwick, S Esteban-Martín, X Salvatella
European Biophysics Journal 40 (12), 1339-1355, 2011
872011
Kinetics of conformational sampling in ubiquitin
D Ban, M Funk, R Gulich, D Egger, TM Sabo, KFA Walter, RB Fenwick, ...
Angewandte Chemie International Edition 50 (48), 11437-11440, 2011
652011
RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation
M Morales, EJ Arenas, J Urosevic, M Guiu, E Fernández, E Planet, ...
EMBO molecular medicine 6 (7), 865-881, 2014
552014
Refinement of ensembles describing unstructured proteins using NMR residual dipolar couplings
S Esteban-Martín, RB Fenwick, X Salvatella
Journal of the American Chemical Society 132 (13), 4626-4632, 2010
552010
Correlated motions are a fundamental property of β-sheets
RB Fenwick, L Orellana, S Esteban-Martín, M Orozco, X Salvatella
Nature communications 5, 4070, 2014
522014
EPI-001, a compound active against castration-resistant prostate cancer, targets transactivation unit 5 of the androgen receptor
E De Mol, RB Fenwick, CTW Phang, V Buzón, E Szulc, A De La Fuente, ...
ACS chemical biology 11 (9), 2499-2505, 2016
382016
Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding
RB Fenwick, S Prasannan, LJ Campbell, D Nietlispach, KA Evetts, ...
Biochemistry 48 (10), 2192-2206, 2009
382009
The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction
RB Fenwick, LJ Campbell, K Rajasekar, S Prasannan, D Nietlispach, ...
Structure 18 (8), 985-995, 2010
352010
Accurate scoring of non-uniform sampling schemes for quantitative NMR
PC Aoto, RB Fenwick, GJA Kroon, PE Wright
Journal of Magnetic Resonance 246, 31-35, 2014
322014
Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway
D Oyen, RB Fenwick, RL Stanfield, HJ Dyson, PE Wright
Journal of the American Chemical Society 137 (29), 9459-9468, 2015
272015
Average conformations determined from PRE data provide high-resolution maps of transient tertiary interactions in disordered proteins
J Silvestre-Ryan, CW Bertoncini, RB Fenwick, S Esteban-Martin, ...
Biophysical journal 104 (8), 1740-1751, 2013
202013
Correlated inter-domain motions in adenylate kinase
S Esteban-Martín, RB Fenwick, J Ådén, B Cossins, CW Bertoncini, ...
PLoS computational biology 10 (7), e1003721, 2014
172014
Kinetics of the Antibody Recognition Site in the Third IgG‐Binding Domain of Protein G
S Pratihar, TM Sabo, D Ban, RB Fenwick, S Becker, X Salvatella, ...
Angewandte Chemie International Edition 55 (33), 9567-9570, 2016
152016
NMR reveals a dynamic allosteric pathway in thrombin
LD Handley, B Fuglestad, K Stearns, M Tonelli, RB Fenwick, ...
Scientific reports 7, 39575, 2017
132017
Regulation of androgen receptor activity by transient interactions of its transactivation domain with general transcription regulators
E De Mol, E Szulc, C Di Sanza, P Martínez-Cristóbal, CW Bertoncini, ...
Structure 26 (1), 145-152. e3, 2018
112018
Direct investigation of slow correlated dynamics in proteins via dipolar interactions
RB Fenwick, CD Schwieters, B Vögeli
Journal of the American Chemical Society 138 (27), 8412-8421, 2016
112016
Influence of experimental uncertainties on the properties of ensembles derived from NMR residual dipolar couplings
RB Fenwick, S Esteban-Martín, X Salvatella
The Journal of Physical Chemistry Letters 1 (24), 3438-3441, 2010
102010
Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion
D Oyen, RB Fenwick, PC Aoto, RL Stanfield, IA Wilson, HJ Dyson, ...
Journal of the American Chemical Society 139 (32), 11233-11240, 2017
92017
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Articles 1–20