Leonard Amaral
Leonard Amaral
Professor Emeritus, Institute of Hygiene and Tropical Medicine of Lisbom
Verified email at ihmt.unl.pt
TitleCited byYear
Mechanisms of drug efflux and strategies to combat them: challenging the efflux pump of Gram-negative bacteria
JM Pagès, L Amaral
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (5), 826-833, 2009
Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis
D Ordway, M Viveiros, C Leandro, R Bettencourt, J Almeida, M Martins, ...
Antimicrobial agents and chemotherapy 47 (3), 917-922, 2003
Antibiotic stress, genetic response and altered permeability of E. coli
M Viveiros, M Dupont, L Rodrigues, I Couto, A Davin-Regli, M Martins, ...
PloS one 2 (4), 2007
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis
D Machado, I Couto, J Perdigao, L Rodrigues, I Portugal, P Baptista, ...
PloS one 7 (4), 2012
The potential management of resistant infections with non-antibiotics.
JE Kristiansen, L Amaral
The Journal of antimicrobial chemotherapy 40 (3), 319-327, 1997
Geraniol restores antibiotic activities against multidrug-resistant isolates from gram-negative species
V Lorenzi, A Muselli, AF Bernardini, L Berti, JM Pagès, L Amaral, JM Bolla
Antimicrobial agents and chemotherapy 53 (5), 2209-2211, 2009
Multidrug efflux pumps in Staphylococcus aureus: an update
SS Costa, M Viveiros, L Amaral, I Couto
The open microbiology journal 7, 59, 2013
Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities
M Martins, SG Dastidar, S Fanning, JE Kristiansen, J Molnar, JM Pages, ...
International journal of antimicrobial agents 31 (3), 198-208, 2008
Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of …
L Amaral, JE Kristiansen, M Viveiros, J Atouguia
Journal of Antimicrobial Chemotherapy 47 (5), 505-511, 2001
Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: potential use for initial therapy of freshly diagnosed …
L Amaral, JE Kristiansen, LS Abebe, W Millett
Journal of Antimicrobial Chemotherapy 38 (6), 1049-1053, 1996
Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps
L Amaral, M Martins, M Viveiros
Journal of antimicrobial chemotherapy 59 (6), 1237-1246, 2007
Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines
M Viveiros, L Amaral
International journal of antimicrobial agents 17 (3), 225-228, 2001
Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and expression of proton gradient-dependent multidrug efflux pump genes
M Viveiros, A Jesus, M Brito, C Leandro, M Martins, D Ordway, AM Molnar, ...
Antimicrobial agents and chemotherapy 49 (8), 3578-3582, 2005
Antimicrobial activity of phenothiazines
in vivo 18 (6), 725-732, 2004
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis
M Viveiros, I Portugal, R Bettencourt, TC Victor, AM Jordaan, C Leandro, ...
Antimicrobial agents and chemotherapy 46 (9), 2804-2810, 2002
Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis.
L Rodrigues, D Wagner, M Viveiros, D Sampaio, I Couto, M Vavra, ...
Journal of Antimicrobial Chemotherapy (JAC) 61 (5), 2008
Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex
L Rodrigues, D Machado, I Couto, L Amaral, M Viveiros
Infection, Genetics and Evolution 12 (4), 695-700, 2012
Inhibition of quorum‐sensing signals by essential oils
MÁ Szabó, GZ Varga, J Hohmann, Z Schelz, E Szegedi, L Amaral, ...
Phytotherapy Research: An International Journal Devoted to Pharmacological …, 2010
Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method
M Viveiros, A Martins, L Paixão, L Rodrigues, M Martins, I Couto, ...
International journal of antimicrobial agents 31 (5), 458-462, 2008
Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli
L Paixão, L Rodrigues, I Couto, M Martins, P Fernandes, CC De Carvalho, ...
Journal of Biological Engineering 3 (1), 18, 2009
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