Monoclonal antibodies follow distinct aggregation pathways during production-relevant acidic incubation and neutralization T Skamris, X Tian, M Thorolfsson, HS Karkov, HB Rasmussen, ... Pharmaceutical research 33, 716-728, 2016 | 54 | 2016 |
Investigation of protein selectivity in multimodal chromatography using in silico designed Fab fragment variants HS Karkov, BO Krogh, J Woo, S Parimal, H Ahmadian, SM Cramer Biotechnology and Bioengineering 112 (11), 2305-2315, 2015 | 45 | 2015 |
Methods development in multimodal chromatography with mobile phase modifiers using the steric mass action model HS Karkov, L Sejergaard, SM Cramer Journal of Chromatography A 1318, 149-155, 2013 | 44 | 2013 |
QSAR models for prediction of chromatographic behavior of homologous Fab variants JR Robinson, HS Karkov, JA Woo, BO Krogh, SM Cramer Biotechnology and bioengineering 114 (6), 1231-1240, 2017 | 38 | 2017 |
Model‐based process development for the purification of a modified human growth hormone using multimodal chromatography L Sejergaard, HS Karkov, JK Krarup, ABB Hagel, SM Cramer Biotechnology Progress 30 (5), 1057-1064, 2014 | 31 | 2014 |
Evaluation of selectivity in homologous multimodal chromatographic systems using in silico designed antibody fragment libraries HS Karkov, J Woo, BO Krogh, H Ahmadian, SM Cramer Journal of Chromatography A 1426, 102-109, 2015 | 24 | 2015 |
Improving the developability of an antigen binding fragment by aspartate substitutions LI Sakhnini, PJ Greisen, C Wiberg, Z Bozoky, S Lund, AM Wolf Perez, ... Biochemistry 58 (24), 2750-2759, 2019 | 20 | 2019 |
The immunological effects of oral polio vaccine provided with BCG vaccine at birth: a randomised trial KJ Jensen, HS Karkov, N Lund, A Andersen, HB Eriksen, AG Barbosa, ... Vaccine 32 (45), 5949-5956, 2014 | 16 | 2014 |
High throughput screening for rapid and reliable prediction of monovalent antibody binding behavior in flowthrough mode JK Lorek, HS Karkov, F Matthiesen, M Dainiak Biotechnology and Bioengineering, 2023 | | 2023 |
Bispecific antibodies: Screening from traditional to mixed-mode chromatography modalities for a purification solution T Matos, HS Karkov, G Andersen, L Sejergaard, H Ahmadian, S Cramer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
Insights into the nature of multimodal chromatographic selectivity using in silico designed Fab fragment variants HS Karkov, H Ahmadian, BO Krogh, A Bogsnes, S Cramer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015 | | 2015 |
Investigations into multimodal chromatographic selectivity using in silico designed Fab fragment variants and column modeling HS Karkov Rensselaer Polytechnic Institute, 2015 | | 2015 |
Investigations on Fab fragment variants in multimodal chromatographic systems HS Karkov, S Parimal, J Woo, H Ahmadian, BO Krogh, A Bogsnes, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014 | | 2014 |
Modeling multimodal chromatographic behavior in column systems HS Karkov, L Sejergaard, H Ahmadian, A Bogsnes, SM Cramer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |
Investigation of protein selectivity in multimodal chromatography using an in silico designed Fab library HS Karkov, J Woo, S Parimal, H Ahmadian, A Bogsnes, BO Krogh, ... | | |