The signaling mechanism of ROS in tumor progression WS Wu Cancer and Metastasis Reviews 25, 695-705, 2006 | 907 | 2006 |
Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species WS Wu, JR Wu, CT Hu Cancer and Metastasis Reviews 27, 303-314, 2008 | 193 | 2008 |
Reactive oxygen species mediated sustained activation of protein kinase C α and extracellular signal-regulated kinase for migration of human hepatoma cell Hepg2 WS Wu, RK Tsai, CH Chang, S Wang, JR Wu, YX Chang Molecular Cancer Research 4 (10), 747-758, 2006 | 123 | 2006 |
Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1 WS Wu, RI You, CC Cheng, MC Lee, TY Lin, CT Hu Scientific reports 7 (1), 17753, 2017 | 86 | 2017 |
Snail associates with EGR‐1 and SP‐1 to upregulate transcriptional activation of p15INK4b CT Hu, TY Chang, CC Cheng, CS Liu, JR Wu, MC Li, WS Wu The FEBS journal 277 (5), 1202-1218, 2010 | 57 | 2010 |
Reactive oxygen species-mediated PKC and integrin signaling promotes tumor progression of human hepatoma HepG2 CT Hu, JR Wu, CC Cheng, S Wang, HT Wang, MC Lee, LJ Wang, SM Pan, ... Clinical & experimental metastasis 28, 851-863, 2011 | 52 | 2011 |
The therapeutic targeting of HGF/c-met signaling in hepatocellular carcinoma: alternative approaches CT Hu, JR Wu, CC Cheng, WS Wu Cancers 9 (6), 58, 2017 | 50 | 2017 |
Involvement of p-15INK4b and p-16INK4a gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells WS Wu, HY Hsu Biochemical and Biophysical Research Communications 285 (2), 183-187, 2001 | 49 | 2001 |
The transcriptional factor Snail simultaneously triggers cell cycle arrest and migration of human hepatoma HepG2 CT Hu, JR Wu, TY Chang, CC Cheng, WS Wu Journal of biomedical science 15, 343-355, 2008 | 46 | 2008 |
PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression JP Mandal, CN Shiue, YC Chen, MC Lee, HH Yang, HH Chang, CT Hu, ... Free Radical Biology and Medicine 163, 69-87, 2021 | 44 | 2021 |
Dengue virus and antiplatelet autoantibodies synergistically induce haemorrhage through Nlrp3-inflammasome and FcүRIII TS Lien, DS Sun, CM Chang, CY Wu, MS Dai, H Chan, WS Wu, SH Su, ... Thrombosis and haemostasis 113 (05), 1060-1070, 2015 | 41 | 2015 |
Hydrogen peroxide inducible clone-5 mediates reactive oxygen species signaling for hepatocellular carcinoma progression JR Wu, CT Hu, RI You, SM Pan, CC Cheng, MC Lee, CC Wu, YJ Chang, ... Oncotarget 6 (32), 32526, 2015 | 37 | 2015 |
PKC mediates fluctuant ERK-paxillin signaling for hepatocyte growth factor-induced migration of hepatoma cell HepG2 CT Hu, CC Cheng, SM Pan, JR Wu, WS Wu Cellular Signalling 25 (6), 1457-1467, 2013 | 31 | 2013 |
High mobility group B1 up-regulates angiogenic and fibrogenic factors in human retinal pigment epithelial ARPE-19 cells YC Chang, CW Lin, MC Hsieh, HJ Wu, WS Wu, WC Wu, YH Kao Cellular Signalling 40, 248-257, 2017 | 30 | 2017 |
Enhanced PKCδ and ERK signaling mediate cell migration of retinal pigment epithelial cells synergistically induced by HGF and EGF YJ Chen, RK Tsai, WC Wu, MS He, YH Kao, WS Wu Public Library of Science 7 (9), e44937, 2012 | 30 | 2012 |
The role of endosomal signaling triggered by metastatic growth factors in tumor progression CT Hu, JR Wu, WS Wu Cellular signalling 25 (7), 1539-1545, 2013 | 29 | 2013 |
Oxidation of heat shock protein 60 and protein disulfide isomerase activates ERK and migration of human hepatocellular carcinoma HepG2 CY Lin, CT Hu, CC Cheng, MC Lee, SM Pan, TY Lin, WS Wu Oncotarget 7 (10), 11067, 2016 | 27 | 2016 |
Preclinical trials for prevention of tumor progression of hepatocellular carcinoma by LZ-8 targeting c-Met dependent and independent pathways JR Wu, CT Hu, RI You, PL Ma, SM Pan, MC Lee, WS Wu PLoS One 10 (1), e0114495, 2015 | 24 | 2015 |
Dengue virus envelope protein domain III induces Nlrp3 inflammasome-dependent NETosis-mediated inflammation in mice TS Lien, DS Sun, SC Hung, WS Wu, HH Chang Frontiers in Immunology 12, 618577, 2021 | 22 | 2021 |
PKCε-mediated c-Met endosomal processing directs fluctuant c-Met-JNK-paxillin signaling for tumor progression of HepG2 CT Hu, CC Cheng, JR Wu, SM Pan, WS Wu Cellular Signalling 27 (7), 1544-1555, 2015 | 20 | 2015 |