James A. R. Dalton
TitleCited byYear
An evaluation of automated homology modelling methods at low target–template sequence similarity
JAR Dalton, RM Jackson
Bioinformatics 23 (15), 1901-1908, 2007
An allosteric modulator to control endogenous G protein-coupled receptors with light
S Pittolo, X Gómez-Santacana, K Eckelt, X Rovira, J Dalton, C Goudet, ...
Nature chemical biology 10 (10), 813, 2014
New model of cystic fibrosis transmembrane conductance regulator proposes active channel-like conformation
J Dalton, O Kalid, M Schushan, N Ben-Tal, J Villà-Freixa
Journal of chemical information and modeling 52 (7), 1842-1853, 2012
Calculation of helix packing angles in protein structures
JAR Dalton, I Michalopoulos, DR Westhead
Bioinformatics 19 (10), 1298-1299, 2003
Illuminating phenylazopyridines to photoswitch metabotropic glutamate receptors: from the flask to the animals
X Gómez-Santacana, S Pittolo, X Rovira, M Lopez, C Zussy, JAR Dalton, ...
ACS central science 3 (1), 81-91, 2016
Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism
JAR Dalton, I Lans, J Giraldo
BMC bioinformatics 16 (1), 124, 2015
Homology-modelling protein–ligand interactions: allowing for ligand-induced conformational change
JAR Dalton, RM Jackson
Journal of molecular biology 399 (4), 645-661, 2010
GNAO1 encephalopathy: further delineation of a severe neurodevelopmental syndrome affecting females
A Marcé-Grau, J Dalton, J López-Pisón, MC García-Jiménez, ...
Orphanet journal of rare diseases 11 (1), 38, 2016
Computational analysis of negative and positive allosteric modulator binding and function in metabotropic glutamate receptor 5 (in) activation
JAR Dalton, X Gómez-Santacana, A Llebaria, J Giraldo
Journal of chemical information and modeling 54 (5), 1476-1487, 2014
Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8: CXCR1 complex
D Helmer, I Rink, JAR Dalton, K Brahm, M Jöst, TM Nargang, W Blum, ...
RSC Advances 5 (33), 25657-25668, 2015
Structural insights into positive and negative allosteric regulation of a G protein-coupled receptor through protein-lipid interactions
A Bruzzese, C Gil, JAR Dalton, J Giraldo
Scientific reports 8 (1), 4456, 2018
Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer
J Liu, Z Zhang, D Moreno-Delgado, JAR Dalton, X Rovira, A Trapero, ...
Elife 6, e26985, 2017
Shining light on an mGlu5 photoswitchable NAM: a theoretical perspective
J AR Dalton, I Lans, X Rovira, F Malhaire, X Gómez-Santacana, S Pittolo, ...
Current neuropharmacology 14 (5), 441-454, 2016
Helix 3 acts as a conformational hinge in class A GPCR activation: An analysis of interhelical interaction energies in crystal structures
I Lans, JAR Dalton, J Giraldo
Journal of structural biology 192 (3), 545-553, 2015
A double effect molecular switch leads to a novel potent negative allosteric modulator of metabotropic glutamate receptor 5
X Gomez-Santacana, X Rovira, JA Dalton, C Goudet, JP Pin, P Gorostiza, ...
MedChemComm 5 (10), 1548-1554, 2014
Synthesis toward Bivalent Ligands for the Dopamine D2 and Metabotropic Glutamate 5 Receptors
M Qian, E Wouters, JAR Dalton, MDP Risseeuw, RAJ Crans, C Stove, ...
Journal of medicinal chemistry 61 (18), 8212-8225, 2018
Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand
JAR Dalton, JP Pin, J Giraldo
Scientific reports 7 (1), 4944, 2017
Selective protonation of acidic residues triggers opsin activation
I Lans, JAR Dalton, J Giraldo
The Journal of Physical Chemistry B 119 (30), 9510-9519, 2015
Angiotensin II type 1/adenosine A 2A receptor oligomers: A novel target for tardive dyskinesia
PA de Oliveira, JAR Dalton, M López-Cano, A Ricarte, X Morató, ...
Scientific reports 7 (1), 1857, 2017
Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation
X Gómez-Santacana, JAR Dalton, X Rovira, JP Pin, C Goudet, ...
European journal of medicinal chemistry 127, 567-576, 2017
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