Immunity, hypoxia, and metabolism–the Ménage à Trois of cancer: implications for immunotherapy C Riera-Domingo, A Audigé, S Granja, WC Cheng, PC Ho, F Baltazar, ... Physiological reviews 100 (1), 1-102, 2020 | 217 | 2020 |
Lactate beyond a waste metabolite: metabolic affairs and signaling in malignancy F Baltazar, J Afonso, M Costa, S Granja Frontiers in Oncology 10, 231, 2020 | 119 | 2020 |
Targeting lactate transport suppresses in vivo breast tumour growth F Morais-Santos, S Granja, V Miranda-Gonçalves, AHJ Moreira, ... Oncotarget 6 (22), 19177, 2015 | 116 | 2015 |
Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas V Miranda-Gonçalves, S Granja, O Martinho, M Honavar, M Pojo, ... Oncotarget 7 (29), 46335, 2016 | 112 | 2016 |
Value of pH regulators in the diagnosis, prognosis and treatment of cancer S Granja, D Tavares-Valente, O Queirós, F Baltazar Seminars in cancer biology 43, 17-34, 2017 | 111 | 2017 |
Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status S Granja, I Marchiq, R Le Floch, CS Moura, F Baltazar, J Pouysségur Oncotarget 6 (9), 6708, 2015 | 83 | 2015 |
Glucose addiction in cancer therapy: advances and drawbacks S Granja, C Pinheiro, R Manuel Reis, O Martinho, F Baltazar Current drug metabolism 16 (3), 221-242, 2015 | 70 | 2015 |
Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas O Martinho, S Granja, T Jaraquemada, C Caeiro, V Miranda-Gonçalves, ... PloS one 7 (1), e30769, 2012 | 69 | 2012 |
RKIP inhibition in cervical cancer is associated with higher tumor aggressive behavior and resistance to cisplatin therapy O Martinho, F Pinto, S Granja, V Miranda-Gonçalves, MAR Moreira, ... PloS one 8 (3), e59104, 2013 | 68 | 2013 |
Fucoidan from Fucus vesiculosus inhibits new blood vessel formation and breast tumor growth in vivo C Oliveira, S Granja, NM Neves, RL Reis, F Baltazar, TH Silva, A Martins Carbohydrate polymers 223, 115034, 2019 | 58 | 2019 |
Prognostic significance of monocarboxylate transporter expression in oral cavity tumors S Simoes-Sousa, S Granja, C Pinheiro, D Fernandes, A Longatto-Filho, ... Cell Cycle 15 (14), 1865-1873, 2016 | 52 | 2016 |
Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction I Marchiq, J Albrengues, S Granja, C Gaggioli, J Pouysségur, MP Simon Oncotarget 6 (28), 24636, 2015 | 48 | 2015 |
Impact of mesenchymal stem cells’ secretome on glioblastoma pathophysiology J Vieira de Castro, ED Gomes, S Granja, SI Anjo, F Baltazar, B Manadas, ... Journal of Translational Medicine 15, 1-14, 2017 | 46 | 2017 |
Lactate and lactate transporters as key players in the maintenance of the Warburg effect A Pereira-Nunes, J Afonso, S Granja, F Baltazar Tumor microenvironment: the main driver of metabolic adaptation, 51-74, 2020 | 44 | 2020 |
Metabolic reprogramming: a new relevant pathway in adult adrenocortical tumors C Pinheiro, S Granja, A Longatto-Filho, AM Faria, MCBV Fragoso, ... Oncotarget 6 (42), 44403, 2015 | 42 | 2015 |
HER family receptors are important theranostic biomarkers for cervical cancer: blocking glucose metabolism enhances the therapeutic effect of HER inhibitors O Martinho, R Silva-Oliveira, FP Cury, AM Barbosa, S Granja, ... Theranostics 7 (3), 717, 2017 | 38 | 2017 |
Modulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route NN Ferreira, S Granja, FI Boni, FG Prezotti, LMB Ferreira, BSF Cury, ... Drug Delivery and Translational Research 10, 1729-1747, 2020 | 34 | 2020 |
Metabolic alterations underlying Bevacizumab therapy in glioblastoma cells V Miranda-Gonçalves, D Cardoso-Carneiro, I Valbom, FP Cury, VA Silva, ... Oncotarget 8 (61), 103657, 2017 | 32 | 2017 |
Nose-to-brain co-delivery of drugs for glioblastoma treatment using nanostructured system NN Ferreira, E de Oliveira Junior, S Granja, FI Boni, LMB Ferreira, ... International journal of pharmaceutics 603, 120714, 2021 | 31 | 2021 |
IL-17A and IL-17F orchestrate macrophages to promote lung cancer N Ferreira, I Mesquita, F Baltazar, R Silvestre, S Granja Cellular Oncology 43, 643-654, 2020 | 31 | 2020 |