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Joan Chang
Joan Chang
Research Fellow (Principal Investigator), University of Manchester
Email confirmado em manchester.ac.uk
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LOXL2-mediated matrix remodeling in metastasis and mammary gland involution
HE Barker, J Chang, TR Cox, G Lang, D Bird, M Nicolau, HR Evans, ...
Cancer research 71 (5), 1561-1572, 2011
3172011
Circadian control of the secretory pathway maintains collagen homeostasis
J Chang, R Garva, A Pickard, CYC Yeung, V Mallikarjun, J Swift, ...
Nature cell biology 22 (1), 74-86, 2020
1552020
Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer
J Chang, MC Lucas, LE Leonte, M Garcia-Montolio, LB Singh, AD Findlay, ...
Oncotarget 8 (16), 26066, 2017
1142017
Hypoxia-mediated metastasis
J Chang, J Erler
Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging …, 2014
902014
Collagen assembly at the cell surface: dogmas revisited
M Musiime, J Chang, U Hansen, KE Kadler, C Zeltz, D Gullberg
Cells 10 (3), 662, 2021
522021
Hypoxia modulates the phenotype of osteoblasts isolated from knee osteoarthritis patients, leading to undermineralized bone nodule formation
J Chang, SG Jackson, J Wardale, SW Jones
Arthritis & Rheumatology 66 (7), 1789-1799, 2014
452014
LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling
J Chang, MM Nicolau, TR Cox, D Wetterskog, JWM Martens, H E Barker, ...
Breast Cancer Research 15, 1-18, 2013
352013
Identification of hypoxia-regulated proteins using MALDI-mass spectrometry imaging combined with quantitative proteomics
MC Djidja, J Chang, A Hadjiprocopis, F Schmich, J Sinclair, M Mršnik, ...
Journal of proteome research 13 (5), 2297-2313, 2014
332014
Preservation of circadian rhythms by the protein folding chaperone, BiP
A Pickard, J Chang, N Alachkar, B Calverley, R Garva, P Arvan, QJ Meng, ...
The FASEB Journal 33 (6), 7479, 2019
302019
Discovery of re-purposed drugs that slow SARS-CoV-2 replication in human cells
A Pickard, BC Calverley, J Chang, R Garva, S Gago, Y Lu, KE Kadler
PLoS pathogens 17 (9), e1009840, 2021
252021
Collagen assembly and turnover imaged with a CRISPR-Cas9 engineered Dendra2 tag
A Pickard, A Adamson, Y Lu, J Chang, R Garva, N Hodson, KE Kadler
BioRxiv, 331496, 2018
122018
The endosome is a master regulator of plasma membrane collagen fibril assembly
J Chang, A Pickard, R Garva, Y Lu, D Gullberg, KE Kadler
82021
Altered structural expression and enzymatic activity parameters in quiescent ulcerative colitis: are these potential normalization criteria?
S Kjærgaard, MMB Damm, J Chang, LB Riis, HB Rasmussen, ...
International journal of molecular sciences 21 (5), 1887, 2020
72020
Quantification of lung metastases from in vivo mouse models
J Chang, JT Erler
Tumor Microenvironment: Study Protocols, 245-251, 2016
72016
Modeling collagen fibril self-assembly from extracellular medium in embryonic tendon
CK Revell, JA Herrera, C Lawless, Y Lu, KE Kadler, J Chang, OE Jensen
Biophysical Journal 122 (16), 3219-3237, 2023
22023
The matrix in focus: new directions in extracellular matrix research from the 2021 ASMB hybrid meeting
BA Nerger, TM Jones, KWJ Rose, A Barqué, JS Weinbaum, RJ Petrie, ...
Biology Open 11 (1), bio059156, 2022
12022
The function and diagnostic potential of adipocyte-derived factors in the tumor microenvironment
J Chang, AC Dudley
Biomarkers of the tumor microenvironment: basic studies and practical …, 2017
12017
Matrix turnover quantified in mouse tendon by isotope labelled proteomics
A Hoyle, J Chang, R O'Cualain, D Knight, QJ Meng, K Kadler, J Swift
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 104 (2), A15-A15, 2023
2023
Collagen fibril formation, the circadian clock and collagen reporters
KE Kadler, BC Calverley, J Chang, R Garva, A Pickard, CY Yeung
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 102 (2), 118-119, 2021
2021
Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis
J Chang, A Pickard, JA Herrera, S O’Keefe, M Hartshorn, R Garva, ...
bioRxiv, 2021.03. 25.436925, 2021
2021
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