Modeling steatohepatitis in humans with pluripotent stem cell-derived organoids R Ouchi, S Togo, M Kimura, T Shinozawa, M Koido, H Koike, ... Cell metabolism 30 (2), 374-384. e6, 2019 | 380 | 2019 |
Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish HA McCauley, JM Wells Development 144 (6), 958-962, 2017 | 295 | 2017 |
Three cheers for the goblet cell: maintaining homeostasis in mucosal epithelia HA McCauley, G Guasch Trends in molecular medicine 21 (8), 492-503, 2015 | 215 | 2015 |
Human stomach-on-a-chip with luminal flow and peristaltic-like motility KK Lee, HA McCauley, TR Broda, MJ Kofron, JM Wells, CI Hong Lab on a Chip 18 (20), 3079-3085, 2018 | 97 | 2018 |
TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium HA McCauley, CY Liu, AC Attia, KA Wikenheiser-Brokamp, Y Zhang, ... Development 141 (23), 4628-4639, 2014 | 55 | 2014 |
A comprehensive structure-function study of neurogenin3 disease-causing alleles during human pancreas and intestinal organoid development X Zhang, PS McGrath, J Salomone, M Rahal, HA McCauley, J Schweitzer, ... Developmental cell 50 (3), 367-380. e7, 2019 | 42 | 2019 |
Deriving functional human enteroendocrine cells from pluripotent stem cells KL Sinagoga, HA McCauley, JO Múnera, NA Reynolds, JR Enriquez, ... Development 145 (19), dev165795, 2018 | 40 | 2018 |
Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport HA McCauley, AL Matthis, JR Enriquez, JT Nichol, JG Sanchez, WJ Stone, ... Nature communications 11 (1), 4791, 2020 | 35 | 2020 |
Tissue responses to Shiga toxin in human intestinal organoids S Pradhan, SS Karve, AA Weiss, J Hawkins, HM Poling, MA Helmrath, ... Cellular and molecular gastroenterology and hepatology 10 (1), 171-190, 2020 | 33 | 2020 |
Enteroendocrine regulation of nutrient absorption HA McCauley The Journal of Nutrition 150 (1), 10-21, 2020 | 33 | 2020 |
Ontogeny and function of the circadian clock in intestinal organoids AE Rosselot, M Park, M Kim, T Matsu‐Ura, G Wu, DE Flores, ... The EMBO Journal 41 (2), e106973, 2022 | 29 | 2022 |
A dietary change to a high-fat diet initiates a rapid adaptation of the intestine JR Enriquez, HA McCauley, KX Zhang, JG Sanchez, GT Kalin, RA Lang, ... Cell reports 41 (7), 2022 | 25 | 2022 |
De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones HA McCauley, V Chevrier, D Birnbaum, G Guasch Elife 6, e22914, 2017 | 17 | 2017 |
Using Human Induced Pluripotent Stem Cell–Derived Organoids to Identify New Pathologies in Patients With PDX1 Mutations M Krishnamurthy, DO Kechele, T Broda, X Zhang, JR Enriquez, ... Gastroenterology 163 (4), 1053-1063. e7, 2022 | 13 | 2022 |
Serial orthotopic transplantation of epithelial tumors in single-cell suspension HA McCauley, G Guasch Stem Cell Niche: Methods and Protocols, 231-245, 2013 | 10 | 2013 |
Enteroendocrine cells protect the stem cell niche by regulating crypt metabolism in response to nutrients HA McCauley, AM Riedman, JR Enriquez, X Zhang, ... Cellular and Molecular Gastroenterology and Hepatology 15 (6), 1293-1310, 2023 | 7 | 2023 |
Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon JO Múnera, DO Kechele, C Bouffi, N Qu, R Jing, P Maity, JR Enriquez, ... Cell Stem Cell 30 (11), 1434-1451. e9, 2023 | 5 | 2023 |
Transplanted human intestinal organoids: a resource for modeling human intestinal development A Singh, HM Poling, P Chaturvedi, K Thorner, N Sundaram, DO Kechele, ... Development 150 (9), dev201416, 2023 | 5 | 2023 |
Sweet relief: Reprogramming gastric endocrine cells to make insulin HA McCauley, JM Wells Cell Stem Cell 18 (3), 295-297, 2016 | 5 | 2016 |
Generation of human intestinal organoids containing tissue-resident immune cells K Tominaga, D Kechele, G Sanchez, H McCauley, J Enriquez, S Vales, ... Inflammatory Bowel Diseases 28 (Supplement_1), S57-S57, 2022 | 3 | 2022 |