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Jernej Ule
Jernej Ule
The Francis Crick Institute, UK Dementia Research Institute at King's, Institute of Chemistry
Email confirmado em crick.ac.uk - Página inicial
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HITS-CLIP yields genome-wide insights into brain alternative RNA processing
DD Licatalosi, A Mele, JJ Fak, J Ule, M Kayikci, SW Chi, TA Clark, ...
Nature 456 (7221), 464-469, 2008
15572008
CLIP identifies Nova-regulated RNA networks in the brain
J Ule, KB Jensen, M Ruggiu, A Mele, A Ule, RB Darnell
Science 302 (5648), 1212-1215, 2003
13252003
iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
J König, K Zarnack, G Rot, T Curk, M Kayikci, B Zupan, DJ Turner, ...
Nature structural & molecular biology 17 (7), 909-915, 2010
12242010
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
JR Tollervey, T Curk, B Rogelj, M Briese, M Cereda, M Kayikci, J König, ...
Nature neuroscience 14 (4), 452-458, 2011
12172011
CLIP: a method for identifying protein–RNA interaction sites in living cells
J Ule, K Jensen, A Mele, RB Darnell
Methods 37 (4), 376-386, 2005
7292005
An RNA map predicting Nova-dependent splicing regulation
J Ule, G Stefani, A Mele, M Ruggiu, X Wang, B Taneri, T Gaasterland, ...
Nature 444 (7119), 580-586, 2006
6682006
TDP‐43 regulates its mRNA levels through a negative feedback loop
YM Ayala, L De Conti, SE Avendaño‐Vázquez, A Dhir, M Romano, ...
The EMBO journal 30 (2), 277-288, 2011
6392011
Nova regulates brain-specific splicing to shape the synapse
J Ule, A Ule, J Spencer, A Williams, JS Hu, M Cline, H Wang, T Clark, ...
Nature genetics 37 (8), 844-852, 2005
5932005
Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic
YB Lee, HJ Chen, JN Peres, J Gomez-Deza, J Attig, M Štalekar, ...
Cell reports 5 (5), 1178-1186, 2013
5532013
Alternative splicing regulatory networks: functions, mechanisms, and evolution
J Ule, BJ Blencowe
Molecular cell 76 (2), 329-345, 2019
5412019
Aberrant methylation of t RNA s links cellular stress to neuro‐developmental disorders
S Blanco, S Dietmann, JV Flores, S Hussain, C Kutter, P Humphreys, ...
The EMBO journal 33 (18), 2020-2039, 2014
5372014
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes
D Blazek, J Kohoutek, K Bartholomeeusen, E Johansen, P Hulinkova, ...
Genes & development 25 (20), 2158-2172, 2011
5092011
NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs
S Hussain, AA Sajini, S Blanco, S Dietmann, P Lombard, Y Sugimoto, ...
Cell reports 4 (2), 255-261, 2013
5012013
Direct competition between hnRNP C and U2AF65 protects the transcriptome from the exonization of Alu elements
K Zarnack, J König, M Tajnik, I Martincorena, S Eustermann, I Stévant, ...
Cell 152 (3), 453-466, 2013
4902013
iCLIP: protein–RNA interactions at nucleotide resolution
I Huppertz, J Attig, A D’Ambrogio, LE Easton, CR Sibley, Y Sugimoto, ...
Methods 65 (3), 274-287, 2014
4782014
Protein–RNA interactions: new genomic technologies and perspectives
J König, K Zarnack, NM Luscombe, J Ule
Nature Reviews Genetics 13 (2), 77-83, 2012
4652012
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing
MM Pradeepa, HG Sutherland, J Ule, GR Grimes, WA Bickmore
PLoS genetics 8 (5), e1002717, 2012
3752012
Major shifts in glial regional identity are a transcriptional hallmark of human brain aging
L Soreq, J Rose, E Soreq, J Hardy, D Trabzuni, MR Cookson, C Smith, ...
Cell reports 18 (2), 557-570, 2017
3652017
Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43
PJ Lukavsky, D Daujotyte, JR Tollervey, J Ule, C Stuani, E Buratti, ...
Nature structural & molecular biology 20 (12), 1443-1449, 2013
3482013
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
B Rogelj, LE Easton, GK Bogu, LW Stanton, G Rot, T Curk, B Zupan, ...
Scientific reports 2 (1), 603, 2012
3272012
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