Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape R Gordân, N Shen, I Dror, T Zhou, J Horton, R Rohs, ML Bulyk Cell reports 3 (4), 1093-1104, 2013 | 347 | 2013 |
Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo X Qi, MH Disatnik, N Shen, RA Sobel, D Mochly-Rosen Molecular biology of the cell 22 (2), 256-265, 2011 | 295 | 2011 |
Quantitative modeling of transcription factor binding specificities using DNA shape T Zhou, N Shen, L Yang, N Abe, J Horton, RS Mann, HJ Bussemaker, ... Proceedings of the National Academy of Sciences 112 (15), 4654-4659, 2015 | 255 | 2015 |
Proteome-wide mapping of short-lived proteins in human cells J Li, Z Cai, LP Vaites, N Shen, DC Mitchell, EL Huttlin, JA Paulo, BL Harry, ... Molecular cell 81 (22), 4722-4735. e5, 2021 | 75 | 2021 |
Establishment of expression in the SHORTROOT-SCARECROW transcriptional cascade through opposing activities of both activators and repressors EE Sparks, C Drapek, A Gaudinier, S Li, M Ansariola, N Shen, ... Developmental Cell 39 (5), 585-596, 2016 | 60 | 2016 |
Divergence in DNA specificity among paralogous transcription factors contributes to their differential in vivo binding N Shen, J Zhao, JL Schipper, Y Zhang, T Bepler, D Leehr, J Bradley, ... Cell systems 6 (4), 470-483. e8, 2018 | 50 | 2018 |
p38α regulates expression of DUX4 in a model of facioscapulohumeral muscular dystrophy LA Rojas, E Valentine, A Accorsi, J Maglio, N Shen, A Robertson, ... Journal of Pharmacology and Experimental Therapeutics 374 (3), 489-498, 2020 | 34 | 2020 |
Integration of cancer gene co-expression network and metabolic network to uncover potential cancer drug targets J Chen, M Ma, N Shen, JJ Xi, W Tian Journal of proteome research 12 (6), 2354-2364, 2013 | 27 | 2013 |
Single-cell gene fusion detection by scFusion Z Jin, W Huang, N Shen, J Li, X Wang, J Dong, PJ Park, R Xi Nature Communications 13 (1), 1084, 2022 | 13 | 2022 |
Low-input lipidomics reveals lipid metabolism remodelling during early mammalian embryo development L Zhang, J Zhao, SM Lam, L Chen, Y Gao, W Wang, Y Xu, T Tan, H Yu, ... Nature Cell Biology, 1-16, 2024 | 4 | 2024 |
P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD AM Cacace, LGAR SOTO, LA Thompson III, OB Wallace, LV Ronco, ... US Patent 10,537,560, 2020 | 4 | 2020 |
Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics L Lv, T Zhang, H Jia, Y Zhang, A Ahsan, X Zhao, T Chen, Z Shen, N Shen Frontiers in Immunology 13, 995998, 2022 | 3 | 2022 |
P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD AM Cacace, LGAR SOTO, LA Thompson III, OB Wallace, LV Ronco, ... US Patent 10,342,786, 2019 | 3 | 2019 |
Use of p38 inhibitors to reduce expression of DUX4 AM Cacace, SLGA Rojas, LA Thompson, OB Wallace, L Ronco, N Shen, ... | 2 | 2021 |
Intrinsic specificity differences between transcription factor paralogs partly explain their differential in vivo binding N Shen, J Zhao, J Schipper, Y Zhang, T Bepler, D Leehr, J Bradley, ... bioRxiv, 208561, 2017 | 2 | 2017 |
De novo identification of expressed cancer somatic mutations from single-cell RNA sequencing data T Zhang, H Jia, T Song, L Lv, DC Gulhan, H Wang, W Guo, R Xi, H Guo, ... Genome Medicine 15 (1), 115, 2023 | 1 | 2023 |
Beyond radiologist-level liver lesion detection on multi-phase contrast-enhanced CT images by deep learning L Wu, H Wang, Y Chen, X Zhang, T Zhang, N Shen, G Tao, Z Sun, Y Ding, ... Iscience 26 (11), 108183, 2023 | 1 | 2023 |
Use of p38 inhibitors to reduce expression of DUX4 AM Cacace, LGAR SOTO, LA Thompson III, OB Wallace, LV Ronco, ... US Patent 11,479,770, 2022 | 1 | 2022 |
Aberrant mitochondrial fission in neurons induced by delta protein kinase C under oxidative stress conditions, in vivo X Qi, MH Disatnik, N Shen, RA Sobel, D Mochly-Rosen Mol Biol Cell [Europe PMC free article][Abstract][Google Scholar], 0 | 1 | |
Identifying autism spectrum disorder from multi-modal data with privacy-preserving H Wang, H Jing, J Yang, C Liu, L Hu, G Tao, Z Zhao, N Shen npj Mental Health Research 3 (1), 15, 2024 | | 2024 |