Maria Ciofani
Maria Ciofani
Duke University Medical Center
Verified email at
Cited by
Cited by
A validated regulatory network for Th17 cell specification
M Ciofani, A Madar, C Galan, ML Sellars, K Mace, F Pauli, A Agarwal, ...
Cell 151 (2), 289-303, 2012
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
T Palomero, ML Sulis, M Cortina, PJ Real, K Barnes, M Ciofani, ...
Nature medicine 13 (10), 1203-1210, 2007
Notch promotes survival of pre–T cells at the β-selection checkpoint by regulating cellular metabolism
M Ciofani, JC Zuniga-Pflücker
Nature immunology 6 (9), 881-888, 2005
Digoxin and its derivatives suppress TH 17 cell differentiation by antagonizing RORγt activity
JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ...
Nature 472 (7344), 486-490, 2011
Maintenance of T cell specification and differentiation requires recurrent notch receptor–ligand interactions
TM Schmitt, M Ciofani, HT Petrie, JC Zúñiga-Pflücker
The Journal of experimental medicine 200 (4), 469-479, 2004
Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation
M Ciofani, TM Schmitt, A Ciofani, AM Michie, N Çuburu, A Aublin, ...
The Journal of Immunology 172 (9), 5230-5239, 2004
A genomic regulatory element that directs assembly and function of immune-specific AP-1–IRF complexes
E Glasmacher, S Agrawal, AB Chang, TL Murphy, W Zeng, B Vander Lugt, ...
Science 338 (6109), 975-980, 2012
Stage-specific and differential notch dependency at the αβ and γδ T lineage bifurcation
M Ciofani, GC Knowles, DL Wiest, H von Boehmer, JC Zúñiga-Pflücker
Immunity 25 (1), 105-116, 2006
The thymus as an inductive site for T lymphopoiesis
M Ciofani, JC Zúñiga-Pflücker
Annu. Rev. Cell Dev. Biol. 23, 463-493, 2007
Determining γδ versus αβ T cell development
M Ciofani, JC Zúñiga-Pflücker
Nature Reviews Immunology 10 (9), 657-663, 2010
The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival
M Mandal, C Borowski, T Palomero, AA Ferrando, P Oberdoerffer, F Meng, ...
The Journal of experimental medicine 201 (4), 603-614, 2005
Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death
H Okada, C Bakal, A Shahinian, A Elia, A Wakeham, WK Suh, GS Duncan, ...
The Journal of experimental medicine 199 (3), 399-410, 2004
Marked induction of the helix-loop-helix protein Id3 promotes the γδ T cell fate and renders their functional maturation Notch independent
JPH Lauritsen, GW Wong, SY Lee, JM Lefebvre, M Ciofani, M Rhodes, ...
Immunity 31 (4), 565-575, 2009
Dynamic microRNA gene transcription and processing during T cell development
FF Kirigin, K Lindstedt, M Sellars, M Ciofani, SL Low, L Jones, F Bell, ...
The Journal of Immunology 188 (7), 3257-3267, 2012
Low activation threshold as a mechanism for ligand-independent signaling in pre-T cells
MC Haks, SM Belkowski, M Ciofani, M Rhodes, JM Lefebvre, S Trop, ...
The Journal of Immunology 170 (6), 2853-2861, 2003
Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells
MMW Chong, N Simpson, M Ciofani, G Chen, A Collins, DR Littman
Genes & development 24 (7), 659-669, 2010
JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation
TM Carr, JD Wheaton, GM Houtz, M Ciofani
Nature communications 8 (1), 1-18, 2017
A survival guide to early T cell development
M Ciofani, JC Zúñiga-Pflücker
Immunologic research 34 (2), 117-132, 2006
Leveraging chromatin accessibility for transcriptional regulatory network inference in T Helper 17 Cells
ER Miraldi, M Pokrovskii, A Watters, DM Castro, N De Veaux, JA Hall, ...
Genome research 29 (3), 449-463, 2019
The transcription factor c-Maf is essential for the commitment of IL-17-producing γδ T cells
MK Zuberbuehler, ME Parker, JD Wheaton, JR Espinosa, HR Salzler, ...
Nature immunology 20 (1), 73-85, 2019
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