Marco Osterwalder
Marco Osterwalder
Assistant Professor, Department for Biomedical Research (DBMR), University of Bern
Email confirmado em dbmr.unibe.ch
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Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions
DG Lupiáñez, K Kraft, V Heinrich, P Krawitz, F Brancati, E Klopocki, ...
Cell 161 (5), 1012-1025, 2015
14042015
Enhancer redundancy provides phenotypic robustness in mammalian development
M Osterwalder, I Barozzi, V Tissières, Y Fukuda-Yuzawa, BJ Mannion, ...
Nature 554 (7691), 239-243, 2018
3122018
Progressive loss of function in a limb enhancer during snake evolution
EZ Kvon, OK Kamneva, US Melo, I Barozzi, M Osterwalder, BJ Mannion, ...
Cell 167 (3), 633-642. e11, 2016
1802016
Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development
A Galli, D Robay, M Osterwalder, X Bao, JD Bénazet, M Tariq, R Paro, ...
PLoS genetics 6 (4), e1000901, 2010
1362010
Ultraconserved enhancers are required for normal development
DE Dickel, AR Ypsilanti, R Pla, Y Zhu, I Barozzi, BJ Mannion, YS Khin, ...
Cell 172 (3), 491-499. e15, 2018
1282018
GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis
J Lopez-Rios, D Speziale, D Robay, M Scotti, M Osterwalder, ...
Developmental cell 22 (4), 837-848, 2012
862012
Dual RMCE for efficient re-engineering of mouse mutant alleles
M Osterwalder, A Galli, B Rosen, WC Skarnes, R Zeller, J Lopez-Rios
Nature methods 7 (11), 893-895, 2010
782010
HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme
M Osterwalder, D Speziale, M Shoukry, R Mohan, R Ivanek, M Kohler, ...
Developmental cell 31 (3), 345-357, 2014
772014
Genome-wide compendium and functional assessment of in vivo heart enhancers
DE Dickel, I Barozzi, Y Zhu, Y Fukuda-Yuzawa, M Osterwalder, ...
Nature communications 7 (1), 1-13, 2016
752016
Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog)
AJ Will, G Cova, M Osterwalder, WL Chan, L Wittler, N Brieske, V Heinrich, ...
Nature Genetics 49 (10), 1539-1545, 2017
732017
Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13
R Sheth, I Barozzi, D Langlais, M Osterwalder, S Nemec, HL Carlson, ...
Cell reports 17 (11), 2913-2926, 2016
522016
Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium
NJ VanDusen, J Casanovas, JW Vincentz, BA Firulli, M Osterwalder, ...
Cell reports 9 (6), 2071-2083, 2014
472014
Cardiac reprogramming factors synergistically activate genome-wide cardiogenic stage-specific enhancers
H Hashimoto, Z Wang, GA Garry, VS Malladi, GA Botten, W Ye, H Zhou, ...
Cell stem cell 25 (1), 69-86. e5, 2019
422019
Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos
J Itou, H Kawakami, T Quach, M Osterwalder, SM Evans, R Zeller, ...
Development 139 (9), 1620-1629, 2012
422012
HAND2 target gene regulatory networks control atrioventricular canal and cardiac valve development
F Laurent, A Girdziusaite, J Gamart, I Barozzi, M Osterwalder, JA Akiyama, ...
Cell reports 19 (8), 1602-1613, 2017
372017
Loss of extreme long-range enhancers in human neural crest drives a craniofacial disorder
HK Long, M Osterwalder, IC Welsh, K Hansen, JOJ Davies, YE Liu, ...
Cell Stem Cell 27 (5), 765-783. e14, 2020
142020
Limb-Enhancer Genie: An accessible resource of accurate enhancer predictions in the developing limb
R Monti, I Barozzi, M Osterwalder, E Lee, M Kato, TH Garvin, ...
PLoS computational biology 13 (8), e1005720, 2017
142017
Noncoding deletions reveal a gene that is critical for intestinal function
D Oz-Levi, T Olender, I Bar-Joseph, Y Zhu, D Marek-Yagel, I Barozzi, ...
Nature 571 (7763), 107-111, 2019
132019
A unique stylopod patterning mechanism by Shox2-controlled osteogenesis
W Ye, Y Song, Z Huang, M Osterwalder, A Ljubojevic, J Xu, B Bobick, ...
Development 143 (14), 2548-2560, 2016
132016
Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors
S Kult, T Olender, M Osterwalder, S Markman, D Leshkowitz, S Krief, ...
Elife 10, e55361, 2021
62021
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