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Yan Gu
Yan Gu
Iowa State University; Harvard University; Bristol-Myers Squibb; Takeda Pharmaceuticals
Email confirmado em g.harvard.edu
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Manganese nanoparticle activates mitochondrial dependent apoptotic signaling and autophagy in dopaminergic neuronal cells
HA Ngwa, A Kanthasamy, Y Gu, N Fang, V Anantharam, AG Kanthasamy
Toxicology and applied pharmacology 256 (3), 227-240, 2011
1682011
Single particle orientation and rotation tracking discloses distinctive rotational dynamics of drug delivery vectors on live cell membranes
Y Gu, W Sun, G Wang, N Fang
Journal of the American Chemical Society 133 (15), 5720-5723, 2011
1192011
Technology outlook for real‐time quality attribute and process parameter monitoring in biopharmaceutical development—A review
DP Wasalathanthri, MS Rehmann, Y Song, Y Gu, L Mi, C Shao, ...
Biotechnology and Bioengineering 117 (10), 3182-3198, 2020
1062020
Rotational dynamics of cargos at pauses during axonal transport
Y Gu, W Sun, G Wang, K Jeftinija, S Jeftinija, N Fang
Nature communications 3 (1), 1030, 2012
792012
Three-dimensional super-localization and tracking of single gold nanoparticles in cells
Y Gu, X Di, W Sun, G Wang, N Fang
Analytical chemistry 84 (9), 4111-4117, 2012
752012
Characteristic rotational behaviors of rod-shaped cargo revealed by automated five-dimensional single particle tracking
K Chen, Y Gu, W Sun, G Wang, X Fan, T Xia, N Fang
Nature Communications, 2017
692017
Revealing rotational modes of functionalized gold nanorods on live cell membranes
Y Gu, W Sun, G Wang, MT Zimmermann, RL Jernigan, N Fang
Small 9 (5), 785-792, 2013
392013
Single particle orientation and rotational tracking (SPORT) in biophysical studies
Y Gu, JW Ha, AE Augspurger, K Chen, S Zhu, N Fang
Nanoscale 5 (22), 10753-10764, 2013
392013
Simultaneous single-particle superlocalization and rotational tracking
Y Gu, G Wang, N Fang
ACS nano 7 (2), 1658-1665, 2013
342013
Purity Determination by Capillary Electrophoresis Sodium Hexadecyl Sulfate (CE-SHS): A Novel application For Therapeutic Protein Characterization
J Beckman, Y Song, Y Gu, S Voronov, N Chennamsetty, SR Krystek, ...
Analytical Chemistry, 2018
322018
Wavelength-dependent differential interference contrast microscopy: multiplexing detection using nonfluorescent nanoparticles
Y Luo, W Sun, Y Gu, G Wang, N Fang
Analytical chemistry 82 (15), 6675-6679, 2010
322010
Dynamin-dependent vesicle twist at the final stage of clathrin-mediated endocytosis
X Cheng, K Chen, B Dong, M Yang, SL Filbrun, Y Myoung, TX Huang, ...
Nature cell biology 23 (8), 859-869, 2021
302021
Dual-modality single particle orientation and rotational tracking of intracellular transport of nanocargos
W Sun, Y Gu, G Wang, N Fang
Analytical chemistry 84 (2), 1134-1138, 2012
242012
Localization accuracy of gold nanoparticles in single particle orientation and rotational tracking
F Zhao, K Chen, B Dong, K Yang, Y Gu, N Fang
Optics Express 25 (9), 2017
162017
Therapeutic protein purity and fragmented species characterization by capillary electrophoresis sodium dodecyl sulfate using systematic hybrid cleavage and forced degradation
L Duhamel, Y Gu, G Barnett, Y Tao, S Voronov, J Ding, N Mussa, ZJ Li
Analytical and bioanalytical chemistry 411, 5617-5629, 2019
152019
Understanding nanoparticle drug delivery from rotational dynamics and behaviors of functionalized gold nanorods on live cell membranes
Y Gu, W Sun, G Wang, N Fang
Biophysical Journal 100 (3), 473a, 2011
92011
Assessment of CE-based baseline disturbances using simulation and targeted experimental evaluation—impact on the purity determination of therapeutic proteins
Y Gu, S Voronov, J Ding, N Mussa, ZJ Li
Analytical and bioanalytical chemistry 411, 2425-2437, 2019
72019
Using Digestion by IdeS Protease to Improve Quantification of Degradants in Monoclonal Antibodies by Non-Reducing Capillary Gel Electrophoresis
A McClain, Y Zhang, Y Yin, Q Wang, LY Hwang, Y Gu, J Beckman, ...
Analytical Chemistry 94 (50), 17388-17395, 2022
22022
Principles and biophysical applications of single particle super-localization and rotational tracking
Y Gu
2013
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Artigos 1–19