Defining stem cell dynamics in models of intestinal tumor initiation L Vermeulen, E Morrissey, M Van Der Heijden, AM Nicholson, A Sottoriva, ... Science 342 (6161), 995-998, 2013 | 414 | 2013 |
Spatiotemporal analysis of human intestinal development at single-cell resolution D Fawkner-Corbett, A Antanaviciute, K Parikh, M Jagielowicz, AS Gerós, ... Cell 184 (3), 810-826. e23, 2021 | 301 | 2021 |
Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas S Kozar, E Morrissey, AM Nicholson, M van der Heijden, HI Zecchini, ... Cell stem cell 13 (5), 626-633, 2013 | 235 | 2013 |
The dynamic architecture of the metabolic switch in Streptomyces coelicolor K Nieselt, F Battke, A Herbig, P Bruheim, A Wentzel, ØM Jakobsen, ... BMC genomics 11, 1-9, 2010 | 205 | 2010 |
Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer KJ Lenos, DM Miedema, SC Lodestijn, LE Nijman, T van den Bosch, ... Nature cell biology 20 (10), 1193-1202, 2018 | 159 | 2018 |
Apc-mutant cells act as supercompetitors in intestinal tumour initiation SM van Neerven, NE de Groot, LE Nijman, BP Scicluna, MS van Driel, ... Nature 594 (7863), 436-441, 2021 | 131 | 2021 |
Single-cell proteomics reveal that quantitative changes in co-expressed lineage-specific transcription factors determine cell fate CG Palii, Q Cheng, MA Gillespie, P Shannon, M Mazurczyk, G Napolitani, ... Cell stem cell 24 (5), 812-820. e5, 2019 | 117 | 2019 |
Fixation and spread of somatic mutations in adult human colonic epithelium AM Nicholson, C Olpe, A Hoyle, AS Thorsen, T Rus, M Colombé, ... Cell stem cell 22 (6), 909-918. e8, 2018 | 110 | 2018 |
Phospho-regulation of ATOH1 is required for plasticity of secretory progenitors and tissue regeneration G Tomic, E Morrissey, S Kozar, S Ben-Moshe, A Hoyle, R Azzarelli, ... Cell stem cell 23 (3), 436-443. e7, 2018 | 86 | 2018 |
Metabolic switches and adaptations deduced from the proteomes of Streptomyces coelicolor wild type and phoP mutant grown in batch culture L Thomas, DA Hodgson, A Wentzel, K Nieselt, TE Ellingsen, J Moore, ... Molecular & Cellular Proteomics 11 (2), 2012 | 78 | 2012 |
Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells DJ Huels, L Bruens, MC Hodder, P Cammareri, AD Campbell, ... Nature communications 9 (1), 1132, 2018 | 69 | 2018 |
Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts M van der Heijden, DM Miedema, B Waclaw, VL Veenstra, MC Lecca, ... Proceedings of the National Academy of Sciences 116 (13), 6140-6145, 2019 | 64 | 2019 |
Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth SP Singh, S Janjuha, T Hartmann, Ö Kayisoglu, J Konantz, S Birke, ... Nature communications 8 (1), 664, 2017 | 62 | 2017 |
Pomelo II: finding differentially expressed genes ER Morrissey, R Diaz-Uriarte Nucleic Acids Research 37 (suppl_2), W581-W586, 2009 | 57 | 2009 |
Inferring the time-invariant topology of a nonlinear sparse gene regulatory network using fully Bayesian spline autoregression ER Morrissey, MA Juárez, KJ Denby, NJ Burroughs Biostatistics 12 (4), 682-694, 2011 | 41 | 2011 |
On reverse engineering of gene interaction networks using time course data with repeated measurements ER Morrissey, MA Juárez, KJ Denby, NJ Burroughs Bioinformatics 26 (18), 2305-2312, 2010 | 37 | 2010 |
Asterias: integrated analysis of expression and aCGH data using an open-source, web-based, parallelized software suite R Díaz-Uriarte, A Alibés, ER Morrissey, A Cañada, OM Rueda, ML Neves Nucleic acids research 35 (suppl_2), W75-W80, 2007 | 22* | 2007 |
A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes JR Harman, R Thorne, M Jamilly, M Tapia, NT Crump, S Rice, ... Genome Research 31 (7), 1159-1173, 2021 | 21 | 2021 |
The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition E Azzoni, V Frontera, G Anselmi, C Rode, C James, EM Deltcheva, ... Cell reports 37 (11), 2021 | 20 | 2021 |
Single-cell fate decisions of bipotential hematopoietic progenitors M Brand, E Morrissey Current opinion in hematology 27 (4), 232-240, 2020 | 16 | 2020 |