Darren Creek
Darren Creek
Senior Lecturer, Drug Delivery, Disposition & Dynamics, Monash Institute of Pharmaceutical Sciences
Verified email at monash.edu - Homepage
TitleCited byYear
Mass appeal: metabolite identification in mass spectrometry-focused untargeted metabolomics
WB Dunn, A Erban, RJM Weber, DJ Creek, M Brown, R Breitling, ...
Metabolomics 9 (1), 44-66, 2013
3642013
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria
SA Charman, S Arbe-Barnes, IC Bathurst, R Brun, M Campbell, ...
Proceedings of the National Academy of Sciences 108 (11), 4400-4405, 2011
3232011
Toward Global Metabolomics Analysis with Hydrophilic Interaction Liquid Chromatography–Mass Spectrometry: Improved Metabolite Identification by Retention Time Prediction
DJ Creek, A Jankevics, R Breitling, DG Watson, MP Barrett, KEV Burgess
Analytical chemistry 83 (22), 8703-8710, 2011
2532011
IDEOM: an Excel interface for analysis of LC–MS-based metabolomics data
DJ Creek, A Jankevics, KEV Burgess, R Breitling, MP Barrett
Bioinformatics 28 (7), 1048-1049, 2012
2112012
Evaluation of Coupling Reversed Phase, Aqueous Normal Phase, and Hydrophilic Interaction Liquid Chromatography with Orbitrap Mass Spectrometry for Metabolomic Studies of Human …
T Zhang, DJ Creek, MP Barrett, G Blackburn, DG Watson
Analytical chemistry 84 (4), 1994-2001, 2012
1522012
A molecular mechanism for eflornithine resistance in African trypanosomes
IM Vincent, D Creek, DG Watson, MA Kamleh, DJ Woods, PE Wong, ...
PLoS Pathogens 6 (11), e1001204, 2010
1492010
Metabolite identification: are you sure? And how do your peers gauge your confidence?
DJ Creek, WB Dunn, O Fiehn, JL Griffin, RD Hall, Z Lei, R Mistrik, ...
Metabolomics 10 (3), 350-353, 2014
1452014
Stable isotope-labeling studies in metabolomics: new insights into structure and dynamics of metabolic networks
A Chokkathukalam, DH Kim, MP Barrett, R Breitling, DJ Creek
Bioanalysis 6 (4), 511-524, 2014
1092014
Relationship between antimalarial activity and heme alkylation for spiro-and dispiro-1, 2, 4-trioxolane antimalarials
DJ Creek, WN Charman, FCK Chiu, RJ Prankerd, Y Dong, ...
Antimicrobial agents and chemotherapy 52 (4), 1291-1296, 2008
1042008
Stable isotope-assisted metabolomics for network-wide metabolic pathway elucidation
DJ Creek, A Chokkathukalam, A Jankevics, KEV Burgess, R Breitling, ...
Analytical chemistry 84 (20), 8442-8447, 2012
1012012
The Structure− Activity Relationship of the Antimalarial Ozonide Arterolane (OZ277)
Y Dong, S Wittlin, K Sriraghavan, J Chollet, SA Charman, WN Charman, ...
Journal of medicinal chemistry 53 (1), 481-491, 2009
992009
Iron and heme metabolism in Plasmodium falciparum and the mechanism of action of artemisinins
N Klonis, DJ Creek, L Tilley
Current opinion in microbiology 16 (6), 722-727, 2013
872013
Untargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei
IM Vincent, DJ Creek, K Burgess, DJ Woods, RJS Burchmore, MP Barrett
PLoS Neglected Tropical Diseases 6 (5), e1618, 2012
852012
Benznidazole Biotransformation and Multiple Targets in Trypanosoma cruzi Revealed by Metabolomics.
A Trochine, DJ Creek, P Faral-Tello, MP Barrett, C Robello
PLoS neglected tropical diseases 8 (5), e2844, 2014
822014
BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei
RD Oppenheim, DJ Creek, JI Macrae, KK Modrzynska, P Pino, ...
PLoS pathogens 10 (7), e1004263, 2014
732014
Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose.
DJ Creek, M Mazet, F Achcar, J Anderson, DH Kim, R Kamour, P Morand, ...
PLoS pathogens 11 (3), e1004689-e1004689, 2015
722015
Iron‐mediated degradation kinetics of substituted dispiro‐1, 2, 4‐trioxolane antimalarials
DJ Creek, WN Charman, FCK Chiu, RJ Prankerd, KJ McCullough, Y Dong, ...
Journal of pharmaceutical sciences 96 (11), 2945-2956, 2007
722007
Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei
DJ Creek, B Nijagal, DH Kim, F Rojas, KR Matthews, MP Barrett
Antimicrobial agents and chemotherapy 57 (6), 2768-2779, 2013
692013
mzMatch–ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data
A Chokkathukalam, A Jankevics, DJ Creek, F Achcar, MP Barrett, ...
Bioinformatics 29 (2), 281-283, 2012
682012
Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1, 2, 4-trioxolane piperidine
M Padmanilayam, B Scorneaux, Y Dong, J Chollet, H Matile, SA Charman, ...
Bioorganic & medicinal chemistry letters 16 (21), 5542-5545, 2006
572006
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