Follow
Pekka Jaako
Pekka Jaako
Verified email at gu.se - Homepage
Title
Cited by
Cited by
Year
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia
P Jaako, J Flygare, K Olsson, R Quere, M Ehinger, A Henson, S Ellis, ...
Blood, The Journal of the American Society of Hematology 118 (23), 6087-6096, 2011
1462011
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia
P Jaako, S Debnath, K Olsson, D Bryder, J Flygare, S Karlsson
Blood, The Journal of the American Society of Hematology 120 (11), 2225-2228, 2012
932012
Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture
S Singbrant, G Karlsson, M Ehinger, K Olsson, P Jaako, K Miharada, ...
Blood, The Journal of the American Society of Hematology 115 (23), 4689-4698, 2010
702010
Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation
A Ugale, GL Norddahl, M Wahlestedt, P Säwén, P Jaako, CJ Pronk, ...
Cell reports 9 (4), 1246-1255, 2014
652014
EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome
S Tan, L Kermasson, A Hoslin, P Jaako, A Faille, A Acevedo-Arozena, ...
Blood, The Journal of the American Society of Hematology 134 (3), 277-290, 2019
512019
Disruption of the 5S RNP–Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia
P Jaako, S Debnath, K Olsson, Y Zhang, J Flygare, MS Lindström, ...
Leukemia 29 (11), 2221-2229, 2015
392015
Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia
P Jaako, S Debnath, K Olsson, U Modlich, M Rothe, A Schambach, ...
Haematologica 99 (12), 1792, 2014
362014
Lentiviral vectors with cellular promoters correct anemia and lethal bone marrow failure in a mouse model for Diamond-Blackfan anemia
S Debnath, P Jaako, K Siva, M Rothe, J Chen, M Dahl, HB Gaspar, ...
Molecular Therapy 25 (8), 1805-1814, 2017
262017
eIF6 rebinding dynamically couples ribosome maturation and translation
P Jaako, A Faille, S Tan, CC Wong, N Escudero-Urquijo, ...
Nature Communications 13 (1), 1562, 2022
242022
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond–Blackfan anaemia
SE Sjögren, K Siva, S Soneji, AJ George, M Winkler, P Jaako, ...
British Journal of Haematology 171 (4), 517-529, 2015
242015
SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q-myelodysplastic syndrome
K Siva, P Jaako, K Miharada, E Rörby, M Ehinger, G Karlsson, S Karlsson
Leukemia 26 (11), 2416-2419, 2012
202012
Diamond-Blackfan anemia: pathogenesis, management and development of future therapies
P Jaako, J Flygare, S Karlsson
Hematology education: the education program for the annual congress of the …, 2013
92013
Induction of the 5S RNP–Mdm2–p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia
P Jaako, A Ugale, M Wahlestedt, T Velasco-Hernandez, J Cammenga, ...
Leukemia 31 (1), 213-221, 2017
72017
Ducou le Pointe H, Fumagalli S, Beaupain B, Nitschké P, Bôle-Feysot C, de Villartay JP, Bellanné-Chantelot C, Donadieu J, Kannengiesser C, Warren AJ, Revy P. EFL1 mutations …
S Tan, L Kermasson, A Hoslin, P Jaako, A Faille, A Acevedo-Arozena, ...
Blood 134 (3), 277-290, 2019
62019
The chemical landscape of the human ribosome at 1.67 Å resolution
A Faille, KC Dent, S Pellegrino, P Jaako, AJ Warren
bioRxiv, 2023.02. 28.530191, 2023
32023
Glucocorticoids reduce expression of p53 target genes and reverse anemia in a mouse model of Diamond-Blackfan anemia
S Sjögren, P Jaako, S Karlsson, J Flygare
Blood, The Journal of the American Society of Hematology 122 (21), 3703-3703, 2013
32013
A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E/Proerythroblast Transition.
P Jaako, J Flygare, K Olsson, A Schambach, C Baum, J Larsson, D Bryder, ...
Blood 114 (22), 178, 2009
32009
Bone marrow failure in RPS19-deficient mice is partly caused by p53 activation and responds to L-Leucine treatment
P Jaako, S Debnath, K Olsson, J Flygare, S Karlsson
Blood 118 (21), 727, 2011
22011
Chronic RPS19 deficiency leads to bone marrow failure in a mouse model for Diamond-Blackfan anemia
P Jaako, J Flygare, K Olsson, R Quere, J Larsson, D Bryder, S Karlsson
Blood 116 (21), 193, 2010
22010
Defective ribosome assembly impairs leukemia stem cell function in a murine model of acute myeloid leukemia
D Sjövall, S Ghosh, J Hansson, C Guibentif, P Jaako
bioRxiv, 2023.01. 22.525120, 2023
12023
The system can't perform the operation now. Try again later.
Articles 1–20