| Multiple roles of HDAC inhibition in neurodegenerative conditions DM Chuang, Y Leng, Z Marinova, HJ Kim, CT Chiu Trends in neurosciences 32 (11), 591-601, 2009 | 727 | 2009 |
| Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons E Chalecka-Franaszek, DM Chuang Proceedings of the National Academy of Sciences 96 (15), 8745-8750, 1999 | 678 | 1999 |
| Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action HJ Kim, M Rowe, M Ren, JS Hong, PS Chen, DM Chuang Journal of Pharmacology and Experimental Therapeutics 321 (3), 892-901, 2007 | 629 | 2007 |
| Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression: a prominent role in neuroprotection against excitotoxicity RW Chen, DM Chuang Journal of Biological Chemistry 274 (10), 6039-6042, 1999 | 582 | 1999 |
| Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx S Nonaka, CJ Hough, DM Chuang Proceedings of the National Academy of Sciences 95 (5), 2642-2647, 1998 | 562 | 1998 |
| Therapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorder CT Chiu, Z Wang, JG Hunsberger, DM Chuang Pharmacological reviews 65 (1), 105-142, 2013 | 452 | 2013 |
| Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction M Ren, Y Leng, MR Jeong, PR Leeds, DM Chuang Journal of neurochemistry 89 (6), 1358-1367, 2004 | 438 | 2004 |
| Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes PS Chen, GS Peng, G Li, S Yang, X Wu, CC Wang, B Wilson, RB Lu, ... Molecular psychiatry 11 (12), 1116-1125, 2006 | 412 | 2006 |
| The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons S Yasuda, MH Liang, Z Marinova, A Yahyavi, DM Chuang Molecular psychiatry 14 (1), 51-59, 2009 | 392 | 2009 |
| Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases DM Chuang, C Hough, VV Senatorov Annu. Rev. Pharmacol. Toxicol. 45, 269-290, 2005 | 384 | 2005 |
| Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation R Hashimoto, C Hough, T Nakazawa, T Yamamoto, DM Chuang Journal of neurochemistry 80 (4), 589-597, 2002 | 377 | 2002 |
| Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity R Hashimoto, N Takei, K Shimazu, L Christ, B Lu, DM Chuang Neuropharmacology 43 (7), 1173-1179, 2002 | 346 | 2002 |
| The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain HJ Kim, P Leeds, DM Chuang Journal of neurochemistry 110 (4), 1226-1240, 2009 | 344 | 2009 |
| Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons X Wu, PS Chen, S Dallas, B Wilson, ML Block, CC Wang, H Kinyamu, ... International Journal of Neuropsychopharmacology 11 (8), 1123-1134, 2008 | 335 | 2008 |
| Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats S Nonaka, DM Chuang Neuroreport 9 (9), 2081-2084, 1998 | 331 | 1998 |
| Neuroprotective effects of lithium in cultured cells and animal models of diseases DM Chuang, RW Chen, E Chalecka‐Franaszek, M Ren, R Hashimoto, ... Bipolar disorders 4 (2), 129-136, 2002 | 315 | 2002 |
| Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity PS Chen, CC Wang, CD Bortner, GS Peng, X Wu, H Pang, RB Lu, ... Neuroscience 149 (1), 203-212, 2007 | 295 | 2007 |
| Nuclear factor κB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum ZH Qin, RW Chen, Y Wang, M Nakai, DM Chuang, TN Chase Journal of Neuroscience 19 (10), 4023-4033, 1999 | 284 | 1999 |
| Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders CT Chiu, DM Chuang Pharmacology & therapeutics 128 (2), 281-304, 2010 | 268 | 2010 |
| Evidence that glyceraldehyde‐3‐phosphate dehydrogenase is involved in age‐induced apoptosis in mature cerebellar neurons in culture R Ishitani, K Sunaga, A Hirano, P Saunders, N Katsube, DM Chuang Journal of neurochemistry 66 (3), 928-935, 1996 | 267 | 1996 |
