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Tuomas Heikkinen
Tuomas Heikkinen
Postdoctoral Researcher, Genome-Scale Biology Research Program, University of Helsinki
Email confirmado em helsinki.fi
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Large-scale genotyping identifies 41 new loci associated with breast cancer risk
K Michailidou, P Hall, A Gonzalez-Neira, M Ghoussaini, J Dennis, ...
Nature genetics 45 (4), 353-361, 2013
12572013
Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 …
FM Blows, KE Driver, MK Schmidt, A Broeks, FE Van Leeuwen, ...
PLoS medicine 7 (5), e1000279, 2010
12422010
Breast-Cancer Risk in Families with Mutations in PALB2
AC Antoniou, S Casadei, T Heikkinen, D Barrowdale, K Pylkäs, J Roberts, ...
New England Journal of Medicine 371 (6), 497-506, 2014
10692014
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies
XR Yang, J Chang-Claude, EL Goode, FJ Couch, H Nevanlinna, RL Milne, ...
Journal of the National Cancer Institute 103 (3), 250-263, 2011
8362011
Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)
N Mavaddat, D Barrowdale, IL Andrulis, SM Domchek, D Eccles, ...
Cancer Epidemiology, Biomarkers & Prevention 21 (1), 134-147, 2012
7562012
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23. 2
S Ahmed, G Thomas, M Ghoussaini, CS Healey, MK Humphreys, R Platte, ...
Nature genetics 41 (5), 585-590, 2009
5662009
Genome-wide association studies identify four ER negative–specific breast cancer risk loci
M Garcia-Closas, FJ Couch, S Lindstrom, K Michailidou, MK Schmidt, ...
Nature genetics 45 (4), 392-398, 2013
4712013
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general …
AC Antoniou, X Wang, ZS Fredericksen, L McGuffog, R Tarrell, ...
Nature genetics 42 (10), 885-892, 2010
4062010
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
EL Goode, G Chenevix-Trench, H Song, SJ Ramus, M Notaridou, ...
Nature genetics 42 (10), 874-879, 2010
3902010
Cancer risks associated with germline PALB2 pathogenic variants: an international study of 524 families
X Yang, G Leslie, A Doroszuk, S Schneider, J Allen, B Decker, ...
Journal of clinical oncology 38 (7), 674, 2020
3472020
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
MC Southey, DE Goldgar, R Winqvist, K Pylkäs, F Couch, M Tischkowitz, ...
Journal of medical genetics 53 (12), 800-811, 2016
2382016
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium
A Broeks, MK Schmidt, ME Sherman, FJ Couch, JL Hopper, GS Dite, ...
Human molecular genetics 20 (16), 3289-3303, 2011
2002011
Aberrations of the MRE11–RAD50–NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene
J Bartkova, J Tommiska, L Oplustilova, K Aaltonen, A Tamminen, ...
Molecular oncology 2 (4), 296-316, 2008
1952008
RAD51C is a susceptibility gene for ovarian cancer
LM Pelttari, T Heikkinen, D Thompson, A Kallioniemi, J Schleutker, K Holli, ...
Human molecular genetics 20 (16), 3278-3288, 2011
1752011
The breast cancer susceptibility mutation PALB2 1592delT is associated with an aggressive tumor phenotype
T Heikkinen, H Kärkkäinen, K Aaltonen, RL Milne, P Heikkilä, ...
Clinical Cancer Research 15 (9), 3214-3222, 2009
1672009
Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers
AC Antoniou, OM Sinilnikova, L McGuffog, S Healey, H Nevanlinna, ...
Human molecular genetics 18 (22), 4442-4456, 2009
1462009
Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of …
AM Mulligan, FJ Couch, D Barrowdale, SM Domchek, D Eccles, ...
Breast Cancer Research 13, 1-20, 2011
1402011
Risk of Estrogen Receptor–Positive and–Negative Breast Cancer and Single–Nucleotide Polymorphism 2q35-rs13387042
RL Milne, J Benítez, H Nevanlinna, T Heikkinen, K Aittomäki, C Blomqvist, ...
JNCI: Journal of the National Cancer Institute 101 (14), 1012-1018, 2009
1362009
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer
CA Maxwell, J Benítez, L Gómez-Baldó, A Osorio, N Bonifaci, ...
PLoS biology 9 (11), e1001199, 2011
1342011
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
FJ Couch, KB Kuchenbaecker, K Michailidou, GA Mendoza-Fandino, ...
Nature communications 7 (1), 11375, 2016
1282016
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